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Creatine...more than you thought it was

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Freelance Writer
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Creatine supplement may be helpful in certain muscular dystrophies (facioscapulohumeral dystrophy, Becker dystrophy, Duchenne dystrophy, sarcoglycan-deficient limb girdle muscular dystrophy). A placebo-controlled trial did not find evidence of a beneficial effect of creatine monohydrate on survival or disease progression in patients with ALS. Creatine has not found to be helpful in those with Myotonic Dystrophy Type 1.

Creatine has been found to increase strength and muscle mass in older adults who took 5 grams of creatine daily for 3 months. Creatine helps older individuals in their daily activities such as getting out of a chair. This nutrient may be helpful for memory enhancement in older individuals, but not in those who are young.

Creatine supplementation and cognitive performance in elderly individuals.
Neuropsychol Dev Cogn B Aging Neuropsychol Cogn. 2007 Sep; McMorris T, Mielcarz G, Harris RC, Swain JP, Howard A. School of Sport, Exercise and Health Sciences, University of Chichester, College Lane, Chichester, West Sussex PO19 6PE, UK.

The purpose of this study was to examine the effect of creatine supplementation on the cognitive performance of elderly people. Participants were divided into two groups, which were tested on random number generation, forward and backward number and spatial recall, and long-term memory tasks to establish a baseline level. Group 1 were given 5 g four times a day of placebo for 1 week, followed by the same dosage of creatine for the second week. Group 2 were given placebo both weeks. Participants were retested at the end of each week. Results showed a significant effect of creatine supplementation on all tasks except backward number recall. It was concluded that creatine supplementation aids cognition in the elderly.

Creatine monohydrate, a supplement sold to improve exercise performance, is being tested to see if helps those with Parkinson's disease. Early research suggests these supplements might be able to help slow the progression of Parkinson's, an incurable brain disorder that can slowly but steadily paralyze patients. The National Institute of Neurological Disorders and Stroke, one of the U.S. National Institutes of Health, is launching the trial as the first in a series of government-sponsored studies of new Parkinson's treatments. The NINDS will recruit 1,720 people with early-stage Parkinson's disease across the United States and Canada. Patients and doctors alike will not know whether they are getting creatine monohydrate or a placebo. The study is due to last three to five years. Creatine monohydrate may affect the mitochondria -- structures that produce energy inside cells. In mice, creatine was shown to prevent the loss of dopamine-producing brain cells. Palo Alto, California-based Avicena Group, Inc. will provide the purified creatine monohydrate for the trial. The company has also been testing creatine monohydrate against the nerve disorders Huntington's disease and amyotrophic lateral sclerosis, also known as ALS.


Vegetarians, particularly those who are on a strict lacto-ovo-vegetarian (LOV) diet do not ingest much creatine since this nutrient is mostly found in meats, fish, and chicken. Creatine helps muscles stay bulky and strong.

In a study published in the Journal of Sports Nutrition and Exercise Metabolism, thirty-two healthy men, who regularly consumed an omnivorous diet, were split into two groups. One group consumed a LOV diet while the other group had an omnivorous diet (they ate everything). The study lasted 26 days. In addition to their diet, on day 22 of the study, subjects were assigned in a double-blind manner to receive either creatine monohydrate 0.3 g per kilogram of body weight per day or an equivalent dose of placebo for 5 days. The results demonstrated that consuming a LOV diet for 21 days decreased muscle creatine concentration in individuals who normally consume meat and fish. However, the creatine content of muscle in the LOV group returned back to normal after a period of only 5 days.

Creatine, 5 g a day for six weeks, has been shown to improve brain performance (memory and intelligence) in adults who are vegetarian.

For more information go to: Creatine MH 1000
 
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