I prefer Glute shots, never had a problem there so for. Twisting round is a bit of a pain, especially if your guage needles a bit thin and it takes a long time / pressure to shove it all in. Tip for newbies that are a bit scared of needles and are sticking to orals, get a shower head spray and spray the area with cold water for a couple of mins before injecting. It numbs the area so you hardly feel a thing. The shock of the cold water that takes your breath away is far worse than the actual injection !!