why is tren toxic?

[Bozwell]

Ive always wonders about using tren so Ive reaserched and still cant find out why its so toxic and stressfull on the kidneys I know orals are toxic becuase of the 17a and thus stressfull on the liver but tren seem to be the only oil based injectable steriod thats harmull why is this?
K for good answers

 

[lanky]

the three double bonds that the molecule of tren contains renders it a very stable product(which is also why tren has a yellow crystaline appearance. has to do with absorbtion of light from the three double bonds and emmision. why do you think beta carotene is orange, lots or double bonds that make good resonance structures and absorb and emit light(i could go on forever about the light spectrum, valence shell, hunds rule) anyway ( the greater the stability, the harder it is for the body to make changes to the molecule so it can be excreted.(changes are usually done in one of three to four mechanisms. the 17-OH will become a keto, the 3-keto will become an OH, or some sort of trimethylsilyl, or glucuronic acid conjugation. Most steroids go through 3 or more of these steps, it just differs in the ratio of metabolites between the steroids.

 

[bigtasty25]

so if its harder to brake down by the body...its basically putting more stress on the body in simplistic terms? kidneys in this case im assuming. For those of us without pharmacology/chemistry degrees plz lol =)

 

[lanky]

Yea. i am not sure about its toxicity on the kidneys, it has been a few months since ive reviewed my anabolic library(stacks of journals, transcribed japaneese research unknown to most, other hard to find tidbits, organic reference databases etc. ). From what i have been reading on the anabolic board people are extracting this substance from the agricultural products, they are using solvents and if they make it themselves chances are it is not a pure product of what they inject into their bodies( not sterile and may/will contain impurituies) this sets the individual up for health problems, I cant remember off the top of my head if trenbolone by itself is toxic to the kidneys directly, indirectly maybe if there is fluid volume excess secondary to increased protien synthesis(excess anabolism and/or catabolism creates a shift in water production/electrolyte balance efect the renal system, cardiopulmonary system( someone who has CHF, COPD have an exacerbation when increased fluid volumes are present. they come to the ER give them lasix) Basicly summing up this. {Increases in fluid can cause problems for the body. Anabolics can cause fluid imbalances and hypertension which can cause renal problems. Non sterile product may cause bacteremia/ and Nephrotoxic conditions. I can go on all day about why not to inject yourself with anything that did not come from a real pharmacy.

 

[ass_face]

It isn't. That's a misnomer perpetuated by the early studies of Parabolan. The Hydrohexacarbonate ester was toxic. Trenbolone is not.

 

[lanky]

It isn't. That's a misnomer perpetuated by the early studies of Parabolan. The Hydrohexacarbonate ester was toxic. Trenbolone is not.

Are you saying this in regards to renal toxicity, or hepatic.

 

[ass_face]

Are you saying this in regards to renal toxicity, or hepatic.

Both... there is no toxicity. I have done about 8 tren cycles with blood work. My renal function did not change at all and my liver function stayed the same. No fluctuation at all. I would suggest always staying hydrated with tren, as it makes you sweat alot... but other than that all the mystical snake oil shit like Tyler's Liver detox etc, is completely unnecessary. The Acetate and Enanthate ester are safe to use... the ester used in Parabolan was the apparent cause of the toxicity.

 

[bigtasty25]

no parabolan for me then =)