ohsures1 said:
funny you should ask- (well it is not FUNNY) but you get my point- yes - I take 150 mg of effexor daily....think this may be a source for my 'stuck' metabolism?
I believe this definitely has something to do with things. I have worked with various people during my days as a personal trainer and strength and conditioning coach. I have never had a client not make their goal or deadline in regards to weight loss or performance. I had about 5 cases where no matter what changes we made to their diet and training program, the person would not lose weight and sometimes to my amazement, actually gained weight.
Finally, after reflecting on our sessions, I decided to review their medical history questionares. 3 of them had listed using SSRI's and the other 2 said that they were not on any medication. I always felt one of them was somewhat mentally unstable so I pulled her aside on day and bluffed her by saying "Why did you lie to me on your Medical History Questionare?" She folded and came clean. The other one openly admitted to it when I asked her and originally thought that it was really not a big deal to mention something like that.
Moving on, I was baffled by this phenomenon and started compliling as much data as I could on the condition. I learned quite a bit from those studies and was able to form a hypothesis about SSRI's and the associated weight gain or difficulties in weight loss. Obviously, Effexor is not an SSRI. The weight related problems are not as severe but may still be related in some way.
A reocurring piece of data in those studies was the neuroendocrine system and a fat cell derrived hormone called Leptin. Leptin reduces the uptake of food and increases energy expenditure. The alteration of Leptin has been shown to directly cause weight gain for certain people using an SSRI.
Adipocyte plays a major role in Leptin regulation. Unfortunately, this is not something you can supplement. Therefore I took deeper look in to the origins and metabolism of Adipocyte and found that Essential Fatty Acids directly regulate Adipocyte and Leptin. Essential Fatty Acids are the precursors (comes before, or needed to make) for both Adipocyte and Leptin.
We started using an OMEGA 3 (EPA/DHA) supplement at 2,400 mgs daily. Slowly, we worked out way up to 7,200 mgs daily over the course of two to three weeks. The results were quite impressive. Four out of the five clients experienced an average weight loss of about 15 lbs and only one of the clients did not lose weight. I should also note that the supplementation of the EFA's stopped her from gaining anymore weight. Unfortunately, she became discouraged and quit.
Jenetic