Will nolvadex help preventing oxy Gyno

[GOD_HERCULES]

My friend is taking 50mg Oxy a day. He is getting sore nipples. Will 20mg nolvadex help preventing bitch tits.

Thanks

 

[bazilbb]

yes it will help for sure. use 40mg/day until syptoms disappear.

 

[GOD_HERCULES]

That's what I thought but after I read this article from Bill Roberts I am afraid to give my good friend advise... Because Bill Roberts says that Oxy induced gyno is progestagenic.

by Bill Roberts - Like methandrostenolone (Dianabol), oxymetholone does not bind well to the androgen receptor (AR), and most of the anabolism it provides is via non-AR-mediated effects. It is therefore a Class II steroid and is best stacked with a Class I steroid. The drug appears to give the same benefits as Dianabol. Unlike Dianabol, however, it seems that oxymetholone is progestagenic. It has been observed to cause nipple soreness or to aggravate gynecomastia even in the presence of high dose antiestrogens, strongly suggesting that the effect is not estrogenic. That effect can be reduced by concurrent use of stanozolol (Winstrol), which is anti-progestagenic. This progestagenic effect of oxymetholone is only a concern when using aromatizing steroids. With androgens such as Primobolan, oxymetholone stacks very nicely and is a surprisingly friendly drug. In contrast, with testosterone it is a very harsh drug.

Anadrol does not convert to estrogen, and thus antiestrogens are not required if no aromatizable AAS are being used. However, in concert with aromatizing drugs, Anadrol is notorious for worsening "estrogenic" symptoms, possibly by producing progestagenic symptoms which the bodybuilder confuses as estrogenic, or by altering estrogen metabolism, or by upregulating aromatase.

Compared to what bodybuilders expect of it, the drug is reasonably mild when no aromatizing steroids are present. I consider its potency approximately comparable to Dianabol. It is not unusual for a first time user to do quite well on an Anadrol-only cycle, but more advanced users will want to stack with another steroid. Typical use is 50-150 mg/day, which should be divided into several doses per day.

Because oxymetholone is 17-alkylated, it is stressful to the liver. It is better to limit use to no more than 6 weeks or preferably four weeks before taking a break of at least equal length. Many users feel that it is more effectively used in the beginning parts of the cycle, rather than in the last few weeks.

 

[Dutch windmill]

My friend is taking 50mg Oxy a day. He is getting sore nipples. Will 20mg nolvadex help preventing bitch tits.

Thanks

Hi buddy yes Nolvadex should help, but double the dose to 40 mgs/day. It will hinder the gains of oxy due that oxys gets a lot of the effect from the raise in oestrogen..

Good luck bro!

D.W.

 

[Ulter]

No it won't help.

 

[Dutch windmill]

Lots of contradicting opinions that i see here.

It has been suggested that the estrogenic effects of oxymetholone may not be as much mediated by estrogen, as by oxymetholone itself activating the estrogen receptor. Because there is little to no aromatisation off oxymetholone, the possible progestational effect was examined first. Similar to that of nandrolone perhaps. But a study2 testing the progestational effects of oxymetholone and methandrostenolone against those of testosterone as well as nandrolone and its metabolites showed that the progestagenic activity of oxymetholone wasn't even in the neighbourhood of that of testosterone, let alone nandrolone. Ruling out the possibility of progestagenic activity and aromatisation, that only left oxymetholone engaging in a structure with the estrogen receptor itself. Since it has an A-ring similar to that of estradiol (the prime estrogen) so this would be the most logical explanation. Since progesterone acts as an estrogen agonist, it would require circulating estrogen to negotiate such levels of water build-up as oxymetholone causes, so it seemed like a far-fetched idea to begin with.

In terms of secondary drugs, I wish I had a lot to recommend here, but really there isn't much to be helped with oxymetholone. Even with liver protection it would still do serious damage and with every bit of added protection, the efficacy rate of oxymetholone would go down. As for estrogen maintenance, Nolvadex being the strongest of estrogen receptor antagonists comes highly recommended and preferably in higher than normal doses, 30-40 mg, as its oxymetholone itself that is the culprit and not its aromatized form. On the other hand, we need to take into account that more than half of Anadrol's anabolic action stems from this estrogenic action as well. So its sort of trading less side-effects for gains. One thing that is advised is blood pressure medication as extreme hypertension has been noted. And I'll say it a third and last time, its best to get regular liver check-ups when taking Anadrol.

References

1 Reeves RD, Morris MD, Barbour GL., Hyperlipidemia due to oxymetholone therapy. Occurrence in a long-term hemodialysis patient., JAMA 1976 Aug 2;236(5):469-72

2 Desausles PA, Les hormones anabolisantes de point de vue experimental (Anabolic hormones from an experimental viewpoint), Helv. Med. Acta 1960 , 479-503

3 Molinari PF, Neri LL., Effect of a single oral dose of oxymetholone on the metabolism of human erythrocytes., Exp Hematol 1978 Sep;6(8):648-54

4 Pavlatos AM, Fultz O, Monberg MJ, Vootkur A, Pharmd., Review of oxymetholone: a 17alpha-alkylated anabolic-androgenic steroid, Clin Ther 2001 Jun;23(6):789-801; discussion 771

5 Woodard TL, Burghen GA, Kitabchi AE, Wilimas JA., Glucose intolerance and insulin resistance in aplastic anemia treated with oxymetholone., J Clin Endocrinol Metab 1981 Nov;53(5):905-8




Quite confusing subject brothers..

D.W.

 

[GOD_HERCULES]

Yep! That's why I am posting this question.

So bump for somebody with a answer.

 

[bazilbb]

answer is that nolva will help greatly with Oxy gyno. as it has affinity to ER on its own, but when nolva is there already and is bound to it strongly, it wont let mlecule of Oxy exert its action......

 

[juicetothegills]

it will help by friend you mean you

 

[SOLID]

good info, but confusing to see diferent opionions and studies. Where do you get these Bill Roberts article's I see posted every so often?

 

[hhajdo]

good info, but confusing to see diferent opionions and studies. Where do you get these Bill Roberts article's I see posted every so often?

http://mesomorphosis.com/articles/

 

[Dutch windmill]

^^

D.W.