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aromasin dosage ?
- Thread starter mike1107
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lawnsaver
New member
mvmaxx said:25mg/EOD if your not too worried about gyno sides and that may cover it anyway. I'm a paranoid mofo so I run 25mg/ED.
But what about it having propeties to irriversably stop the aromatase enzyme?? Would we have to keep taking it?? Could be lower the dose the longer we take it?? I am curious on these aspects of aromasin
Zyg's initial post on Aromasin - now in "the best of Elite" shows that 25mg of Aromasin compares with 2.5mg of Femara and 1mg of Liquidex. After seeing other studies and other users experiences, as well as my own, I'd say that the Liquidex is absolutely no match for the Aromasin. I'm sure Liquidex will work in 90% of people that want to control estrogen but for me I'm looking for the ultimate protection. So far Aromasin has worked wonderful.
lawnsaver
New member
mvmaxx said:
I completely understand that the doses are comparable, but aromasin is not an aromatase inhibitor, it is an aromatse deactivator. It is said in a lot of medical abstracts that aromasin's actions are permenant. What I am trying to find out is, is there a point where we can lower the dose, or stop it all together?? We also need estrogen to grow, I wouldnt want to stop all estrogen production.
Do you understand what I am getting at??
This is something truely important to get a grip on.
I understand where you're going but I can't say I believe that aromasin is an aromatase deactivator for any length of time. I'm not doubting that it does this I just don't believe it continues with this operation for very long after stopping administration.
Case in point: I'm on Aromasin 25mg/ED with my prop/tren cycle. I already have a slight bit of preexisting gyno and so far it has not gotten worse at all. However, during my cycle I didn't take Aromasin for about 3 days and I did start to feel the gland getting sensitive. I threw in some Nolvadex for a few days and got back on the Aromasin. So far all has been good.
I just can't decide how long I should run it post cycle. Again, I'm taking all precautions during so I'm trying to do the same post cycle. But like you said estrogen is important and I feel I've been suppressing it for a long time.
Case in point: I'm on Aromasin 25mg/ED with my prop/tren cycle. I already have a slight bit of preexisting gyno and so far it has not gotten worse at all. However, during my cycle I didn't take Aromasin for about 3 days and I did start to feel the gland getting sensitive. I threw in some Nolvadex for a few days and got back on the Aromasin. So far all has been good.
I just can't decide how long I should run it post cycle. Again, I'm taking all precautions during so I'm trying to do the same post cycle. But like you said estrogen is important and I feel I've been suppressing it for a long time.
lawnsaver
New member
Ok, I found this info on Zyg's post!
After a single dose of exemestane 25 mg, the maximal suppression of circulating estrogens(98%), occurred 2 to 3 days after dosing and persisted for 4 to 5 days.
If this is the case, then we could easily take Aromasin every 3rd or 4th day. Correct? This would make aromasin a lot more cost effective. Again we do need estrogen for growth, so taking aromasin EOD might completely suppress our estrogen production, which can not be good.
Any thoughts??
After a single dose of exemestane 25 mg, the maximal suppression of circulating estrogens(98%), occurred 2 to 3 days after dosing and persisted for 4 to 5 days.
If this is the case, then we could easily take Aromasin every 3rd or 4th day. Correct? This would make aromasin a lot more cost effective. Again we do need estrogen for growth, so taking aromasin EOD might completely suppress our estrogen production, which can not be good.
Any thoughts??
LAWNSAVER said:
It's actually not an aromatase "deactivator", it's an irreversible (or suicidal) inhibitor. Reversible inhibitors like Femara and Arimidex can be "knocked off" the aromatase enzyme with an excess in aromatizing gear, hence the term "reversible". Aromasin cannot. The benefit for that is to be able to use 3g of test without worrying about E2 sides.
The reason I'm going to be using Aromasin next tren/prop cycle is a) it's easier on your lipid profile than Arimidex
b) 1mg of Arimidex ed still keeps my E2 levels at about 170% of pre-cycle on 50mg of fuckin' prop per day, as my bloodwork revealed.
CanadianBro
New member
LAWNSAVER said:
Very good questions LAWNSAVER
Aromasin is an irreversable aromatase inhibitor however people make the mistake and believe that once Aromasin is taken, the body cannot convert Androgen's to Estrogen permanently.
An important point is that Aromasin binds permanently with the aromatase enzyme, making it useless UNTIL the body actually replaces it through the normal metabolic attrition of enzymes.
With a single dose of exemestane 25 mg, the maximal suppression of circulating estrogens occurs 2 to 3 days after dosing and persists for 4 to 5 days.
Therefore, you can ideally take Aromasin every 2-3 days. There is really no point of taking it daily.
Also, you would not have to keep taking it or lowering the doage. Simply follow the usual treatment (1 pills/25mg EVERY 2 DAYS) throughout post-cycle therapy and 4-5 days after discontinuing, the Aromatase Enzyme binding site will no longer be occupied and the body will convert Androgen's to Estrogen the same way they did before.
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