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what makes halotestin more toxic....
- Thread starter djregs
- Start date
The Iron Game
New member
Athlete, it is bro
Italianboy
New member
Anavar is 17aa.
Check this out(hcemical structure for ANAVAR):
you can see the OH-CH3 group in 17 alpha position.All the 17AA(logical)have it.
Check this out(hcemical structure for ANAVAR):
you can see the OH-CH3 group in 17 alpha position.All the 17AA(logical)have it.
Italianboy
New member
Primobolan acetate isn't a 17aa.
17aa are:
Methiltest,Halotestin,Calusterone,Etinilesrenol(maxibolin),Dianabol,Anavar,Winstrol,Anadrol.
17aa are:
Methiltest,Halotestin,Calusterone,Etinilesrenol(maxibolin),Dianabol,Anavar,Winstrol,Anadrol.
Stangman99
New member
this was originally posted by weam a while backand if you used the search feature, you could've found it
The reason for why Halotestin is the harshest on the liver because Halo incorporates a combination of features including a 17-a methyl group, a 9-a fluorine, and a 11-OH group. Andronergic activity is increased 10 times and anabolic activity increased 20 times over that of 17-a methyl testosterone as with Anadrol
The chemical name for fluoxymesterone is androst-4-en-3-one, 9-fluoro11,17-dihydroxy-1,7-methyl-,(11b,7b)-.
you can easily find that it has 17A methyl(17alpha alkylated) which is absolutely toxic as with all other 17aa
but it contains 9alpha fluorine (as Fluorine is used to protect substances from breaking down as with Sodium fluoride and so on) this version of Fluorine is very toxic
and lastly Halotestin is very potent in the 11-Hydroxyl Group which is must be enzymatically reduced to the corresponding 11-hydroxy derivative before they are biologically active. This reaction is carried out by a distinct 11-hydroxysteroid dehydrogenase isozyme in the liver that operates in a reductive mode
this process by it self is an very toxic not just to the liver but for the renal function as well
all this major 3things makes it very toxic over all other drugs, look at something like Dianabol which is toxic it just toxic for 1 reason which is it's a 17alpha alkylated not like Halotestin
also Anadrol-50 is more toxic than Dianabol for one reason, a study used Anadrol found decreased glutathione production in hepatocytes that stanozolol did not cause (Welder AA, et al., J Pharmacol Toxicol Methods 33(4)187-95 1995 Aug)
and Stanazolol is same as Oxandrolone and Dianabol in toxication effects
Glutathione is a natural substance produced by the liver to protect it against toxic substances
N.B: the reason for why they called Halotestin by this name because it contains the halogen of Fluorine they reduced the gen word and replaced it with testin as a shortcut to Testosterone
The reason for why Halotestin is the harshest on the liver because Halo incorporates a combination of features including a 17-a methyl group, a 9-a fluorine, and a 11-OH group. Andronergic activity is increased 10 times and anabolic activity increased 20 times over that of 17-a methyl testosterone as with Anadrol
The chemical name for fluoxymesterone is androst-4-en-3-one, 9-fluoro11,17-dihydroxy-1,7-methyl-,(11b,7b)-.
you can easily find that it has 17A methyl(17alpha alkylated) which is absolutely toxic as with all other 17aa
but it contains 9alpha fluorine (as Fluorine is used to protect substances from breaking down as with Sodium fluoride and so on) this version of Fluorine is very toxic
and lastly Halotestin is very potent in the 11-Hydroxyl Group which is must be enzymatically reduced to the corresponding 11-hydroxy derivative before they are biologically active. This reaction is carried out by a distinct 11-hydroxysteroid dehydrogenase isozyme in the liver that operates in a reductive mode
this process by it self is an very toxic not just to the liver but for the renal function as well
all this major 3things makes it very toxic over all other drugs, look at something like Dianabol which is toxic it just toxic for 1 reason which is it's a 17alpha alkylated not like Halotestin
also Anadrol-50 is more toxic than Dianabol for one reason, a study used Anadrol found decreased glutathione production in hepatocytes that stanozolol did not cause (Welder AA, et al., J Pharmacol Toxicol Methods 33(4)187-95 1995 Aug)
and Stanazolol is same as Oxandrolone and Dianabol in toxication effects
Glutathione is a natural substance produced by the liver to protect it against toxic substances
N.B: the reason for why they called Halotestin by this name because it contains the halogen of Fluorine they reduced the gen word and replaced it with testin as a shortcut to Testosterone
Ummm...there's a great website you can visit to see a profile of anavar. I can't remember what it is....Oh wait it's my website. 
