That's a tough one.If you accumulated a lot of estrogenic fat-patterning(pockets of adipose tissue),then it MIGHT help.BUT-you have to remember these are SELECTIVE estrogen receptor modulators,meaning they are not only selective in the tissues that they bind to,but selective in the acticity they display in these tissues.They can act anti-estrogenically in certain cells,and ESTROGENICALLY in others...I think you would be far better off lowering your overall Estrogen population with an aromitase inhibitor such as liquidex than using an item that simply blocks off certain sites but leaves the root of the problem intact.Just MO though.