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Strongest AI?
- Thread starter krishna
- Start date
tempest2003
New member
i would say dost. femera.
JumpBallWinner
New member
I think femera claims 5-30 times stronger than arimidex. I don't know if there is anything stronger,but I have a hard time believing anyone could need anything stronger than that. Regardless, bump for more those with more knowledge.
macrophage69alpha
New member
Femara is the strongest, at the clinical dosage of 2.5mg it can cause up to 99+% suppression.
it takes about 10-20mg of anastozole to acheive near that.
There is evidence that Femara suppresses secondary and tertiary conversion modes.
just so that everyone is aware aromatase is not the only pathway by which oestrogens are "made", they are by far the most prevalent, particularly when it comes to estradiol synthesis.
For most test based cycles reccomend Aromasin and AIFM, unless you have really bad oestrogen issues then femara is usually indicated. Dont really reccomend arimidex, unless you are one of those people that can cycle without issues anyways (ie you dont really need it that much), unless you plan to use higher than 1mg doses/ed (3-5mg).
note- with competitive inhibitors like letro and dex there is very good potential for rebound, so you may want to taper them with a suicidal AI like aromasin or AIFM.
it takes about 10-20mg of anastozole to acheive near that.
There is evidence that Femara suppresses secondary and tertiary conversion modes.
just so that everyone is aware aromatase is not the only pathway by which oestrogens are "made", they are by far the most prevalent, particularly when it comes to estradiol synthesis.
For most test based cycles reccomend Aromasin and AIFM, unless you have really bad oestrogen issues then femara is usually indicated. Dont really reccomend arimidex, unless you are one of those people that can cycle without issues anyways (ie you dont really need it that much), unless you plan to use higher than 1mg doses/ed (3-5mg).
note- with competitive inhibitors like letro and dex there is very good potential for rebound, so you may want to taper them with a suicidal AI like aromasin or AIFM.
M
Mr.X
Guest
krishna said:
Femara (letrozole).
Common doses depend on your cycles/goals. I usually suggest letrozole with nolvadex for gyno treatment. For most cycles all you need is arimidex.
tempest2003
New member
im very gyno prone, and right now am taking 2.5mg femera, and 20mg nolva e/d to nock out the symptoms i ran into. then plan on decreasing dosage to around 1.25 mg femera e/d and 10mg nolva e/d. do you think that is sufficent for someone very suceptable to gyno? or should i add some Aromasin too?
The strongest isn't the best. The strongest is TOO strong for most men and will kill your libido as well as cause other unwanted side effects. Many men would never use an anti-e years ago because they feared the negative effects of having estrogen levels that were too low. This was a misguided fear because the anti-e's didn't have the power to do that back then. Arimidex was too weak and nolva left plenty of E because it's really a SERM. Then Femara (letro) came along and those early fears became a reality. Men were getting E levels so low they couldn't get hard and they would get "too dry". Luckily Aromasin was made available and now there is something potent yet not so potent it's inhibiting. Aromasin and AIFM are the two "Best" AI's.
M
Mr.X
Guest
krishna said:
Read the feedback on letrozole + nolvadex, people on EF alone have gotten rid of gyno with the combination. I would say start him off with 1.25mgs of letrozole + 40mgs nolvadex ED.
I've already stated that I think his side effects using letro will be more than he wants to put up with, but if you do use it with nolva as Mr X suggested use 60mg instead of 40mg/day. That's the medical protocol most endo's follow for gyno.
M
Mr.X
Guest
tempest2003 said:
That is more then sufficient. You shouldn't have any gyno worries with those dosages bro. Don't add anymore AIs to the mix.
R
racoon_city
Guest
too much anti-e's will have negative afects, just start at a sane dose IMO
macrophage69alpha
New member
tempest2003 said:
its really not necessary to stack them, however at the end of your letro use it would be ideal to use either aromasin or AIFM (since they are suicidal inhibitors) to stop oestrogen rebound that can occur with competitive inhibitors like letro or arimidex.
macrophage69alpha said:
From reading I would say the facts are Letro is the strongest. Aromasin would be up there also. But, from experience I like aimidex because I'm afraid of lowering estrogen levels too much because of the impact on blood lipids and for fear of sexual side effects related to having too little estro. Not being prone to gyno is there any reason for someone to switch from airimidex to aromasin on say for example a test only cycle at or above 750 mg/wk (not exceeding 1g) for over 12 weeks. Also, cardio has always been effective in this case for controlling water retention.
M
Mr.X
Guest
g mac said:
Stick to arimidex, 1mg ED should be plenty for you on a 750mg test cycle.
Arimidex is being shoved aside for no reason. It's been used for years at much lower dosages, .25mgs ED with great results. It's a potent anti-estrogen compound, and it works well.
informed09
New member
So should you use A-dex during cycle and switch to AIFM during PCT? Am I getting this right. Seems like we have some conflicting veiws. Help me understand please. Thanks guys
M
Mr.X
Guest
informed09 said:
arimidex during the cycle, and clomid or nolvadex for PCT. HCG might also be needed PCT depending on cycle.
macrophage69alpha
New member
informed09 said:
if you are going to use a competitive inhibitor, you should follow it with ( at least a short course) a suicidal inhibitor (either aromasin or AIFM) to stop oestrogen rebound.
informed09
New member
Thanks macro thats what I was wondering! K to youmacrophage69alpha said:
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