Wellbutrin has same SE's of most effective fat burners. Jitters, insomnia, increased alertness, hypermania, possible increased nervousness, perspiration, and so on. I would not suggest taking these together, medically, but I don't think that is what you are asking. Medical advise? You want bodybuilding advise. That would be, start a trial of the fat burner, like only one in the am, then increase as tolerated. Also, you will want to stay well hydrated to prevent dry-mouth.
I like Wellbutrin for depression if user does not have manic tendencies. I like it for smoking cessation as well. Half of any antidepressant's users will say it sucks. Its just that depressive symptoms are not easily treated with pills alone, and that antidepressive's effects are very individualized.