I just started lifting again after about 6 months off. When would be a good time to start a cycle, never have done one, but I know what I am going to do.
I am currently 6'4" 260 pounds, 36" waist, so naturally pretty big
Well, I'd wait to see how much you can grow naturally in the next 6-12 months. Allow your muscles to achieve"muscle memory" at the very least. After that just listen to your body and it will let you know.