GREGORY said:It's not extremly supressive to ALL but to most. Nondrolone is a based on progesterone (estrogen) and it seems to do a nice job at shutting guys down hard and for a Loooooonnnnggggggg time.
geoboy said:I think the LONG TIME part is a function of the deca ester and its affinity for fat cells. so theorectically, then (if this is true) while NPP should be as efficient at shutting you down, the length of shutdown time (untreated) should be as short as anything else.
please chime in if I have this wrong.
Triple-G said:Nandrolone seems not only to shut down the HPTA, it also destroys the ability of the testes to make testosterone at all. Read:
J Reprod Fertil. 1999 Mar;115(2):373-9. Related Articles,Links
Effects of anabolic steroid (19-nortestosterone) on the secretion of testicular hormones in the stallion.
Nagata S, Kurosawa M, Mima K, Nambo Y, Fujii Y, Watanabe G, Taya K.
Laboratory of Racing Chemistry, Tochigi, Japan.
The aim of this study was to clarify the effect of anabolic steroids on the testicular endocrine function of mature stallions. Mature thoroughbred stallions were treated with 800 mg nandrolone decanoate every 3 weeks for 3 months. After the first treatment, plasma concentrations of LH, immunoreactive inhibin and testosterone decreased rapidly to the nadir. These hormones were maintained at significantly lower concentrations compared with concentrations in intact stallions. Histology of the testicular tissue indicated the arrest of advanced spermatogenesis in the seminiferous tubules and a severe depletion of the number of Leydig cells in the interstitial compartment as a result of treatment.
[...]
(the leydig cells make testosterone in the testes) there is an older study who found that while ND decreases LH production it shuts down endogeneus testosterone even more. they did not do a histology on their human subjects obviously but it is certainly for the same reason: nandrolone kills testosterone producing cells in the testes. in most cases they come/grow back, but it takes longer that just to wait for LH to be restored and in some cases they never come back fully.
Triple-G said:Nandrolone seems not only to shut down the HPTA, it also destroys the ability of the testes to make testosterone at all. Read:
J Reprod Fertil. 1999 Mar;115(2):373-9. Related Articles,Links
Effects of anabolic steroid (19-nortestosterone) on the secretion of testicular hormones in the stallion.
Nagata S, Kurosawa M, Mima K, Nambo Y, Fujii Y, Watanabe G, Taya K.
Laboratory of Racing Chemistry, Tochigi, Japan.
The aim of this study was to clarify the effect of anabolic steroids on the testicular endocrine function of mature stallions. Mature thoroughbred stallions were treated with 800 mg nandrolone decanoate every 3 weeks for 3 months. After the first treatment, plasma concentrations of LH, immunoreactive inhibin and testosterone decreased rapidly to the nadir. These hormones were maintained at significantly lower concentrations compared with concentrations in intact stallions. Histology of the testicular tissue indicated the arrest of advanced spermatogenesis in the seminiferous tubules and a severe depletion of the number of Leydig cells in the interstitial compartment as a result of treatment.
[...]
(the leydig cells make testosterone in the testes) there is an older study who found that while ND decreases LH production it shuts down endogeneus testosterone even more. they did not do a histology on their human subjects obviously but it is certainly for the same reason: nandrolone kills testosterone producing cells in the testes. in most cases they come/grow back, but it takes longer that just to wait for LH to be restored and in some cases they never come back fully.
Thats harsh,it dosnt shut you down it kills you offTriple-G said:Nandrolone seems not only to shut down the HPTA, it also destroys the ability of the testes to make testosterone at all. Read:
J Reprod Fertil. 1999 Mar;115(2):373-9. Related Articles,Links
Effects of anabolic steroid (19-nortestosterone) on the secretion of testicular hormones in the stallion.
Nagata S, Kurosawa M, Mima K, Nambo Y, Fujii Y, Watanabe G, Taya K.
Laboratory of Racing Chemistry, Tochigi, Japan.
The aim of this study was to clarify the effect of anabolic steroids on the testicular endocrine function of mature stallions. Mature thoroughbred stallions were treated with 800 mg nandrolone decanoate every 3 weeks for 3 months. After the first treatment, plasma concentrations of LH, immunoreactive inhibin and testosterone decreased rapidly to the nadir. These hormones were maintained at significantly lower concentrations compared with concentrations in intact stallions. Histology of the testicular tissue indicated the arrest of advanced spermatogenesis in the seminiferous tubules and a severe depletion of the number of Leydig cells in the interstitial compartment as a result of treatment.
[...]
(the leydig cells make testosterone in the testes) there is an older study who found that while ND decreases LH production it shuts down endogeneus testosterone even more. they did not do a histology on their human subjects obviously but it is certainly for the same reason: nandrolone kills testosterone producing cells in the testes. in most cases they come/grow back, but it takes longer that just to wait for LH to be restored and in some cases they never come back fully.
no deca for me then!!
Triple-G said:Nandrolone seems not only to shut down the HPTA, it also destroys the ability of the testes to make testosterone at all. Read:
J Reprod Fertil. 1999 Mar;115(2):373-9. Related Articles,Links
Effects of anabolic steroid (19-nortestosterone) on the secretion of testicular hormones in the stallion.
Nagata S, Kurosawa M, Mima K, Nambo Y, Fujii Y, Watanabe G, Taya K.
Laboratory of Racing Chemistry, Tochigi, Japan.
The aim of this study was to clarify the effect of anabolic steroids on the testicular endocrine function of mature stallions. Mature thoroughbred stallions were treated with 800 mg nandrolone decanoate every 3 weeks for 3 months. After the first treatment, plasma concentrations of LH, immunoreactive inhibin and testosterone decreased rapidly to the nadir. These hormones were maintained at significantly lower concentrations compared with concentrations in intact stallions. Histology of the testicular tissue indicated the arrest of advanced spermatogenesis in the seminiferous tubules and a severe depletion of the number of Leydig cells in the interstitial compartment as a result of treatment.
[...]
(the leydig cells make testosterone in the testes) there is an older study who found that while ND decreases LH production it shuts down endogeneus testosterone even more. they did not do a histology on their human subjects obviously but it is certainly for the same reason: nandrolone kills testosterone producing cells in the testes. in most cases they come/grow back, but it takes longer that just to wait for LH to be restored and in some cases they never come back fully.
Post a link where you found this study, I hate deca, it took me 6months to recover to my natural levels.Triple-G said:Nandrolone seems not only to shut down the HPTA, it also destroys the ability of the testes to make testosterone at all. Read:
J Reprod Fertil. 1999 Mar;115(2):373-9. Related Articles,Links
Effects of anabolic steroid (19-nortestosterone) on the secretion of testicular hormones in the stallion.
Nagata S, Kurosawa M, Mima K, Nambo Y, Fujii Y, Watanabe G, Taya K.
Laboratory of Racing Chemistry, Tochigi, Japan.
The aim of this study was to clarify the effect of anabolic steroids on the testicular endocrine function of mature stallions. Mature thoroughbred stallions were treated with 800 mg nandrolone decanoate every 3 weeks for 3 months. After the first treatment, plasma concentrations of LH, immunoreactive inhibin and testosterone decreased rapidly to the nadir. These hormones were maintained at significantly lower concentrations compared with concentrations in intact stallions. Histology of the testicular tissue indicated the arrest of advanced spermatogenesis in the seminiferous tubules and a severe depletion of the number of Leydig cells in the interstitial compartment as a result of treatment.
[...]
(the leydig cells make testosterone in the testes) there is an older study who found that while ND decreases LH production it shuts down endogeneus testosterone even more. they did not do a histology on their human subjects obviously but it is certainly for the same reason: nandrolone kills testosterone producing cells in the testes. in most cases they come/grow back, but it takes longer that just to wait for LH to be restored and in some cases they never come back fully.
yomama said:Post a link where you found this study, I hate deca, it took me 6months to recover to my natural levels.
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