Curious about this myself. I just got two of these HCG (HUCOG) 5000's in today, and I was wondering the same thing since they appear to be pre-mixed. They're sealed in a plastic & foil pack, but I see liquid in the vials not powder. I wasn't expecting pre-mixed hcg, so I'm a little worried about the quality. It's been 22 days since they shipped it out, and it's the hottest time of year where I'm from.