Fina's affect on DNA

[Shaved Ape]

IPSON, you need to chill out and really evaluate who is REALLY full of shit and who doesn't know shit. There is nothing wrong with using the board to seek out knowledge and information, regardless of how vague or incoherent one's question may be. And there is no need to judge someone like you, who obviously doesn't know what they are talking about anyways. But here you have asked a question which clearly highlights your own ignorance on a subject, and then attacked Dr. X when he tries to give you an accurate response.

Dr. X and Huck both make very valid points here. IPSON, you need to learn how to shut up and listen, without getting defensive when someone offers you information that you cannot understand.

 

[IPSON]

While the genome may not be altered,there is evidence to suggest that certain steroids have the ability to increase myonucleonic populations over the long haul(testosterone in particular).That would certainly qualify as a shift in more favorable genetic potential(ability to utilize proteins).Just a thought.

Thank you!

 

[Shaved Ape]

IPSON, you need to chill out and really evaluate who is REALLY full of shit and who doesn't know shit. There is nothing wrong with using the board to seek out knowledge and information, regardless of how vague or incoherent one's question may be. And there is no need to judge someone like you, who obviously doesn't know what they are talking about anyways. But here you have asked a question which clearly highlights your own ignorance on a subject, and then attacked Dr. X when he tries to give you an accurate response.

Dr. X and Huck both make very valid points here. IPSON, you need to learn how to shut up and listen, without getting defensive when someone offers you information that you cannot understand.

 

[IPSON]

IPSON, you need to chill out and really evaluate who is REALLY full of shit and who doesn't know shit. There is nothing wrong with using the board to seek out knowledge and information, regardless of how vague or incoherent one's question may be. And there is no need to judge someone like you, who obviously doesn't know what they are talking about anyways. But here you have asked a question which clearly highlights your own ignorance on a subject, and then attacked Dr. X when he tries to give you an accurate response.

Dr. X and Huck both make very valid points here. IPSON, you need to learn how to shut up and listen, without getting defensive when someone offers you information that you cannot understand.

Look fuckface, do you see the smile after the posts....use your fucking imagination....Now I'm calling you a dumbfuck without the smile. Chill bro, I was just fucking with him. If I knew the answer to the question then i would never had asked.

 

[Shaved Ape]

I'm the dumbfuck eh? So why don't you tell me all about the effects of AS on YOUR DNA, because apparently you were right. It seems that Fina has affected your genetically-programmed survival skills, causing you to call people that you do not know and who are much more informed on topics such as molecular biology than you dumbfucks.

 

[flo0rida fah q]

tisk tisk tisk

lets fight some more over the internet

cause you know, it really does a lot of good :laugh:

 

[Shaved Ape]

you're right florida, it is a waste of everyone's time. But members should be able to post intelligent responses without being insulted by those asking the questions, or anyone else for that matter. Just wanted to get that straight. I'm chill, IPSON.

 

[IPSON]

I'm the dumbfuck eh? So why don't you tell me all about the effects of AS on YOUR DNA, because apparently you were right. It seems that Fina has affected your genetically-programmed survival skills, causing you to call people that you do not know and who are much more informed on topics such as molecular biology than you dumbfucks.

well then answer the question smart ass!

 

[Shaved Ape]

Fine IPSON, I will expand on the answers given by Dr.X and Huck. First, the question as STATED involved the effects of FINA/AR on DNA. Dr. X accurately answered that androgens do not alter your DNA, which functions as your genetic blueprint. All nucleated cells in your body contain a copy of your entire genome, in the form of billions of base pairs of DNA sequence. This blueprint encodes all the genes, which encode all the proteins, expressed in the body.

In any particular cell, only a subset of these genes will actually be expressed, or activated such that they are transcribed into RNA and then translated into protein. Androgens are likely to have an effect on the expression levels of particular proteins (such as myosin, etc) encoded by these genes. This is in part due to AS binding to the androgen receptors at the cell surface. These androgen-receptor complexes can then translocate to the cell nucleus and both directly and indirectly impact the transcription of certain genes. The DNA itself remains unaltered, as significant alterations in your genetic blueprint are likely to result in either cell death or transformation.

Huck also pointed out that AS may have an impact on the number and/or localization of muscle cell nuclei. Muscle cells are somewhat unique in that they are multinucleated (contain many nuclei distributed across the myofibers) and androgens may have an impact on the generation and/or distribution of myonuclei. An ongoing debate also exists as to whether AS and/or growth hormone primarily increase muscle mass through the hypertrophy of existing muscle fibers and/or through muscle cell hyperplasia, the generation of new muscle cells. But that is another long story.

 

[IPSON]

Are you really Ip's son?

sad but true