Femara and Arimidex together?

[drrman]

Ok im on sust and fina right now, just threw in the sust two weeks ago, i'm very susceptible to estrogen sides so i was taking one arimidex ED, im trying to stay very lean and hold NO water. I just received some femara, i have 20 femaras, and 30 arimidex right now. What does anyone think of taking an arimidex one day and a femara the next? or should i run the arimidex till i run out then start the femara? just curious here, the arimidex is working wonderfully so far.

 

[LONE_AZ]

No need to mess with something when it is not broken. Mixing the two will make no difference if the Arimidex is working fine. Leave thing the way they are.

 

[Lumberg]

I second that opinion. Taking both would be overkill, as they both do the exact same thing. It would be like taking aspirin AND ibuprofen for a headache that responds fine to just one.

JC

 

[Verbal Gorilla]

Just don't take femara with novoldex...

 

[TxLonghorn]

Just don't take femara with novoldex...

Why?

 

[Lumberg]

bump for the answer to this one (I have an idea but don't know enough about Nolvaldex)

JC

 

[perfectspecimen]

the answer is bc nolvadex lowers igf-1 54% and femara raises it around 25%.

 

[nandi12]

While letrozole is a potent antiaromatase, I would consider the claims of elevated IGF-1 resulting from its use as unproven at this time. A 1997 study showed an increase in IGF-1 levels in breast cancer patients treated with letrozole, but a more recent study in hypogonadal males shows no increase (1).

If I were the manufacturer (Novartis I believe) I would be worried if there were an increase in IGF-1 levels. IGF-1 is a potent mitogen implicated in the development and progression of breast cancer, the disease letrozole is designed to combat

(1) Eur J Endocrinol 2002 Mar;146(3):339-46

The role of sex steroids in the regulation of insulin sensitivity and serum lipid concentrations during male puberty: a prospective study with a P450-aromatase inhibitor.

Wickman S, Saukkonen T, Dunkel L.

Hospital for Children and Adolescents, University of Helsinki, PL281, FIN-00029 HUS, Helsinki, Finland.

 

[Verbal Gorilla]

Nobody knows why femara and novaldex and bad together, but both taking together is a much worse anti-e than femara taken alone, at the same does...

And nandi hit the nail on the head...

 

[el cubano]

Why?

You can take them together, but it has NOT been proven to be more effective IN BREAST CANCER PATIENCE.



PS. The study done on nolvadex lowering IGF-1 did NOT state any percentages and it was done on lactating women. That study holds no water with body builder use.