I wouldnt screw with the T4....Just my opinion...You will lose plenty of fat on the T3 alone....You must taper the T3...very important.....And double check the dosage of each tabs.....Comes in 25 & 50 mcg....I would not exceed 100mcg/day on any T3 cycle....Some more experienced vets can help you with the dosages per day.....And you can take the T3 once a day....The half-life allows you to do this without any problems...Fumunda