Here is how it works.
Cytadren is not an anabolic/androgenic steroid. Since it is a steroidbiosynthesial inhibitor it belongs to the group of sex hormones. Cytadren inhibits the build up of androgens, estrogens, and the suprarenal cortical hormones (glucocorticoids and mineralocorticoids).
Let us first take a look at the latter two points since they explain why athletes are interested in this compound. Cytadren has a highly anti estrogenic effect since, on the one hand, it inhibits the body's own estrogen production and, on the other hand, it obviates the conversion of androgens into estrogens. This is especially encouraging since it helps to keep the estrogen level of bodybuilders low. The second highly interesting point is that Cytadren prohibits the build up of adrenocortical hormones. It obviates the production of endogenous cortisone like no other compound by inhibiting the conversion of cholesterol into cortisone. For this reason, Cytadren, in school medicine, is used for the treatment of Cushing's syndrome, a hyperfunction of the adrenal glands which causes the body to overproduce cortisone. Consequently, it reduces the cortisone level, which has several advantages for the athlete. Cortisone is a catabolic hormone and catabolic is the exact opposite of anabolic. Cortisone prevents the protein synthesis in the muscle cell, resulting in a muscular atrophy by breaking down amino acids in the muscle cell.
The human body constantly releases cortisone and reacts to stress situations such as intense training by increasing its cortisone release. Natural bodybuilders, therefore, after a short time, experience a stagnation in their development since the release of the body's cortisone is higher than the anabolic effect of working out. The more advanced the athlete and the harder his workout, the more his cortisone level will increase.
If the release of cortisone can be successfully obviated or at least considerably reduced the ratio of anabolic hormones to catabolic hormones in the body shifts in favor of the former. This results in an increase in muscle mass and body strength. And Cytadren achieves exactly these results; however, there is one problem. Cytadren reduces the cortisone level so effectively that the body tries to balance this by hypophysially producing more ACTH (adenocorticotropic hormone), thus stimulating the secretion of cortisone by the adrenal glands. Thus in school medicine, when treating Gushing's syndrome, a low dose of oral hydrocortisone is used to prevent the hypophysis from producing ACTH. The dose is so low that the cortisone level in the blood does not rise substantially. And this is exactly the problem. Cytadren reduces the cortisone level which the body balances by producing ACTH, thus neutralizing the effect of Cytadren. If exogenous hydrocortisone is taken no ACTH is produced; however, this also reduces the effect of Cytadren. It is therefore necessary to find an administration schedule that prevents or delays the body's own production of ACTH. Since the body does not show abrupt reactions when the cortisone level is lowered by the intake of Cytadren, the compound must be taken over several days before the body begins reacting. If Cytadren is only taken for a period of two days and then discontinued for two entire days, it seems logical that the body will not have enough time to react accordingly, thus interrupting the production of ACTH in the hypophysis. Similar to Clenbuterol, analternating administration schedule with two days of administration and two days of abstinence is created.
RADAR