I shoot it sub-q on the side of my belly.
The fact that it is cold is not what makes it burn and I always shoot it right out of the fridge. I have a script for it (HRT) and I use and have always used Novarel. Some places are just more sensitive than others. I get a burner every now and then. In fact, HCG - human chorionic gonadotropin - goes bad if left at room temperature for too long. I'm not sure how long exactly, but I left a bottle out about a year ago. It was out for about 2 hours. I called the pharmacy and they told me to toss it. I was also using HCG only as HRT awhile back and went camping with it. My ice chest tipped over and all of the ice and water spilled out. The HCG didn't feel cold by the time I found it. We were gone that entire week and I felt like SHIT. It's great stuff, but the keeping it cold thing is a hassle.
R1