I am going to semi hijack this thread because I was just about to post this very question. It sounds like what I am dealing with, and mine is lower back a few inches above the buttcrack. At first I thought it was my kidneys but I am not taking any orals, only injects. I would rest it and it would be ok. I THINK mine may be related to my increased intensity when working out, and lower back soreness. There do seem to be some "wierdness" deep inside, say around my prostate, bladder, lowerback kinda thing. It doesn't hurt really, I just notice it sometimes except when I am working out. That leads me to beleive it is muscle related since they get warm and do not hurt. I am taking milk thistle, saw palmetto, drink at least 3/4ths of a gallon each day usually a full gallon as well as a multi and glucosamine. So, I too will send out some karma to anyone that can help us out.