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Deca / Sustanon 250 / Tren

Deca and tren can gyno issues by directly affecting the progesterone receptor. There is pretty much nothing you can do except lower progesterone expression by lowering estrogen, but with 2 powerful progestins, even doing that may not help much. Everyone I know that ran them together got painful nipples after 2 weeks and had to discontinue. I'm sure some have gotten away with it, but I doubt many.
 
I have run deca and then tren immediately after and have had serious gyno issues, even with dostinex. Some people aren't prone to it but just to be safe I would be weary of running both at the same time.
 
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