If I remeber right, the half life of b6 is 8 hours, so you would have to take twice per day to keep levels constant. You would have to look up the brand on the time release that you our looking at to see how long it lasts. They only difference betwean the 2 would be how often you have to take it. Just like tren ace to tren cyp, ace is everyday shots or and the cyp once a week. If they made a tren cyp......