Guggulsterones. Good-Bad-Other?

[TADHealth]

Guggulsterones E&Z inside a supplement.

What are thr pos and cons? Seems most are avoiding them these days. But not everyone. I am losing weight/fat and was considering using a supplement that included them for a coupel weeks.

K for quality feedback and insight.

 

[macrophage69alpha]

guggulsterones are promiscuous steroid receptor ligands. they are antagonistic of the androgen receptor, strongly agonistic of the progesterone receptor and weakly agonistic of the estrogen receptor.

there is no evidence they have any impact on thyroid as claimed and their impact on cholesterol has been discredited, with recent studies showing a mild increase in cholesterol.

IMHO they are too be avoided for fat loss and bodybuilding purposes.

 

[PIGEON-RAT]

What about for acne purposes? I remember reading a while back that at moderately high doses they cleared the skin up nicely. Do the costs outweigh the benefits?

 

[macrophage69alpha]

there are plenty of other supps for acne, the most common other side effect of guggulsterones is dermatitis (allergen)