i've never had any negative issues with running liver protectants with my cycles. N2guard as judo said has a lot of vitamins, minerals in it. and its a must on a cycle to help control bp issues and protect your liver. so it would definately be a plus, not a negative. I've also read the same thing OP, and I can tell you that in my experience its not an issue at all.
the thing that may effect your orals is grapefruit or lemon juice being in your stomach and then taking the oral, but that is also debateable.
the thing that may effect your orals is grapefruit or lemon juice being in your stomach and then taking the oral, but that is also debateable.