You dont want to run it without anabolics. It will eat up muscle tissue. I am using it right now at top dose 100mcg. You start off at 25mcg then increase every 4 days to a max dose of 100mcg for 2 months total then scale down slowly to 25mcg.You will lose a good amount of bodyfat,if your diet statys clean.You will feel it in the second week, you will always be hot. Thats your body acting like a furnace.