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To read the ads selling gamma-hydroxybutarate (GHB) as a growth hormone releaser and anabolic agent, you would think it had received rave reviews from the scientific community. Not so. GHB was researched by pharmaceutical companies in the '70s as a possible sleep aid, and canned when it proved to be unpredictable and dangerous.
GHB was first identified in France in 1960 as a naturally occurring substance in the human brain. Later it was shown to be an intermediate metabolite in the production of sleep. Oral GHB supplements do produce sleep. The 5-gram doses being touted for muscle building will knock most people out cold.
There is also some evidence that GHB causes the pituitary to release growth hormone in healthy men. This study, however, used intravenous injections of GHB. There are no studies of oral use of GHB to release growth hormone. But the strong effects of oral GHB on brain function, show that it does get to the brain via the oral route, and would probably work.
It is those strong effects that also cause the trouble. From June to November 1990, the Center for Disease Control recorded 57 cases of GHB poisoning. One of the worst problems is its unpredictability. People using GHB successfully for insomnia, may suddenly start getting headaches, vertigo and tremors during the day and disturbances of the heart. The worst cases show full blown epileptic seizures and comas.
The Food and Drug Administration issued a public warning against GHB in November of 1990, and it has since been banned.
GHB was first identified in France in 1960 as a naturally occurring substance in the human brain. Later it was shown to be an intermediate metabolite in the production of sleep. Oral GHB supplements do produce sleep. The 5-gram doses being touted for muscle building will knock most people out cold.
There is also some evidence that GHB causes the pituitary to release growth hormone in healthy men. This study, however, used intravenous injections of GHB. There are no studies of oral use of GHB to release growth hormone. But the strong effects of oral GHB on brain function, show that it does get to the brain via the oral route, and would probably work.
It is those strong effects that also cause the trouble. From June to November 1990, the Center for Disease Control recorded 57 cases of GHB poisoning. One of the worst problems is its unpredictability. People using GHB successfully for insomnia, may suddenly start getting headaches, vertigo and tremors during the day and disturbances of the heart. The worst cases show full blown epileptic seizures and comas.
The Food and Drug Administration issued a public warning against GHB in November of 1990, and it has since been banned.
