They can take it. I've heard mixed results on hgh frag, there are better choices out there. But if you are set on using it, she can start at 200mcg, 3x per day, moving up to 200mcg 5x per day. (Hope you don't mind a lot of injections) It has to be taken away from food, (fasted). I know some people who just dose it in the morning before fasted cardio. Like I said earlier, if she's taking it just for fat loss, there are better choices that are easier to administer.