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Research Chemical SciencesUGFREAKeudomestic
napsgeargenezapharmateuticals domestic-supplypuritysourcelabsResearch Chemical SciencesUGFREAKeudomestic

Anabolics and Protein Digestion

Primo57

New member
Part #1

Is it possible that anabolics also increase protein utilization at the level of the GI system? Here's my wild guess: In addition to increased transcription for muscle tissue, there is also increased transcription (and translation) for the proteases trypsinogen, chymotrypsinogen, and procarboxypeptidase, which are released by the pancreas. These precursors are secreted into the small intestine and subsequently activated by enterokinase. The result is more amino acids for our utilization. The limiting factor is the Na-cotransport system in the microvilli.

Part #2 Steroids may suppress the enterogastric reflex

The presence of large amounts of protein in the small intestine causes inhibition (feed back) of gastric motility, signaled by gastric inhibitory peptide, secretin, and somatostatin. It may be possible that certain anabolics
downregulate these compounds enabling more protein
to move to the stomach at a faster rate for digestion.

Physiology is confusing as hell, and everything is tied
together, so this is just a thought
 
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