tagamet any conclusions?

[Enock]

Ok searching through the old threads I see contradictory information regarding tagamet (citidine or whatever) and its effect on the beta 2 receptors.

I've seen it compared as a replacement for Ketofen not quite as good but it does the job. I've also seen good points brought up about how the 2 meds are not anything alike and how are they both effecting the beta2s in such a positive mannor.

I've also seen the negative rumors of it decreasing test (I swear thats a rumor for every sup out there)

Heard about ketofen being better than caffine I assume it doesn't apply to tagamet?

So any gurus w/ information regarding tagamets actual effects both positive and negative?


Anyone with experience now?

I have a generic brand of tagamet and I've taken it, however obviously the effect of upregulating the b2s again isn't going to be instant and I'm pretty sure it didn't have any kind of synergistic effect w/ the ephedra + caffine. Its only day 1



FINAL VERDICT?

 

[Enock]

shit found this

http://nbaf.com/nbaf/aug7pgg.html

 

[cockdezl]

I can find no information showing cimetidine, or any of the common OTC H2 antagonists, has the ability to upregulate the adrenergic system, like ketotifen does.

Ketotifen is an H1 antagonist, much like diphenhydramine (Benadryl), but is seemingly unique in it's capacity for upregulation of the adrenergic system and reduction of Tumor Necrosis Factor. A similar drug, pizotifen, which is available in the US, may have this effect, but I have not found anything concerning this.

If it were simply an action of H1 antagonism, then we would have a nice arsenal of drugs to combat beta downregulation. We could go to the local pharmacy and choose from diphenhydramine, chlorpheniramine, brompheniramine, meclizine, etc.

If someone has anymore information concerning this topic, I would be interested. The histaminergic system has been relatively ignored.