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Whats the differnece between total test and free test?

xonic2xonic2

New member
I know that free test means bio-availabe but I don't really understand the differneces and specifically why someone would claim that clomid increases test but not free test....
 
http://www.labcorp.com/datasets/labcorp/html/chapter/mono/sr003800.htm

The concentration of free testosterone is very low, typically <2% of the total testosterone concentration. In most men and women, >50% of total circulating testosterone is bound to sex hormone-binding globulin (SHBG) and most of the rest is bound to albumin.2 Routinely available assay methods used to measure total testosterone are not sensitive enough to accurately quantitate the free testosterone fraction directly. Free testosterone is estimated in this panel by an indirect method, equilibrium ultrafiltration. Tritiated testosterone is added to the sample and allowed to come to equilibrium with testosterone in the serum at physiological temperature.3,4 The amount of the added radiolabled testosterone must be low enough to ensure that the addition will not significantly increase the total testosterone concentration. Once equilibrium is achieved, the free testosterone is separated from the bound by filtration through a membrane by centrifugal ultrafiltration.5 The radioactivity of the protein-free ultrafiltrate is measured and used to calculate the percent free testosterone. The concentration of free testosterone is then calculated by multiplying the percent free testosterone by the total testosterone concentration.
 
Seems to me the holy grail is to find the way to make more free test available. I know Avena Sativa are recommended, and Nettle leaf.
How long their effects last for though are questionable. We need an SHBG blocker!
 
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