test as a metabolic modifier

[the_only_sepe]

I allways hear test is the best metabolic modifier, then you have the people that say, no, anabolic steroids only preserve muscle, they dont help burn fat, I hear the same about anavar. which is right? I think they do help burn fat.

 

[the_only_sepe]

bump

 

[nautica]

I do not know if they burn fat per say, but probably just make the body more efficient with the nutrients it takes in.

Nautica

 

[HUCKLEBERRY FINNaplex]

Androgens in general will facillitate lipid mobilization,but one must concurrently pay attention to the production of estrogen in those anabolics that bind aromitase,as it can have the opposite effect,not only with sub-q fluid retention,but female-fat-pattern distribution.Test + liquidex=awesome hardening combo,creating the IDEAL environment,one rich in androgens and starved of estrogens...The study below will give you some data on the answers you are seeking.Enjoy my friend.

Testosterone deficiency in young men: marked alterations in whole body protein kinetics, strength, and adiposity.
Mauras N, Hayes V, Welch S, Rini A, Helgeson K, Dokler M, Veldhuis JD, Urban RJ
J Clin Endocrinol Metab 1998 Jun 83:1886-92

Abstract
To investigate specific effects of androgens on whole body metabolism, we studied six healthy lean men (mean +/- SEM age, 23.2 +/- 0.5 yr) before and after gonadal steroid suppression with a GnRH analog (Lupron), given twice, 3 weeks apart. Primed infusions of [13C]leucine, indirect calorimetry, isokinetic dynamometry, growth factor measurements, and percutaneous muscle biopsies were performed at baseline (D1) and after 10 weeks of treatment (D2); each subject served as his own control. Testosterone concentrations were markedly suppressed after 10 weeks of treatment (D1, 535 +/- 141 ng/dL; D2, 31 +/- 9). Leucine's rate of appearance (index of proteolysis) was markedly suppressed after 10 weeks of hypogonadism (-13%; P = 0.01) as well as the nonoxidative leucine disposal, an index of whole body protein synthesis (-13%; P = 0.01) without any changes in plasma amino acid concentrations. All subjects studied after 10 weeks showed a decrease in fat-free mass, as measured by skinfold calipers and dual emission x-ray absortiometry scans (D1, 56.5 +/- 2.9 kg; D2, 54.4 +/- 2.5; P = 0.005), and an increase in percent fat mass (D1, 19.2 +/- 2.5%; D2, 22.2 +/- 2.5; P = 0.001). Rates of lipid oxidation decreased (-31%; P = 0.05) after treatment, with parallel changes in resting energy expenditure (-9%; P = 0.05). Mean and peak GH concentrations (measured every 10 min for 6 h) and GH production rates did not decrease after testosterone deficiency, with an actual increase in basal secretion (P < 0.02). Plasma insulin-like growth factor I (IGF-I) concentrations did not change significantly after 10 weeks of treatment (D1, 227 +/- 44 micrograms/L; D2, 291 +/- 60; P = 0.08). Isokinetic dynamometry of leg extensors at 60 degrees and 180 degrees/s was also decreased after 10 weeks of hypogonadism. Total ribonucleic acid (RNA) was isolated from muscle biopsy samples, and ribonuclease protection assays were performed using human complementary DNA clones for IGF-I, IGF-binding protein-4, myosin, and actin. Ten weeks after Lupron treatment, messenger RNA (mRNA) concentrations of IGF-I decreased significantly, whereas there was a trend toward higher IGF-binding protein-4 concentrations, with no change in myosin or actin mRNA concentrations. In conclusion, testosterone deficiency in young men is associated with a marked decrease in measures of whole body protein anabolism, decreased strength, decreased fat oxidation, and increased adiposity. These effects of testosterone deficiency are independent of changes in peripheral GH production and IGF-I concentrations, even though im IGF-I mRNA concentrations decrease. These data suggest a direct effect of androgens on whole body lipid and protein metabolism.

 

[pauly]

Androgens in general will facillitate lipid mobilization,but one must concurrently pay attention to the production of estrogen in those anabolics that bind aromitase,as it can have the opposite effect,not only with sub-q fluid retention,but female-fat-pattern distribution.Test + liquidex=awesome hardening combo,creating the IDEAL environment,one rich in androgens and starved of estrogens...The study below will give you some data on the answers you are seeking.Enjoy my friend.

Testosterone deficiency in young men: marked alterations in whole body protein kinetics, strength, and adiposity.
Mauras N, Hayes V, Welch S, Rini A, Helgeson K, Dokler M, Veldhuis JD, Urban RJ
J Clin Endocrinol Metab 1998 Jun 83:1886-92

Abstract
To investigate specific effects of androgens on whole body metabolism, we studied six healthy lean men (mean +/- SEM age, 23.2 +/- 0.5 yr) before and after gonadal steroid suppression with a GnRH analog (Lupron), given twice, 3 weeks apart. Primed infusions of [13C]leucine, indirect calorimetry, isokinetic dynamometry, growth factor measurements, and percutaneous muscle biopsies were performed at baseline (D1) and after 10 weeks of treatment (D2); each subject served as his own control. Testosterone concentrations were markedly suppressed after 10 weeks of treatment (D1, 535 +/- 141 ng/dL; D2, 31 +/- 9). Leucine's rate of appearance (index of proteolysis) was markedly suppressed after 10 weeks of hypogonadism (-13%; P = 0.01) as well as the nonoxidative leucine disposal, an index of whole body protein synthesis (-13%; P = 0.01) without any changes in plasma amino acid concentrations. All subjects studied after 10 weeks showed a decrease in fat-free mass, as measured by skinfold calipers and dual emission x-ray absortiometry scans (D1, 56.5 +/- 2.9 kg; D2, 54.4 +/- 2.5; P = 0.005), and an increase in percent fat mass (D1, 19.2 +/- 2.5%; D2, 22.2 +/- 2.5; P = 0.001). Rates of lipid oxidation decreased (-31%; P = 0.05) after treatment, with parallel changes in resting energy expenditure (-9%; P = 0.05). Mean and peak GH concentrations (measured every 10 min for 6 h) and GH production rates did not decrease after testosterone deficiency, with an actual increase in basal secretion (P < 0.02). Plasma insulin-like growth factor I (IGF-I) concentrations did not change significantly after 10 weeks of treatment (D1, 227 +/- 44 micrograms/L; D2, 291 +/- 60; P = 0.08). Isokinetic dynamometry of leg extensors at 60 degrees and 180 degrees/s was also decreased after 10 weeks of hypogonadism. Total ribonucleic acid (RNA) was isolated from muscle biopsy samples, and ribonuclease protection assays were performed using human complementary DNA clones for IGF-I, IGF-binding protein-4, myosin, and actin. Ten weeks after Lupron treatment, messenger RNA (mRNA) concentrations of IGF-I decreased significantly, whereas there was a trend toward higher IGF-binding protein-4 concentrations, with no change in myosin or actin mRNA concentrations. In conclusion, testosterone deficiency in young men is associated with a marked decrease in measures of whole body protein anabolism, decreased strength, decreased fat oxidation, and increased adiposity. These effects of testosterone deficiency are independent of changes in peripheral GH production and IGF-I concentrations, even though im IGF-I mRNA concentrations decrease. These data suggest a direct effect of androgens on whole body lipid and protein metabolism.

...i think i just came.

 

[solidspine]

I did a test only cycle not to long ago and ate a lot, but clean which is not my strength, anyway I gained weight and lost bf, while eating like a horse and only doing cardio 3 times a week.

I always seem to lose bf on any cycle, it could be the test, I have never done a "cutting" cycle with the exception of 3 months on and off clen finished by 14 days on dnp.

 

[HUCKLEBERRY FINNaplex]

Up for Mr. Sepe...

 

[Super Halo Man]

I would say so... I hear a lot of people preach Test/Winny. Give it a whirl and see. Done right, I do not think you will be disappointed.

 

[serge]

running test/tren/nolvas right now, like what i see. the day after i added nolvas in i got 10 times harder, i love the shit

 

[BigDog60]

do you think femara would be just as good if not better for a test/tren/winny combo? I have some nolva but I was just going to keep that on hand for emergency nip itchin if it came to it Just making sure that nolva is much weaker than femara.

 

[the_only_sepe]

thanks for the good read huck