The one point is that before A A S substitution in this study, all men were clearly hypogonadal:
Androgen substitution led to no significant increase of serum Testosterone in the proviron group
5 alpha-Dihydrotestosterone significantly increased in all treatment groups compared with baseline.
Compared with presubstitution levels, a significant increase of TOTAL CHOLESTEROL was observed in all treatment groups (18.8% +/- 2.5%)
Low-density lipoprotein cholesterol (LDL-C) also increased significantly by 46.4% +/- 4.1%
High-density lipoprotein cholesterol (HDL-C) showed a significant decrease by -34.9% +/- 2.5%
Serum Triglycerides significantly increased by 46.4% +/- 10.3%