Acne all you need to know.

[ryker77]

A / T / S

Company
Medicis

Pharmacologic Class
Macrolide antibiotic.

Generic Name
Erythromycin

Available as
A/T/S SOLUTION
(erythromycin 2%, alcohol 66%)
A/T/S GEL
(erythromycin 2%, alcohol 92%)

Indications
Acne vulgaris.

Adults
Solution: Apply with applicator or pad to cleansed area twice daily.
Gel: Apply sparingly to cleansed area twice daily.

Children
Not applicable.

Contraindications
Although not explicitly stated, hypersensitivity to this drug, to others in
its class, to related drugs, or to any of its excipients, is assumed to be
a contraindication.

Precautions
Avoid eyes and mucous membranes. Pregnancy (Category B).
Nursing mothers: Not recommended.

Interactions
Additive irritation with other topical agents (esp. abrasives or keratolytics).

Adverse Reactions
Superinfection, dryness, scaly skin, pruritus, urticaria, erythema, oiliness, burning sensation.

How Supplied

Soln–60mL
Gel–30g

 

[ryker77]

ACCUTANE

Company
Roche

Pharmacologic Class
Retinoid.

Generic Name
Isotretinoin

Available as
Isotretinoin 10mg, 20mg, 40mg; capsules; contains parabens.

Indications
Severe recalcitrant nodular acne unresponsive to conventional therapy, including systemic antibiotics.

Adults
Take with meals. 0.5-1mg/kg per day in 2 divided doses; treat for 15-20 weeks or less if nodule count reduced by >70%; max 2mg/kg per day. Repeat course only if necessary after at least 2 months drug-free interval.

Children
Not applicable.

Contraindications
Pregnancy (Category X). Nursing mothers. Although not explicitly stated, hypersensitivity to this drug, to others in its class, to related drugs, or to any of its excipients, is assumed to be a contraindication.

Precautions
Be fully familiar with drug's toxicity before use. Counsel patient about need for contraception; obtain 2 negative pregnancy tests prior to initiation of drug and monthly thereafter; use 2 effective methods of contraception 1 month before, during, and 1 month after therapy; get written informed consent. Monitor blood lipids initially and for 1st 4 weeks. Osteoporosis risk (eg, osteomalacia, anorexia nervosa). Monitor bone growth, glucose, sed rate, CBC, liver enzymes. Discontinue if visual or auditory disturbances; colitis, pancreatitis or hepatitis symptoms; uncontrolled hypertriglyceridemia, or significant decrease in WBCs occurs. Refer to specialist if papilledema or hearing disturbances occurs. Do not donate blood during and for 1 month after therapy. Avoid wax epilation or skin resurfacing during and for 6 months after therapy. Adolescents. Avoid sun, UV light. Decreased tolerance to contact lenses. Max 1 month/Rx.

Interactions
Avoid tetracyclines (increased risk of pseudotumor cerebri), Vit. A, or alcohol consumption. Avoid St. John's wort with hormonal contraceptives. Low-dose progestin-only contraceptives (ie, minipills) may provide inadequate contraception. Caution with drugs that can disturb bone metabolism (eg, anticonvulsants, systemic corticosteroids).

Adverse Reactions
Dry skin, eyes, nose, mouth, and lips, transient exacerbation of acne, dizziness, drowsiness, headache, abnormal menses, bronchospasm, voice alterations, alopecia, epistaxis, flushing, hirsutism, rash, GI disturbances, photosensitivity, abnormal wound healing, depression, psychosis, suicidal ideation, pseudotumor cerebri, pancreatitis; visual, auditory, or lipid disturbances; hepatotoxicity, inflammatory bowel disease, osteopenia, osteoporosis, hyperostosis, premature epiphyseal closure, reversible corneal opacities, decreased night vision, musculoskeletal symptoms (eg, arthralgia), back/chest pain, blood dyscrasias, glucose intolerance, palpitation, thrombotic disease.

How Supplied
Caps–10 x 10 (Rx packs)

 

[ryker77]

ACHROMYCIN V

Company
Stada

Pharmacologic Class
Tetracycline antibiotic.

Generic Name
Tetracycline

Available as
Tetracycline HCl 250mg, 500mg; capsules.

Indications
Adjunct in severe acne.

Adults
Initially 1g daily in 2-4 divided doses, then 125-500mg daily.

Children
Not applicable.

Contraindications
Although not explicitly stated, hypersensitivity to this drug, to others in
its class, to related drugs, or to any of its excipients, is assumed to be
a contraindication.

Precautions
Renal impairment. Monitor blood, renal and liver function in long-term use. Sun or UV light. Pregnancy, Nursing mothers: Not recommended.

Interactions
Avoid methoxyflurane, photosensitizing agents. May antagonize bactericidal antibiotics. May increase serum digoxin levels. Reduced absorption with antacids, iron, zinc, calcium, magnesium, dairy products, urinary alkalinizers, other multivalent cations. May reduce effectiveness
of oral contraceptives. Monitor prothrombin time with oral anticoagulants.

Adverse Reactions
Nausea, dizziness, rash, blood dyscrasias, pseudotumor cerebri, photosensitivity, increased BUN, hepatotoxicity.

How Supplied
Caps: 250mg–40, 100, 1000
500mg–100, 1000

 

[ryker77]

AVITA

Company
Bertek

Pharmacologic Class
Retinoid.

Generic Name
Tretinoin

Available as
Tretinoin 0.025%; cream; gel.

Indications
Acne vulgaris.

Adults
Apply sparingly to cleansed and completely dry skin once daily
at bedtime. If irritation develops, may reduce the dosing frequency.

Children
Not applicable.

Contraindications
Although not explicitly stated, hypersensitivity to this drug, to others in
its class, to related drugs, or to any of its excipients, is assumed to be
a contraindication.

Precautions
Not for use in eczema or on sunburned skin.
Minimize exposure to sun, UV light, weather extremes.
Avoid eyes, mouth, angles of nose, mucous membranes.
Pregnancy (Category C) Nursing mothers: Not recommended.

Interactions
Allow effects of benzoyl peroxide, sulfur, resorcinol, salicylic acid, other topical acne agents to subside before applying. Avoid keratolytics, abrasives, astringents, drying agents, high-alcohol content topical products, spices, lime.

Adverse Reactions
Apparent exacerbation of symptoms, local skin reactions
(including erythema, edema, blistering, crusting), transient
pigmentation changes, stinging on application, dry skin.

How Supplied
Cream, gel–20g, 45g

 

[ryker77]

AZELEX

Company
Allergan Herbert

Pharmacologic Class
Antibacterial/keratolytic.

Generic Name
Azelaic acid

Available as
Azelaic acid 20%; cream.

Indications
Mild to moderate inflammatory acne vulgaris.

Adults
Wash and dry skin. Massage thin film gently into affected areas twice daily (AM and PM). Wash hands after use. If persistent irritation occurs, may decrease to once daily.

Children
Not recommended.

Contraindications
Although not explicitly stated, hypersensitivity to this drug, to others in its class, to related drugs, or to any of its excipients, is assumed to be a contraindication.

Precautions
Monitor patients with dark complexions for hypopigmentation. Discontinue if sensitivity or severe irritation develops. Avoid mouth, eyes, other mucous membranes, and occlusive dressings. Pregnancy (Category B). Nursing mothers.

Adverse Reactions
Pruritus, burning, stinging, tingling; rare: exacerbation of asthma or of recurrent herpes labialis, vitiligo depigmentation, small depigmented spots, hypertrichosis, reddening.

How Supplied
Crm–30g, 50g

 

[ryker77]

BENZAC

BENZAC
Company
Galderma

Pharmacologic Class
Antibacterial/keratolytic.

Generic Name
Benzoyl peroxide

Available as
Benzoyl peroxide 5%, 10%, alcohol 12%; gel.

Indications
Acne.

Adults
Initially apply to cleansed area once daily, increase to 2-3 times daily
as tolerated.

Children
Not recommended.

Contraindications
Although not explicitly stated, hypersensitivity to this drug, to others in
its class, to related drugs, or to any of its excipients, is assumed to be
a contraindication.

Precautions
Avoid eyes, mouth, and mucous membranes.
Pregnancy (Category C). Nursing mothers.

Interactions
PABA sunscreens may transiently discolor skin.

Adverse Reactions
Excessive drying, allergic dermatitis, may bleach fabrics or hair.

How Supplied
Gel–60g

 

[Frackal]

Alpha Lipoic acid, both the racemic and r version helped quite a bit with my acne. So does an EFA supplement to keep skin smooth. Face acne here.

 

[ryker77]

BENZAC-W

BENZAC-W

Company
Galderma

Pharmacologic Class
Antibacterial/keratolytic.

Generic Name
Benzoyl peroxide

Available as
BENZAC-W GEL
(benzoyl peroxide 2.5%, 5%, 10%; aqueous-base gel)
BENZAC-W WASH
(benzoyl peroxide 5%, 10%; cleansing solution)

Indications
Acne.

Adults
Gel: Initially apply to cleansed area once daily,
increase to 2-3 times daily as tolerated.
Wash: Wash affected area 1-2 times a day. Rinse off.

Children
Not applicable.

Contraindications
Although not explicitly stated, hypersensitivity to this drug, to others in its class, to related drugs, or to any of its excipients, is assumed to be a contraindication.

Precautions
Avoid eyes, mouth, and mucous membranes. Pregnancy
(Category C). Nursing mothers.

Interactions
PABA sunscreens may transiently discolor skin.

Adverse Reactions
Excessive drying, allergic dermatitis, may bleach fabrics or hair.

How Supplied
W Gel–60g
Wash 5%–4oz, 8oz
10%–8oz

 

[ryker77]

BENZACLIN

BENZACLIN
Company
Dermik

Pharmacologic Class
Lincosamide antibiotic + antibacterial/keratolytic.

Generic Name
Clindamycin + Benzoyl peroxide

Available as
Clindamycin (as phosphate) 1%, benzoyl peroxide 5%; gel.

Indications
Topical treatment of acne vulgaris.

Adults
Apply twice daily.

Children
Not recommended.

Contraindications
History of regional enteritis, ulcerative or antibiotic-associated colitis.

Precautions
Avoid eyes, mucous membranes. Discontinue if significant diarrhea occurs. Pregnancy (Category C). Nursing mothers: Not recommended.

Interactions
Additive irritation with other topical agents. Avoid erythromycin.

Adverse Reactions
Dry skin, application site reaction, pruritus, peeling, erythema, sun-burn; superinfection, colitis (rare); may bleach fabrics or hair.

How Supplied
Gel-25g, 50g

 

[ryker77]

BENZAGEL

BENZAGEL
Company
Dermik

Pharmacologic Class
Antibacterial/keratolytic.

Generic Name
Benzoyl peroxide

Available as
BENZAGEL
(Benzoyl peroxide 5%, 10%; alcohol 14%; gel)
BENZAGEL WASH
(Benzoyl peroxide 10%; alcohol 14%; gel)

Indications
Mild to moderate acne.

Adults
Benzagel: Apply sparingly to cleansed and dried area one or more times daily,
as tolerated. Benzagel Wash: Wet skin, wash affected area(s) once or twice daily.
Rinse, pat dry.

Children
Not recommended.

Contraindications
Although not explicitly stated, hypersensitivity to this drug, to others in
its class, to related drugs, or to any of its excipients, is assumed to be
a contraindication.

Precautions
Avoid eyes, mouth, and mucous membranes.
Discontinue Gel if severe irritation occurs; discontinue Wash if itching, redness, burning, swelling, or undue dryness occurs. May bleach fabrics or hair. Pregnancy (Category C). Nursing mothers.

Interactions
PABA sunscreens may transiently discolor skin.

Adverse Reactions
Excessive dryness, allergic or contact dermatitis,
may bleach fabrics or hair.

How Supplied
Benzagel–1.5oz
Benzagel Wash–60g