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why is aromasin superoir?

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steroid_myth_buster

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just wanted to see why aromaisn wich is expensive considered the " cream of the crop"..




steroid_myth_buster!
 
Its supposed to not f*** up your lipid profile nearly as bad as the other AI's. Its also supposed to downregulate progestone receptors, though how well I don't know yet, I'm still on formestanes boat for that one, but then again I haven't tried aromasin yet cause I still have lots of formestane ;)
 
steroid_myth_buster said:
just wanted to see why aromaisn wich is expensive considered the " cream of the crop"..




steroid_myth_buster!


Its better because it does not reduce estrogen, it deactivates it. Estrogen is necessary in your liver but bad when excess amounts bind to receptor sites. Aromasin (Extremestane) inhibits estrogen's ability to bind.
 
ill let u know when i run it, but iam prone to bloat even if i look at a bottle of test, so i finally invested in masin i hope it works but i can only afford to run 20mg a day and now im hearin that is a lower dose, w'ell see
 
I've posted this before, it's a good read:

--------------------------------------------------------------------------------

Here's a good read:


Aromasin will not effect your lipids. Here is a good article I got some time back, don't ask me where I can't remeber for sure. But, it is a good read:

The Best Anti-E

theres been a lot of talk on other boards about this lately, and a lot of bad information thrown out as well. i wanted to share the good info.

somone keeps posting how letrozole is the strongest and doesnt negatively affect cholesterol. this is not true. letrozole is NOT the strongest and it DOES negative affect cholesterol/lipid profile in a bad way.

aromasin(exemestane) is the best. this is why

both arimidex/ldex/anastrozole and femara/letrozole hurt your cholesterol. the way these 2 anti e's work is they inhibit the aromatase enzyme. by inhibiting the enzyme which converts testosterone to estrogen, you reduce or even come close to eliminating estrogen production. we need some estrogen to be healthy. the major drawback to this is without estrogen, your lipid profile gets fucked.

exemestane works differently. it does not stop the body from producing estrogen. rather, it makes it so the estrogen is unable to bind to receptors by deactivating the binding enzyme. if the estrogen cannot bind, you simply will not get bloated or get gyno. the estrogen is crippled due to exemestane. however, since the estrogen is still floating around, it will not negatively affect your lipid/cholesterol profile.

anastrozole doesnt cause a rebound effect, and neither does exemestane, but letrozole does. this means after you stop the letrozole, your estrogen rebounds and goes pretty high for a while, eventually it normalizes. you can avoid this by tapering your letro dose down before stopping it, but that is a pain in the ass. higher than normal can mess many things up post cycle when you stop. since the hpta has a feedback loop is primarily controlled by estrogen, high estrogen will tell your hpta to produce less testosterone, because it thinks the high estrogen is caused by too much testosterone. this is fact. now post cycle, dont we want to raise our test levels, not lower them? of course! so rebounds are bad. if you use letro taper the dose off to zero over a couple weeks.

fyi- nolvadex(tamoxifen) is a SERM(Selective Estrogen Receptor Modulator). this means on certain tissue it can act antagonisticaly or agonistically. in the case of lipid profiles, it acts agonistically. so, running tamoxifen with your anti e's will IMPROVE your cholesterol profile even if not on cycle or using any gear or other anti e's. its just plain good for cholesterol.

one thing to keep in mind though when runing tamoxifen with letro. letro reduces blood levels of tamoxifen by over 50%. a study showed 2.5mg letro ed made nolva levels drop to 40% of what they were before adding letro. this does not mean you cant use tamoxifen with letro, it just means you need to use more, about double. 20mg of nolva will act like 8mg if running letro. so make sure you are aware of this because you will need to buy more nolva to compensate. this does not happen when mixing tamoxifen with anastrozole or exemestane, it only hppens with letro.

also, many people and myself experince a reduction of libido on letro. this doesnt happen w/ ldex or exmestane as far as i know, and in my own experience, and ive run all 3 quite a bit.

the best combo IS exemestane and tamoxifen together. your cholesterol will be as good as can be considering your on a cycle of steroids. the dose of aromasin will vary depending on the users needs and how much aromatizing gear is being taken. usually 10-25mg ed works well. run 10mg ed nolva to improve your cholesterol.

second best combo i feel is anastrozole(ldex) and tamoxifen. ldex dose ranges from usually .15mg ed to 1mg ed. run 10mg nolva ed to improve cholesterol.

thierd best is letro and nolvadex. letro doses usually range from 1-2.5mg ed. run 20mg ed nolva to improve cholesterol w/ letro.

you do not need to run nolva with any of these 3, i do recomend it though as it will improve cholesterol compared to using the anti e's alone without nolva.

so in order of strength, on a dose per dose basis(not mg per mg) aromasin is def the strognest, next is letro, and then ldex.
 
Throw2Far said:
Its better because it does not reduce estrogen, it deactivates it. Estrogen is necessary in your liver but bad when excess amounts bind to receptor sites. Aromasin (Extremestane) inhibits estrogen's ability to bind.
No. Aromasin kills off the enzymes that convert test to estrogen. So there is less E produced. Nolva blocks binding. Arimidex only inhibits the aromatese enzymes. So aromasin is more effective.
 
good reads and stuff, i just placed an order for some. how long does it take to feel aromasins effects?
 
Ulter said:
No. Aromasin kills off the enzymes that convert test to estrogen. So there is less E produced. Nolva blocks binding. Arimidex only inhibits the aromatese enzymes. So aromasin is more effective.


Then what accounts for the better lipids when using aromasin as opposed to arimidex?
 
Ulter said:
That's the rumor. Unforturnately there are two studies and each came to opposite conclusions.


well thats what im all about, clearing up rumor's and of course learning
 
Realy..so even testosterone trashes your lipid profile. I was always under the impression that...since one doesent use AI's and take the bloat and estrogen associated with aas, the estrogen will control the cholesterol.
 
Nope, sorry. AS will do it all by itself.

Fundam Clin Pharmacol. 2005 Feb;19(1):27-44.

Pharmacoepidemiology of anabolic androgenic steroids: a review.

Thiblin I, Petersson A.

Department of Forensic Medicine, Uppsala University, S-752 37, Uppsala, Sweden. [email protected]

Non-prescribed use of anabolic androgenic steroids (AAS) has been associated with a number of physical and psychiatric/behavioural complications, some of which are potentially lethal. Here, we review both observational and experimental studies on human subjects concerned with such side-effects. The only physical complication of AAS use that receives definitive support from such investigations is unfavourable changes in blood lipid profiles. Support for various psychiatric complications has also been provided by a number of cross-sectional studies, most involving comparisons between weight-training individuals who use or do not use AAS.
 
how do we fix this lipid trashing? lots of water? nolva? thats one reason i wanna get on aromasin and get off letro
 
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