GHB Alternative - Tranquili-G?!

[rogerwilcox]

I'm excited about the potential here, but want to know if any of the bros and sisters here have tried it.

It's seems like the main complaint I hear against it is that it doesn't get you "high" like GHB.

My only interest in GHB and it's analogues is for health.

If Tranquili-G increases GH levels and helps you sleep, I can live without the high (hey, if you wanna get high, go smoke some herb, I say).

Does anyone have any experience with Tranquili-G in this way? Does it truly increase GH levels to the same extent as GHB? As for the sleep, I hear it helps you relax, but doesn't knock you out the way G does - but lasts longer so helps you sleep for longer periods of time and not the short 3 hours of G sleep.

Does it also help you store up dopamine in the brain so you're wide awake when you wake up after taking the stuff?

Anyway, please don't respond with "well, I heard so and so say". Please post your personal experiences with or scientific discussions of the uses of tranquili-G. Or links to more info.

The marketing for it looks good, of course, but so does the marketing for a lot of snake oil.

Let's get some facts. If it is what I think, I'm stoked.

Peace,

Roger Jr.

 

[Ryvor]

I've read it's not that good.
Try it and let us know.

 

[-{ GODZILLABOL }-]

Bump!

 

[diamonddiceclay]

according to duchaine, "ghb can probably raise gh in individuals who can still secrete GH w/ stimulus,however, this ability declines radically with age"-he also said that ghb raises CORTISOL

 

[rogerwilcox]

bump for more responses - this could be important - in that it will help people find a potential great new supplement or prevent them from getting ripped off by taking junk - anyone tried it?

 

[Jacob Creutzfeldt]

Ask Par Deus

I think Par Deus, who posts on the supplement board, runs Avant Labs (the distributor of Tranquil-G). I'm sure he would have more info.

 

[rogerwilcox]

Jacob - thanks, bro.

I sent a private message to par deus. Hope he checks that. Anyone else here know how to get in touch with him, please pass the word on that his response is requested here. I'm sure he'll have some good stuff to say.

 

[rogerwilcox]

Barring any response from Par Deus yet (I'm sure he's just busy), I found the following posted on his site:

http://www.avantlabs.com/cgi-sz/webcwrap/szw/ai_rebuttal.htm?sid=4yWNn20HE4uY3HL-23101024839.98

Looks like Anabolic Insider wrote a negative article about Tranquili-G and Par Deus is defending himself (quite eloqently, I should add) here.

Can anyone get Par Deus in here to give us some info? Do they have any scientfic info about the effectiveness of this new drug on sleep, GH levels, and dopamine?

Anyone have any facts or any experiences to share?

Roger Jr.

 

[Par Deus]

There is not a great deal of direct data on the direct effects of 4-pentanolide, the active ingredient in Tranquili-G, so we can only speculate -- however, there is good data for speculation, so it is not just a W.A.G.

The physiological effects produced by GHB that we cannot directly feel (i.e. reductions in anxiety should be obvious) such as increases in growth hormone are well established with oral usage of moderate dosing. Growth Hormone increases of 300% are seen with an oral dose of 1.5g.

GHB works, initially via binding with specific GHB receptors (its actions are then modulated by various neurotransmitter systems (GABA, dopamine, opioid, etc.). The conversion product of 4-pentanolide, GHV, has been found to bind to the GHB receptor (with greater affinity than GHB), so it would be expected to produce the same type of physiological effects.

On paper, they would be expected to be stronger, but this has not been the case, likely due to a transport issue, or weak post-receptor signalling.

So, the question is -- how does the signal actually produced compare to 1.5g of GHB -- which was adequate to produce a 300% increase in growth hormone. For this, we can compare the subjective psychoactive effects, since, as mentioned, it works through specific receptors, thus different binding to another receptor system can be ruled out, as can modulation by a metabolite, because there are none with significant activity.

Comparing the subjective effects -- the dose of 4-pentanolide in Tranquili-G feels like about 1-1.5g of GHB -- but, it lasts longer.

So, the best guess, given what we know, is that it would have a similar effect on GH, pehaps slightly less, but that it would last longer.

Its effects on REM sleep, dopamine, and everything else, would also be quite similar in type, with a lower magnitude, but of a longer duration.

 

[rogerwilcox]

Thanks for the helpful reply, Par.

Couple quick questions:

a. If one increases the dose, can you match the other effects of GHB? (inebriation, etc.) Frankly, if it doesn't totally knock you out (and just makes you really sleepy), that's a plus for me as it will stay legal longer.

b. Does it make you tired enough to really help sleep? If Melatonin was a 1 (little tired) and GHB was a 10 (knocking you on your ass), where would tranquili-g be on that scale?

c. Do you plan to conduct any tests measuring the GH, dopamine, and sleep effects of tranquili-g?

As you know, your substance has huge potential. If you could prove it's efficacy you'll be a very rich man. Most of the people on the board here will be very interested - the implications for bodybuilding are huge.

Peace,

Roger

 

[Par Deus]

Thanks for the helpful reply, Par.

Couple quick questions:

a. If one increases the dose, can you match the other effects of GHB? (inebriation, etc.) Frankly, if it doesn't totally knock you out (and just makes you really sleepy), that's a plus for me as it will stay legal longer.

b. Does it make you tired enough to really help sleep? If Melatonin was a 1 (little tired) and GHB was a 10 (knocking you on your ass), where would tranquili-g be on that scale?

c. Do you plan to conduct any tests measuring the GH, dopamine, and sleep effects of tranquili-g?

As you know, your substance has huge potential. If you could prove it's efficacy you'll be a very rich man. Most of the people on the board here will be very interested - the implications for bodybuilding are huge.

Peace,

Roger

One cannot increase the effects by increasing the dosages -- this is due to the transport/signalling issue that I mentioned.

It definitely makes most people tired enough to really help sleep (the exception is the person who typically takes 10+ g of GHB throughout the day or someone who is super-wired from meth or a dose of EC ten minutes earlier) -- on your 1-10 scale, I would say probably 5-6.

We will likely do testing at some point, but such things are expensive, so I cannot give a definite answer as to when.

 

[Par Deus]

BTW, I am considering your GHB that scores a "10", a 2-3+ gram, truly knock-you-out dose.

 

[rogerwilcox]

Cool. Thank, Par. I'm going to order some and give it a shot. I'll post my experiences here. Hell, if it can make me sleep (without the next day groginess from Melatonin and Benadryl), then it will get my vote!

Roger Jr.

 

[yokedaddy]

bros, do not waste your time or money w/ this BS product. the only thing it does is taste like shit. i initially used it at the recommended dose of 1 teaspoon. possibly, it made me a bit tired. no other effects could be determined. i then gradually increased my dosage (by teaspoon) to a max of 4 teaspoons. again, i felt no additional benefits from it. i'm well versed in ghb, gbl, and 1.4bd, IMO this product is a complete waste.

sorry to burst any bubbles.

 

[rogerwilcox]

Hey Yoke, thanks for the feedback.

Is it fairly easy to get gbl or 1.4? I hear a lot of people saying that packages of even those chemicals are getting raided and that gbl will "test positive" for gbh.

I'm very interetsted in the substance as a sleep aid that doesn't jack up your brain chemistry in negative ways. However, I have heard that some people do, indeed, become addicted to gbh. On the other hand, it seems that most of those people were big time users (gobs of it every day).

If someone were to take only a small amount each night for sleep is this phsyical addiction likely? (Of course *everything* has the potential for psychological addiction, so I'm not too worried about that.) I just see all of the G support groups all over the place, so I assume there must be some validity to the addiction issue.

Thanks in advance for your help - it's good to have someone with some experience with these chemicals on the board.

Roger Jr.

 

[Par Deus]

bros, do not waste your time or money w/ this BS product. the only thing it does is taste like shit. i initially used it at the recommended dose of 1 teaspoon. possibly, it made me a bit tired. no other effects could be determined. i then gradually increased my dosage (by teaspoon) to a max of 4 teaspoons. again, i felt no additional benefits from it. i'm well versed in ghb, gbl, and 1.4bd, IMO this product is a complete waste.

sorry to burst any bubbles.

Did you not believe our website when we specifically stated that it does not fuck you up like GHB/GBL and that there is a ceiling on the effects, thus increasing the dosage will not help??

 

[rogerwilcox]

He may have missed that, dude - let's give him the benefit of the doubt. I assume he is looking for the "high" one gets from GHB, and I can't blame him. Personally, I just want the sleep benefits... Wish I could score some real G, though. Anyway, I ordered the Tranquili-g and will post my experience here. If it puts me to sleep and I feel good when I wake up you'll have my thumbs up.

Still want to try some real G, though, since it's so well studied.

 

[rogerwilcox]

Got my tranquili-g today. I'll try it tonight and let you all know how it goes...

 

[drrman]

i agree with yokedaddy, if you want the effects of G, then get you some G. Yes it's illegal, but the chemicals to make it aren't illegal to possess. The gamma butrylactone is a watched chemical, but isn't scheduled such as GHB to possess(commonly sold as nail polish remover and cleaner by certain stores), I suggest anyone who badly wants to take G for bodybuilding reasons to search like hell on the net and G isn't hard to make considering you have a few common items. Plus, the recipes are straight forward and if you use gram scales and follow the recipe, you will know your exact concentration of G and can therefore use it as you wish. This is the only way one should take G, either make it or completely trust someone who is making it for you.

 

[rogerwilcox]

Update - I tried it. Can't say it affected me too much... After taking the dose, I waited an hour. Can't say I felt any different. I then drank a glass of wine. Felt a little bit tired, tried to sleep, but ended up staying awake longer than normal...

Repeated the next night to almost the same effect. Even tried a 2nd dose - no difference.

I'm going to forget the whole GHB thing. Too many reports of addiction.

Last night I took some diphenhydramine, valerian root and melatonin. Knocked my ass out and I slept like a baby! I was just tired today, though...

Wish there was some way to get a good night's sleep and feel great the next day... Any suggestions?

 

[yokedaddy]

tranquil-g is a waste, i'll go so far as to say false advertisement - 'mood enhancer' WTF???. i'm experimenting w/ deprenyl, piracetam, and vasopressin currently. an update will follow...

 

[gainerxxl]

I really don´t understand how anyone can sleep of GHB/GBL and wake up refreshed. Everytime I take it it gives me energy, just like an E would do. When I take too much it knocks me out for like 3 hours and I wake up feeling like shit.
All of my friend experienced the same thing, some can´t sleep all night long after taking G. I sometimes even pop a Valium to go to sleep after a good GBL binge, but I still feel like crap the next day.
I don´t buy that GH releasing thing either, it´s just to good to be true. In Addition G gives me terrible munchies, I eat until I´m sick. It´s great to give you a buzz but I would´not even consider to take it for health benefits.

 

[Fonz]

Bought thtree bottles of the stuff.

Been giving it a whirl for 3 days now.

Comments:

1. Not like GHB at all. Don't expect to get the floating,
dopamine love-rush feeling. Feels more like the "calm" you feel
after a workout and your sitting on a very comfy sofa.

2. Tastes horribly bad. And I do mean bad. Sorry Par Deus,
but damn......I thought I could suck it in....but nope.

Food+Tranquil-G = Trip to the WC

It took me a while, but the best thing to mix the Tranquil- with is
Peach Snapple Ice Tea. Masks the taste reasonably well.

Also, tested out the more is better theory. Nope. After 10ml
nothing......it levels off.

I give it a 7/10

Compared to GHB? A 5/10

Fonz

 

[Lumberg]

I have a bottle I bough months ago..tried it three times, once with my gf...nothing. Never done The real thing but I do use antihistamines sometimes and this doesn't even compare to those. The last time the taste wa sso awful and it burned my throat so much it actualy kept me up longer.

Shoulda gotten my money back but was too lazy. If anyone wants to buy 3/4 of a bottle of this stuff PM me.

JC

 

[Dante B.]

The subjective response from this varies greatly and it's impossible to judge ahead of time as to whether or not one will be met with satisfaction or wanting---hence the offer of refund (for direct purchases).

The taste to the tongue of many is horrible, masked only by juice of some sorts. I can take it straight with water, but that's certain not to be the joy of most.