Tren and immunity crash (hpv warts !) - any way to avoid it ?

[CpenDoc7]

If the immune system issue is elevated histamine , I would go with 2grams of methionine instead of vitamin C. Vitamin C does a mediocre job in clearing histamine from the blood. Methionine does a much better job.

*edit*
Since methionine can be oxidized into homo cysteine , one can use trimethylglycine to convert the homo cysteine back into methionine
*edit*

Good stuff will check this out also.....
I guess allot of people do c because of cost....$7 per pound
This will give me something to read into today.....appreciate it.

 

[CpenDoc7]

Abstract
Persistent oncogenic human papillomavirus (HPV) infection is associated with cervical dysplasia. Cofactors, such as nutrient status, may be required for the progression of HPV infection to neoplasia. HPV DNA methylation patterns in vitro have been shown to be associated with viral transcriptional activity. Folate, vitamin B12, vitamin B6, and methionine may function to prevent cervical cancer through their role in DNA methylation. This study was conducted to examine the relationship of dietary intake of folate, vitamin B12, vitamin B6, and methionine, as well as circulating levels of folate and vitamin B12 to HPV persistence. Oncogenic HPV status was determined at baseline and at approximately 3 and 9 months postbaseline. Multivariate logistic regression analysis was used to determine the adjusted odds ratios for persistent HPV infection associated with each tertile of individual nutrient among 201 women with a persistent or intermittent HPV infection. Circulating vitamin B12 levels were inversely associated with HPV persistence (P for trend, 0.037) after adjusting for age, age at first intercourse, marital status, cigarette smoking status, race, and body mass index. In addition, women with circulating levels in the highest tertile (>493.2 pg/ml) of vitamin B12 were less likely to have a persistent infection (adjusted odds ratio = 0.4; 95% confidence interval = 0.17-0.96). No significant associations were observed between HPV persistence and dietary intake of folate, vitamin B12, vitamin B6, or methionine from food alone or from food and supplements combined or from circulating folate. These data suggest a role for circulating vitamin B12 in early cervical carcinogenesis.


Survey says let's not forget B12

 

[CpenDoc7]

Abstract
Conventional chemotherapies have showed their limits, notably for patients with advanced cancer. New therapeutic strategies must be identified, and the metabolic abnormalities of cancer cells offer such opportunities. Many human cancer cell lines and primary tumors have absolute requirements for methionine, an essential amino acid. In contrast, normal cells are relatively resistant to exogenous methionine restriction. The biochemical mechanism for methionine dependency has been studied extensively, but the fundamental mechanism remains unclear. A number of investigators have attempted to exploit the methionine dependence of tumors for therapeutic effects in vivo. To reduce in vivo methionine in plasma and tumours, dietary and pharmacological treatments have been used. Methionine-free diet or methionine-deprived total parenteral nutrition causes regression of a variety of animal tumours. Alternatively, methionine depletion was achieved by the use of methioninase. This enzyme specifically degrades methionine and inhibits tumour growth in preclinical models. Because of potential toxicity and quality of life problems, prolonged methionine restriction with diet or with methioninase is not suitable for clinical use. Methionine restriction may find greater application in association with various chemotherapeutic agents. Several preclinical studies have demonstrated synergy between methionine restriction and various cytotoxic chemotherapy drugs. The experimental results accumulated during the last three decades suggest that methionine restriction can become an additional cancer therapeutic strategy, notably in association with chemotherapy.

Methionine makes me a little nervouse

 

[CpenDoc7]

3,3-Diindolylmethane is a dietary indole from cruciferous vegetables that has demonstrated pre-clinical therapeutic efficacy in models of DMBA-induced mammary cancer, transplanted human Breast Cancer , and in models of human papilloma virus (HPV) related disease.

Animal and human use of crystalline diindolylmethane has revealed the need for absorption-enhancing technology to allow adequate gastro-intestinal uptake. BioResponse-DIM, a patented formulation of diindolylmethane categorized and sold as a dietary supplement, utilizes solubility-enhancing micro-encapsulation technology to allow absorption of effective amounts of diindolylmethane.

Human use of this formulation promotes a dose-responsive upward effect on the urinary ratio of 2-OH/16-OH estrone metabolites, demonstrated by ELISA testing of urine before-and-after use. In previous prospective studies, a greater 2-OH/16-OH estrone urinary ratio has been associated with a lowered risk of future breast cancer. We are able to monitor compliance by measurement of urinary diindolylmethane using gas chromatography-mass spectrometry.

Human use of this preparation at higher doses has demonstrated treatment-related resolution of moderate and severe cervical dysplasia in preliminary open-label testing. A still higher dose, about 10 times above that possible from dietary exposure to diindolylmethane from vegetable sources, has resulted in the control of laryngeal papillomas and resolution of cutaneous and plantar warts in preliminary human testing. The clearing of HPV-related lesions is consistent with diindolylmethane's previously described, apoptosis-promoting and chemopreventive activity.

 

[CpenDoc7]

Definitely digging colloidal silver......fascinating history I'm in. Best source?