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toremifene??
- Thread starter herdus33
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Mavafanculo
New member
the better tested "exotic" SERM is raloxifene as far as I know.
do you have any links for torm effectiveness at reversing existing gyno?
do you have any links for torm effectiveness at reversing existing gyno?
herdus33
New member
Mavafanculo said:
I do not have anything about treatment for existing gyno, but since toremifene is possibly stronger than nolvadex I was wondering if anyone has tried to use it for that reason?
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Here is a post from isteriods.com. I've highlights some of the more interesting points of why some of us that use AAS would consider using this substance.
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Fareston
Chemical Name: Toremifene Citrate
Drug Class: Selective Estrogen Receptor Modulator
Fareston is a Selective Estrogen Receptor Modulator (SERM), not unlike its more popular cousins Nolvadex and Clomid. Just as we see with Nolvadex, Fareston is used to treat breast cancer in post-menopausal women. It does this by exerting estrogen antagonistic effects in certain tissue, most notably, breast tissue. This is actually the same mechanism of action found in Nolvadex. This is why Nolvadex is often recommended to bodybuilders who are trying to avoid gynocomastia (growth of breast tissue in males). SERMs, in addition, have several other well known effects in men, which are not simply limited to preventing the abnormal growth of breast tissue.
At the hypothalamus and pituitary, estrogen acts in cooperation with the male body’s negative feedback loop to send a signal to decrease the secretion of LH, and when LH secretion is lowered, so are natural testosterone levels. SERMs, like Fareston, possibly act as an estrogen antagonist in the hypothalamus and pituitary, in order to increase testosterone production. Thus, although it hasn’t been studied to any great degree, it’s highly likely that Fareston is capable of increasing testosterone in the same way that Nolvadex it, as it’s androgenicity:estrogenicity ratio is 5x that of Nolvadex(1). It may also be better than Nolvadex for reasons that are of particular interest to steroid using athletes and bodybuilders.
Fareston differs from Nolvadex in several ways, however- even though it’s very similar to it in others. Firstly, the risk of certain side effects (although relatively rare with Nolvadex) is actually quite a bit lower with Fareston.However unlikely these risks are in the first place, the risk of stroke, pulmonary embolism, and cataract is probably lower with Fareston than with Nolvadex. This is going to be of interest to people who have issues with “floaters” in their vision, which is sometimes caused by Nolvadex and Clomid, as this product may represent significantly less occular toxicity. It also differs slightly from Nolvadex in its potent with regards to improving lipid (cholesterol) profiles. In terms of improving bone mineral density, Fareston is roughly equal to Nolvadex.(2)
Although anecdotal evidence on this compound is rare, bodybuilders who have already experimented with this stuff seem satisfied. In my estimation, it would seem to be a more potent and safer alternative to Nolvadex, for those who are worried about side effects. I’m also predicting that it may provide a greater increase in LH and therefore testosterone levels, in men when compared to Nolvadex (when an appropriate dose of each is utilized). This makes its use a strong possibility for PCT in the future, when studies on its ability to elevate testosterone is more fully studied and understood.
Fareston would also make a welcome addition to a cycle where Cholesterol issues may be a concern, or where something slightly stronger than Nolvadex may be required to prevent gyno.
References:
1. Breast Cancer Re Treat. 1990 Aug;16 Suppl:S3-7. Introduction to toremifene. Kangas L.
2. Breast 2006 Apr;15(2):142-57. Epub 2005 Nov 9.Toremifene: An evaluation of its safety profile. Harvey HA, Kimura , MHajba A
Mavafanculo
New member
good read -- this is one of those "try it and see" things.
herdus33
New member
Mavafanculo said:
Thanks Mava....I just thought the benefits concerning cholestrol would be a good thing for us. I guess I might have to just give it a go and share my results. The only problem I have is my source would be a research company. I woulnt like to give review based on research supps.
However, I was looking into raloxifene(sp?). Do you have any feedback about reversing pre-existing gyno? Either personal experience or that you have guided others experiences?? I know you are the one to somewhat bring this substance to topic.
Mavafanculo
New member
herdus33 said:
no, no personal feedback, but the studys indicate it's more effective than nolva at reversing existing gyno lumps.
as you probably know, only the serms nolva and raloxifene have studys showing reversal. arimidex was included in one of the studys and was ineffective.
my feeling is that based on bro-ology (positive anecdotal buzz in the BB community across many sites) when and if they study letro (and possibly aromasin) they will be found to reverse existing gyno - they may succeed where arimidex failed because they can virtually eliminate circulating estrogen where arimidex cannot.
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