I have two Ibanez and one Kramer.
Kramer (don't think they are even still around) only made one guitar that was any good - and that was the EVH varient. Mine wasn't that, and it sucked major ass - but it was good for tearing up and modding (the neck was too long and the radius wasn't correct on it - hence shitty play and strange sound).
I can't say enough good things about any of the Ibanez with a Wizard or Wizard 2 neck - those things fucking rock. I personally have a 540s (wanted the ltd, but this one is good enough - same pickups, just different fretboard).
if you have lots of cash, get a Paul Reed Smith - I would kill and maim for one of those...
if you want to be just like everyone else, get a strat or a les paul. if you get a strat - don't get a squire, and don't get anything made in anywhere but america (the mexican and japanese strats are total shit, but cost less).
basically if it costs under $500, then it will be shit - and that is a true $500 - there are places that you walk in a pick up a guitar and they say it is $800 and you laugh and say, I saw this shit for $300 in a catalog and they will be like... hmm, okay, $280 and its your's.
feel free to PM me if you want some more help.