Drinking on a cycle

[Dr.M]

I think it depends what you call drinking too, some young people get fucking plastered.

I don't and wont drink on cycle at all however.

 

[Golden_Muscle]

I don't even drink off of a cycle. Both together is really stupid. It might not kill you, but it's better not to, But I think you already knew that.

 

[drveejay11]

From Fonz:

"Why alcohol is anathema to bodybuilding..... (post #1)

1: Alcohol Clin Exp Res 1997 Aug;21(5):792-8 Related Articles, Books, LinkOut


Studies on the time-course of ethanol's acute effects on skeletal muscle protein synthesis: comparison with acute changes in proteolytic activity.

Reilly ME, Mantle D, Richardson PJ, Salisbury J, Jones J, Peters TJ, Preedy VR.

Department of Clinical Biochemistry, King's College School of Medicine and Dentistry, London, United Kingdom.

A study of the effects of ethanol on skeletal muscle protein synthesis and protease activities was carried out in young male Wistar rats (150 g) for up to 24 hr after a single intraperitoneal dose of 75 mmol of ethanol/kg of body weight. At 20 min, the mean blood ethanol levels were 448 mg/dl. This level dropped steadily to zero through the following 24 hr.

So, this study basically looks at the effects of ethanol 24 hours
after drinking it.

Compared with pair-fed controls, significant reductions in total protein, RNA, and DNA contents were seen only after 24 hr in all skeletal muscles studied: changes were more marked in the muscles containing large proportions of type II fibers. In plantaris muscle, the fractional rate of protein synthesis (ks, %/day) did not fall 20 min after dosage but was reduced after 1 hr by 23% (p < 0.001), and by 63% after 24 hr, compared with control saline-injected rats (p < 0.001).

So, let us see.......23% reduction in protein synthesis after
1 hr and 63%!!!! after 24 hours.


This effect was independent of dietary intake because,

VERY IMPORTANT: Effect was independent of dietary intake.
SO, even with a PERFECT diet, ethanol still wreaks HAVOC
with your bodies anabolicity.

compared with the pair-fed group, the 24-hr ethanol-treated rats still showed a 52% decrease in fractional rates of protein synthesis (p < 0.001). Smaller reductions in ks were seen in soleus muscles in response to ethanol at 24 hr (-39%, p < 0.001). The activities of a variety of lysosomal and nonlysosomal proteases in plantaris muscle of 24-hr treated rats were not significantly affected by ethanol. Only alanyl- and tripeptidyl-aminopeptidase activities were reduced significantly (26%, p < 0.05 and 39%, p < 0.01, respectively). These results suggest that the muscle compositional changes seen over acute periods of ethanol toxicity are predominantly associated with impaired synthesis of protein and that the contribution of cellular proteolytic systems may be minimal.

Again,

The effects of ethanol on skeletal muscle protein metabolism are greater in muscles containing a predominance of type II fibers than in those containing mainly type I fibers.

Type II fibers= LARGE muscle fibers for TRAINING.
Type I=Fast twitch for activities like walking.

Ethanol's effects on muscle may be influenced by hormonal changes after 24 hr, because protein synthesis is still compromised and free plasma T3 and corticosterone are altered at this time-point.

Even worse, ethanol causes a HORMONAL shift. It increases
estrogen through the up-regulation of the aromatase enzyme,
lowers testosterone,increases cortisol and to boot reduces
free T3 levels.

PMID: 9267527 [PubMed - indexed for MEDLINE]

So, the next time you go drinking go for some non-alcoholic
drinks if on cycle. Or use an alcohol replacer.

If you drink, and wonder why you don't grow, well......
read and learn then, because this is for you. "

Fonz

 

[serge]

why do people still drink while they run gear??? if you can give up alcohol GIVE UP JUICING

 

[Golden_Muscle]

why do people still drink while they run gear??? if you can give up alcohol GIVE UP JUICING

Exactly, their either stupid, or just to wacked to understand anything. These are the type of guys that don't aspirate because they have lots of experience.

 

[solidspine]

Why in the world would you drink at all when on a cycle?


How old are you

 

[drveejay11]

Just being a dick and making sure people read this!

From Fonz:

"Why alcohol is anathema to bodybuilding..... (post #1)

1: Alcohol Clin Exp Res 1997 Aug;21(5):792-8 Related Articles, Books, LinkOut


Studies on the time-course of ethanol's acute effects on skeletal muscle protein synthesis: comparison with acute changes in proteolytic activity.

Reilly ME, Mantle D, Richardson PJ, Salisbury J, Jones J, Peters TJ, Preedy VR.

Department of Clinical Biochemistry, King's College School of Medicine and Dentistry, London, United Kingdom.

A study of the effects of ethanol on skeletal muscle protein synthesis and protease activities was carried out in young male Wistar rats (150 g) for up to 24 hr after a single intraperitoneal dose of 75 mmol of ethanol/kg of body weight. At 20 min, the mean blood ethanol levels were 448 mg/dl. This level dropped steadily to zero through the following 24 hr.

So, this study basically looks at the effects of ethanol 24 hours
after drinking it.

Compared with pair-fed controls, significant reductions in total protein, RNA, and DNA contents were seen only after 24 hr in all skeletal muscles studied: changes were more marked in the muscles containing large proportions of type II fibers. In plantaris muscle, the fractional rate of protein synthesis (ks, %/day) did not fall 20 min after dosage but was reduced after 1 hr by 23% (p < 0.001), and by 63% after 24 hr, compared with control saline-injected rats (p < 0.001).

So, let us see.......23% reduction in protein synthesis after
1 hr and 63%!!!! after 24 hours.


This effect was independent of dietary intake because,

VERY IMPORTANT: Effect was independent of dietary intake.
SO, even with a PERFECT diet, ethanol still wreaks HAVOC
with your bodies anabolicity.

compared with the pair-fed group, the 24-hr ethanol-treated rats still showed a 52% decrease in fractional rates of protein synthesis (p < 0.001). Smaller reductions in ks were seen in soleus muscles in response to ethanol at 24 hr (-39%, p < 0.001). The activities of a variety of lysosomal and nonlysosomal proteases in plantaris muscle of 24-hr treated rats were not significantly affected by ethanol. Only alanyl- and tripeptidyl-aminopeptidase activities were reduced significantly (26%, p < 0.05 and 39%, p < 0.01, respectively). These results suggest that the muscle compositional changes seen over acute periods of ethanol toxicity are predominantly associated with impaired synthesis of protein and that the contribution of cellular proteolytic systems may be minimal.

Again,

The effects of ethanol on skeletal muscle protein metabolism are greater in muscles containing a predominance of type II fibers than in those containing mainly type I fibers.

Type II fibers= LARGE muscle fibers for TRAINING.
Type I=Fast twitch for activities like walking.

Ethanol's effects on muscle may be influenced by hormonal changes after 24 hr, because protein synthesis is still compromised and free plasma T3 and corticosterone are altered at this time-point.

Even worse, ethanol causes a HORMONAL shift. It increases
estrogen through the up-regulation of the aromatase enzyme,
lowers testosterone,increases cortisol and to boot reduces
free T3 levels.

PMID: 9267527 [PubMed - indexed for MEDLINE]

So, the next time you go drinking go for some non-alcoholic
drinks if on cycle. Or use an alcohol replacer.

If you drink, and wonder why you don't grow, well......
read and learn then, because this is for you. "

Fonz

 

[Japanese machine]

I personally drink very little and I truely believe in fonz's thread. Its just that I am the only one of my friends that gears and they don't understand why I won't have a beer with them. I will have 1 or 2 at the most maybe 2 X month. I have never drank more then 12 beers in a month of a cycle. Its not that I don't have will power, its more of a social thing. I really don't think 2 beer 2X/month will be detramental to my gains or that toxic to my liver. I will give up dbol instead.

Twice a year MAX, but i do get shit faced; Birthday and Newyears. last year i didnt drink both though. If i do allow myself to drink it will only be on these days. If im out with a girl....priorities suddenly start to change......................

 

[jacobswell]

i think im the only one here who gets fucked no matter what he's on. even my last dbol and var cycle i was drinking. but hey, id rather have a good time then worry about gains. i did use a lot of milk thistle tho so maybe that helped.
i bet if u lot were not juicers many of u would drink.

 

[Slider]

I agree with Fonz's article and more should listen, Johnboy I do have a small amount of beers a month too just to avoid all the attention of friends thinking I’m juicing.

Slider