If by detoxing you mean "cleaning up" your internal organs like liver and kidneys from different toxins, it's definitely good idea. You can do it while on gear (it won't flush it out of you in any way, lol!), while in PCT, or after that with different herbal supplements, vitamins, minerals and nutrients etc.
IME Aegis or TUDCA are great for detoxifying liver after using methylated orals, and getting everything back to normal liver vise.
N2Guard is all around great product for all vital organs, it has daily RDA of vitamins, but I personally go way above those recommendations with my daily nutrient intake, so I would add some good product that contains multiple vitamins, minerals, and nutrients in balance/correct ratio to each other. Those are what I personally use, especially after a blast when returning to my normal TRT dose. Depending on how heavy blast it's been, I will also add some-all of these: Lipid Stapil, Bp Stabil, and Liver Stabil.
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