say no more.. if u are taking 250 mg dosis then 1 shot per week ,, if u are taking 500mg split it out 250 / 250 every 4 days . And if u are taking over 750 MG then u should split it out on 3 dosis. and if ur case is like mine .. 375Mg os Sust on 1 shot (1.5CC) u should be OK