Flexed, I did some input on this at the anabolic board.
Davey, answer for your question depends on the disease that is affecting pancreas. Most common is its acute inflammation, pancreatitis, and the most common symptom associated to that is pain. Usually very intense, crossing midsection , and aleviates when tha patient bends. Sometimes pain is so intense that patients assume the maometan( muslim) praying position.Other than pain, intense nausea and vomiting.
Chronic pancreatitis usually present pain and digestion disorders, like diarrhea.Glucose intolerance can develop as a sign of pancreatic failure to produce insulin.
Cancer can present all the above plus very severe weight loss.