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anyone use trisoleran
- Thread starter MIKERAZ
- Start date
macrophage69alpha
New member
several fair skinned associates found that it helped darken them but effects were not "amazing". though it did help them get relatively tan and they normally get a lot burnt and a little tan.
Zerxes
New member
I actually thought that they worked quite well, but I used the Mexican version, if that makes any difference. I took the advice of an article I had read about Trioxsalen, and tanned 1/2 of what I usually would. I(again imo) got alot darker than I normally would have in 1/2 the time spent tanning due to the pills. I took 20mgs two hours prior to tanning.
macrophage69alpha
New member
perhaps that could have been more clear.. it definitely works (as does methoxsalen..mexican version)..
just that if you are fair skinned it wont make you DARK.. it will speed tanning and somewhat enhance the "upper end" of acheivable darkness
just that if you are fair skinned it wont make you DARK.. it will speed tanning and somewhat enhance the "upper end" of acheivable darkness
macrophage69alpha
New member
Zerxes said:
yes the tradename is meladinina the drug is methoxsalen.. the drug in trisoralen is trioxasalen
macrophage69alpha
New member
HONSZ said:
agree.. though darker indivduals with the proper eyewear may be OK in "natural" sun
Dose it also increase your risk of skin cancer as well? This might be a way to try to get a script if not. If you have a few moles on your body you can tell the doc you want to be able to get a tan without staying in the sun for prolonged periods of time so as to avoid risking cancer.
Also can provide a link to an article(s) which may help outlining safe usage?
Also can provide a link to an article(s) which may help outlining safe usage?
macrophage69alpha
New member
=w= said:
it should DECREASE risk of skin cancer.. it increases melanin production
macrophage69alpha said:
There are other considerations Macro, which are too complex
to be discussed here.
Fonz
I.E> Fonz is not overly convinced about the safety of
melanin-enhancing compounds. See, they just don't
raise melanin levels, they also have an impact on epidermal layer
of your skin which CAN increase your risk of melanoma.
Fonz
macrophage69alpha
New member
EngiCream said:
unltraviolet dosage is much easier to control in a tanning bed.. go out side on a high UV day and well.. effects may not be desirable.. (though it will vary)
bodytemple75
New member
Re: anyone use trisoleran
I heave "heard" that some eldery seniors get it prescribed for when going out into the sun. Suppossed to help them deal w/ sun exposure. This is just what I have heard though... I have used "Oxsoralen." This is included in the psoralens family. (Melindinina, Trioxsoralen, ect...) Treatment for Vitiligo. (skin pigmentation disorder) The only negatives I have heard were to watch your dose, and too much can hurt your eyes, and you may get a bad burn, if in the real sun too long. This is ue to "overexposure" of Uv light. I have used, and never had any problems. It was always good. It has made me the most tan I have ever been (without paint on tans) and I have never slightly even burned with using it. My eyes are fine, just take precaution, and understand it is a Rx before you use. BTW,... LIFE R------- carries it. (So I understand)
Feel free to pm me for details on another.
I heave "heard" that some eldery seniors get it prescribed for when going out into the sun. Suppossed to help them deal w/ sun exposure. This is just what I have heard though... I have used "Oxsoralen." This is included in the psoralens family. (Melindinina, Trioxsoralen, ect...) Treatment for Vitiligo. (skin pigmentation disorder) The only negatives I have heard were to watch your dose, and too much can hurt your eyes, and you may get a bad burn, if in the real sun too long. This is ue to "overexposure" of Uv light. I have used, and never had any problems. It was always good. It has made me the most tan I have ever been (without paint on tans) and I have never slightly even burned with using it. My eyes are fine, just take precaution, and understand it is a Rx before you use. BTW,... LIFE R------- carries it. (So I understand)
Feel free to pm me for details on another.
bodytemple75
New member
Re: anyone use trisoleran
Great well known place for non controlled meds, as Oxsoralen....
This place, I have nothing but good to say. Excellent CS.
Great well known place for non controlled meds, as Oxsoralen....
This place, I have nothing but good to say. Excellent CS.
bodytemple75
New member
Psoralen Family information.
Psoralen and UVA light therapy (PUVA) for psoriasis
Examples
Psoralens
Pills, lotions, or bath salts
methoxsalen
A psoralen medication is taken 1 1/2 to 2 hours before you are exposed to ultraviolet A (UVA) light (PUVA). This treatment is repeated 2 to 3 times a week. The dose of medication is not increased, but the amount of light may be increased.
Goggles should be worn to protect eyes during UVA treatment. Special UVA-blocking glasses should be worn for 24 hours after PUVA therapy. Men should protect their genitals from UVA exposure during treatments.
Psoralens may also be used in a form that can be put into your bath water. This form causes greater sensitivity to UVA than the oral medication, so lower doses of UVA can be used.
How It Works
Psoralens increase the skin's sensitivity to UV light, including sunlight. They are used to improve the effectiveness of UV light therapy for psoriasis.
It is thought that PUVA therapy reduces the excess growth of skin cells. It also weakens the immune system.
Why It Is Used
PUVA is used to treat moderate to severe psoriasis (covering more than 20% of the skin).
PUVA is used to treat psoriasis that has not responded to creams, ointments, or tar products used with UV exposure (phototherapy). It should be used in the lowest doses possible. Higher doses and more exposure increase the risk of skin cancer.
Psoralens should not be used by:
Children under age 12, because the UV light therapy may cause cataracts.
People who have diseases that make their skin more sensitive to sunlight (such as lupus).
Fertile men and women who do not use birth control. There is a small risk of birth defects.
Pregnant women, because of possible effects on developing fetuses. How Well It Works
Many studies have shown that PUVA is effective in treating psoriasis.1
In most cases, the skin clears after 20 to 30 treatments.
Side Effects
Short-term side effects when using PUVA to treat psoriasis include:
Skin redness, headache, nausea, itching.
Burns.
The spread of psoriasis to skin that was not affected before (Koebner's response).
Nausea from the medication. The most significant potential long-term effect of PUVA treatment is squamous cell carcinoma, a type of skin cancer. PUVA treatments with cyclosporine have shown a significant increase in the risk of squamous cell cancer.2
The male genitals are highly susceptible to the cancer-causing effects of both PUVA and UVB therapy. High levels of exposure to UVB carry a higher risk of genital cancers than low levels. Female genitals do not seem to be affected.
Other long-term side effects when using PUVA to treat psoriasis include:
Premature skin damage associated with sun exposure.
Discolored spots on the skin.
Overgrowth of the scaly layer of skin caused by exposure to sunlight (actinic keratosis).
Nonmelanoma skin cancer.
Cataracts. Cataracts may be avoided by wearing sunglasses that block UV light when outdoors. See Drug Reference for a full list of side effects. (Drug Reference is not available in all systems.)
What to Think About
Psoralens applied to the skin (topical) may help to avoid some side effects of PUVA. They may be especially helpful when psoralens taken by mouth (oral) causes severe nausea. Topical psoralens may be used for psoriasis that affects only a small part of the skin.
Topical psoralens, such as those given in bath water, are as effective as oral psoralens. However, if light treatments are given in a doctor's office, they may be less convenient.
See a list of questions to ask your doctor about medications.
Author: Kerry V. Cooke
Kathleen M. Ariss, MS
Last Updated February 28, 2002
Medical Review: Adam Husney, MD - Family Practice
Randall D. Burr, MD - Dermatology
© 1995-2003, Healthwise, Incorporated, P.O. Box 1989, Boise, ID 83701. ALL RIGHTS RESERVED.
Additional:
**As far as I understand it,(psoralens)...although some may vary in strength, they are basically all the same, and are just used under different brand names.
Drugs known as psoralens cause the skin to be excessively sensitive to sunlight. Psoralens include Oxsoralen (methoxsalen or 8-MOP) and Trisoralen (trioxsalen). In addition, some antibiotics such as ciprofloxacin and tetracycline may make the skin more likely to sunburn. If St. John?s wort, which also sensitizes the skin to light, is taken at the same time as another of these sun-sensitizing drugs, the chance of sunburn increases.
Psoralen and UVA light therapy (PUVA) for psoriasis
Examples
Psoralens
Pills, lotions, or bath salts
methoxsalen
A psoralen medication is taken 1 1/2 to 2 hours before you are exposed to ultraviolet A (UVA) light (PUVA). This treatment is repeated 2 to 3 times a week. The dose of medication is not increased, but the amount of light may be increased.
Goggles should be worn to protect eyes during UVA treatment. Special UVA-blocking glasses should be worn for 24 hours after PUVA therapy. Men should protect their genitals from UVA exposure during treatments.
Psoralens may also be used in a form that can be put into your bath water. This form causes greater sensitivity to UVA than the oral medication, so lower doses of UVA can be used.
How It Works
Psoralens increase the skin's sensitivity to UV light, including sunlight. They are used to improve the effectiveness of UV light therapy for psoriasis.
It is thought that PUVA therapy reduces the excess growth of skin cells. It also weakens the immune system.
Why It Is Used
PUVA is used to treat moderate to severe psoriasis (covering more than 20% of the skin).
PUVA is used to treat psoriasis that has not responded to creams, ointments, or tar products used with UV exposure (phototherapy). It should be used in the lowest doses possible. Higher doses and more exposure increase the risk of skin cancer.
Psoralens should not be used by:
Children under age 12, because the UV light therapy may cause cataracts.
People who have diseases that make their skin more sensitive to sunlight (such as lupus).
Fertile men and women who do not use birth control. There is a small risk of birth defects.
Pregnant women, because of possible effects on developing fetuses. How Well It Works
Many studies have shown that PUVA is effective in treating psoriasis.1
In most cases, the skin clears after 20 to 30 treatments.
Side Effects
Short-term side effects when using PUVA to treat psoriasis include:
Skin redness, headache, nausea, itching.
Burns.
The spread of psoriasis to skin that was not affected before (Koebner's response).
Nausea from the medication. The most significant potential long-term effect of PUVA treatment is squamous cell carcinoma, a type of skin cancer. PUVA treatments with cyclosporine have shown a significant increase in the risk of squamous cell cancer.2
The male genitals are highly susceptible to the cancer-causing effects of both PUVA and UVB therapy. High levels of exposure to UVB carry a higher risk of genital cancers than low levels. Female genitals do not seem to be affected.
Other long-term side effects when using PUVA to treat psoriasis include:
Premature skin damage associated with sun exposure.
Discolored spots on the skin.
Overgrowth of the scaly layer of skin caused by exposure to sunlight (actinic keratosis).
Nonmelanoma skin cancer.
Cataracts. Cataracts may be avoided by wearing sunglasses that block UV light when outdoors. See Drug Reference for a full list of side effects. (Drug Reference is not available in all systems.)
What to Think About
Psoralens applied to the skin (topical) may help to avoid some side effects of PUVA. They may be especially helpful when psoralens taken by mouth (oral) causes severe nausea. Topical psoralens may be used for psoriasis that affects only a small part of the skin.
Topical psoralens, such as those given in bath water, are as effective as oral psoralens. However, if light treatments are given in a doctor's office, they may be less convenient.
See a list of questions to ask your doctor about medications.
Author: Kerry V. Cooke
Kathleen M. Ariss, MS
Last Updated February 28, 2002
Medical Review: Adam Husney, MD - Family Practice
Randall D. Burr, MD - Dermatology
© 1995-2003, Healthwise, Incorporated, P.O. Box 1989, Boise, ID 83701. ALL RIGHTS RESERVED.
Additional:
**As far as I understand it,(psoralens)...although some may vary in strength, they are basically all the same, and are just used under different brand names.
Drugs known as psoralens cause the skin to be excessively sensitive to sunlight. Psoralens include Oxsoralen (methoxsalen or 8-MOP) and Trisoralen (trioxsalen). In addition, some antibiotics such as ciprofloxacin and tetracycline may make the skin more likely to sunburn. If St. John?s wort, which also sensitizes the skin to light, is taken at the same time as another of these sun-sensitizing drugs, the chance of sunburn increases.
bodytemple75
New member
Re: anyone use trisoleran
Hope I helped.
GL
PM me if you need any add. info I may be able to help you with.
Hope I helped.
GL
PM me if you need any add. info I may be able to help you with.
