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Why is deca so suppresive

It's not extremly supressive to ALL but to most. Nondrolone is a based on progesterone (estrogen) and it seems to do a nice job at shutting guys down hard and for a Loooooonnnnggggggg time.
 
GREGORY said:
It's not extremly supressive to ALL but to most. Nondrolone is a based on progesterone (estrogen) and it seems to do a nice job at shutting guys down hard and for a Loooooonnnnggggggg time.

I think the LONG TIME part is a function of the deca ester and its affinity for fat cells. so theorectically, then (if this is true) while NPP should be as efficient at shutting you down, the length of shutdown time (untreated) should be as short as anything else.

please chime in if I have this wrong.
 
Nandrolone seems not only to shut down the HPTA, it also destroys the ability of the testes to make testosterone at all. Read:

J Reprod Fertil. 1999 Mar;115(2):373-9. Related Articles,Links

Effects of anabolic steroid (19-nortestosterone) on the secretion of testicular hormones in the stallion.

Nagata S, Kurosawa M, Mima K, Nambo Y, Fujii Y, Watanabe G, Taya K.

Laboratory of Racing Chemistry, Tochigi, Japan.

The aim of this study was to clarify the effect of anabolic steroids on the testicular endocrine function of mature stallions. Mature thoroughbred stallions were treated with 800 mg nandrolone decanoate every 3 weeks for 3 months. After the first treatment, plasma concentrations of LH, immunoreactive inhibin and testosterone decreased rapidly to the nadir. These hormones were maintained at significantly lower concentrations compared with concentrations in intact stallions. Histology of the testicular tissue indicated the arrest of advanced spermatogenesis in the seminiferous tubules and a severe depletion of the number of Leydig cells in the interstitial compartment as a result of treatment.
[...]

(the leydig cells make testosterone in the testes) there is an older study who found that while ND decreases LH production it shuts down endogeneus testosterone even more. they did not do a histology on their human subjects obviously but it is certainly for the same reason: nandrolone kills testosterone producing cells in the testes. in most cases they come/grow back, but it takes longer that just to wait for LH to be restored and in some cases they never come back fully.
 
geoboy said:
I think the LONG TIME part is a function of the deca ester and its affinity for fat cells. so theorectically, then (if this is true) while NPP should be as efficient at shutting you down, the length of shutdown time (untreated) should be as short as anything else.

please chime in if I have this wrong.


It pretty much is as effective at shutting you down, but the cycle lenght is never as long in duration with NPP as it is with nondrolone. If the ester was the only culprit then even with test Sust would be much harder to recoover from then Prop, and come to think of it it may be but not with such a major difference. Deca is special in this regard. And the fat holds only it's metabolites, totally inert.
 
Triple-G said:
Nandrolone seems not only to shut down the HPTA, it also destroys the ability of the testes to make testosterone at all. Read:

J Reprod Fertil. 1999 Mar;115(2):373-9. Related Articles,Links

Effects of anabolic steroid (19-nortestosterone) on the secretion of testicular hormones in the stallion.

Nagata S, Kurosawa M, Mima K, Nambo Y, Fujii Y, Watanabe G, Taya K.

Laboratory of Racing Chemistry, Tochigi, Japan.

The aim of this study was to clarify the effect of anabolic steroids on the testicular endocrine function of mature stallions. Mature thoroughbred stallions were treated with 800 mg nandrolone decanoate every 3 weeks for 3 months. After the first treatment, plasma concentrations of LH, immunoreactive inhibin and testosterone decreased rapidly to the nadir. These hormones were maintained at significantly lower concentrations compared with concentrations in intact stallions. Histology of the testicular tissue indicated the arrest of advanced spermatogenesis in the seminiferous tubules and a severe depletion of the number of Leydig cells in the interstitial compartment as a result of treatment.
[...]

(the leydig cells make testosterone in the testes) there is an older study who found that while ND decreases LH production it shuts down endogeneus testosterone even more. they did not do a histology on their human subjects obviously but it is certainly for the same reason: nandrolone kills testosterone producing cells in the testes. in most cases they come/grow back, but it takes longer that just to wait for LH to be restored and in some cases they never come back fully.

Interesting read bro.
 
Triple-G said:
Nandrolone seems not only to shut down the HPTA, it also destroys the ability of the testes to make testosterone at all. Read:

J Reprod Fertil. 1999 Mar;115(2):373-9. Related Articles,Links

Effects of anabolic steroid (19-nortestosterone) on the secretion of testicular hormones in the stallion.

Nagata S, Kurosawa M, Mima K, Nambo Y, Fujii Y, Watanabe G, Taya K.

Laboratory of Racing Chemistry, Tochigi, Japan.

The aim of this study was to clarify the effect of anabolic steroids on the testicular endocrine function of mature stallions. Mature thoroughbred stallions were treated with 800 mg nandrolone decanoate every 3 weeks for 3 months. After the first treatment, plasma concentrations of LH, immunoreactive inhibin and testosterone decreased rapidly to the nadir. These hormones were maintained at significantly lower concentrations compared with concentrations in intact stallions. Histology of the testicular tissue indicated the arrest of advanced spermatogenesis in the seminiferous tubules and a severe depletion of the number of Leydig cells in the interstitial compartment as a result of treatment.
[...]

(the leydig cells make testosterone in the testes) there is an older study who found that while ND decreases LH production it shuts down endogeneus testosterone even more. they did not do a histology on their human subjects obviously but it is certainly for the same reason: nandrolone kills testosterone producing cells in the testes. in most cases they come/grow back, but it takes longer that just to wait for LH to be restored and in some cases they never come back fully.


That is absolutely right and also the reason why it takes so long to recover from. It's not just a matter of getting the LH restored, your testicles may literally be damaged.
 
Triple-G said:
Nandrolone seems not only to shut down the HPTA, it also destroys the ability of the testes to make testosterone at all. Read:

J Reprod Fertil. 1999 Mar;115(2):373-9. Related Articles,Links

Effects of anabolic steroid (19-nortestosterone) on the secretion of testicular hormones in the stallion.

Nagata S, Kurosawa M, Mima K, Nambo Y, Fujii Y, Watanabe G, Taya K.

Laboratory of Racing Chemistry, Tochigi, Japan.

The aim of this study was to clarify the effect of anabolic steroids on the testicular endocrine function of mature stallions. Mature thoroughbred stallions were treated with 800 mg nandrolone decanoate every 3 weeks for 3 months. After the first treatment, plasma concentrations of LH, immunoreactive inhibin and testosterone decreased rapidly to the nadir. These hormones were maintained at significantly lower concentrations compared with concentrations in intact stallions. Histology of the testicular tissue indicated the arrest of advanced spermatogenesis in the seminiferous tubules and a severe depletion of the number of Leydig cells in the interstitial compartment as a result of treatment.
[...]

(the leydig cells make testosterone in the testes) there is an older study who found that while ND decreases LH production it shuts down endogeneus testosterone even more. they did not do a histology on their human subjects obviously but it is certainly for the same reason: nandrolone kills testosterone producing cells in the testes. in most cases they come/grow back, but it takes longer that just to wait for LH to be restored and in some cases they never come back fully.
Thats harsh,it dosnt shut you down it kills you off :worried: no deca for me then!!
That clears up why so many people hate deca :evil:
 
Im not sure though I wouldnt be so fast as to count it out. Alot of people do not have problems with it. It does not effect me like that, I have increades libido and recover just fine from it. I have friends and others on the boards who love it. I think if it works for you it could be a very good thing. However I do think it may have a negative effect if you do use it for too many ccyles. But just switch it up every once and ahwil and that could help. I like deca....
 
Triple-G said:
Nandrolone seems not only to shut down the HPTA, it also destroys the ability of the testes to make testosterone at all. Read:

J Reprod Fertil. 1999 Mar;115(2):373-9. Related Articles,Links

Effects of anabolic steroid (19-nortestosterone) on the secretion of testicular hormones in the stallion.

Nagata S, Kurosawa M, Mima K, Nambo Y, Fujii Y, Watanabe G, Taya K.

Laboratory of Racing Chemistry, Tochigi, Japan.

The aim of this study was to clarify the effect of anabolic steroids on the testicular endocrine function of mature stallions. Mature thoroughbred stallions were treated with 800 mg nandrolone decanoate every 3 weeks for 3 months. After the first treatment, plasma concentrations of LH, immunoreactive inhibin and testosterone decreased rapidly to the nadir. These hormones were maintained at significantly lower concentrations compared with concentrations in intact stallions. Histology of the testicular tissue indicated the arrest of advanced spermatogenesis in the seminiferous tubules and a severe depletion of the number of Leydig cells in the interstitial compartment as a result of treatment.
[...]

(the leydig cells make testosterone in the testes) there is an older study who found that while ND decreases LH production it shuts down endogeneus testosterone even more. they did not do a histology on their human subjects obviously but it is certainly for the same reason: nandrolone kills testosterone producing cells in the testes. in most cases they come/grow back, but it takes longer that just to wait for LH to be restored and in some cases they never come back fully.

Got any reports on Tren? And K by the way.
 
Triple-G said:
Nandrolone seems not only to shut down the HPTA, it also destroys the ability of the testes to make testosterone at all. Read:

J Reprod Fertil. 1999 Mar;115(2):373-9. Related Articles,Links

Effects of anabolic steroid (19-nortestosterone) on the secretion of testicular hormones in the stallion.

Nagata S, Kurosawa M, Mima K, Nambo Y, Fujii Y, Watanabe G, Taya K.

Laboratory of Racing Chemistry, Tochigi, Japan.

The aim of this study was to clarify the effect of anabolic steroids on the testicular endocrine function of mature stallions. Mature thoroughbred stallions were treated with 800 mg nandrolone decanoate every 3 weeks for 3 months. After the first treatment, plasma concentrations of LH, immunoreactive inhibin and testosterone decreased rapidly to the nadir. These hormones were maintained at significantly lower concentrations compared with concentrations in intact stallions. Histology of the testicular tissue indicated the arrest of advanced spermatogenesis in the seminiferous tubules and a severe depletion of the number of Leydig cells in the interstitial compartment as a result of treatment.
[...]

(the leydig cells make testosterone in the testes) there is an older study who found that while ND decreases LH production it shuts down endogeneus testosterone even more. they did not do a histology on their human subjects obviously but it is certainly for the same reason: nandrolone kills testosterone producing cells in the testes. in most cases they come/grow back, but it takes longer that just to wait for LH to be restored and in some cases they never come back fully.
Post a link where you found this study, I hate deca, it took me 6months to recover to my natural levels.
 
I love deca bros. Never had deca dick (600mg or less a week) and alwasy recover fine. I guess I am just lucky though. Deca was the first AAS that I ever used and I ran it by itself and kept about 90 % of my gains with no pct.(i was an idiot and didnt know about pct then) But I have lots of bros that seem to have nearly impossible times recovering from deca.
 
yomama said:
Post a link where you found this study, I hate deca, it took me 6months to recover to my natural levels.

How much were you taking and for how long?

Did you use any pct, like clomid?

Were you stacking the deca with anything else?
 
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