Some Evidence Please

[The Iron Game]

I have often read you wish to keep blood plasma levels of a product x as constant and stable as possible to allow for continious growth. I have also read by doing this side effects will be less. What evidence is to suggest that injecting 1000mgs of enanthate once every 7 days as oppossed to once 500mgs every 3.5 days will give a person less sides?

Peace

 

[Nathan]

Great question IG. I have never read of any "evidence", only theory and conjecture.

 

[21inch_arms]

I have often read you wish to keep blood plasma levels of a product x as constant and stable as possible to allow for continious growth. I have also read by doing this side effects will be less. What evidence is to suggest that injecting 1000mgs of enanthate once every 7 days as oppossed to once 500mgs every 3.5 days will give a person less sides?

Peace

The only evidence available would be possibly liver enzyme counts. I know that when I was on the "Gram-a-bol" cycle (1g or Test Enan. PW and 75mg of methandienone ED) last year, my liver enzyme count would have a roller coaster effect. Although I'm sure it had a lot to do with the D-bol my liver Enzyme count would elevate from around 40 to 90 SGPT (I believe). My d-bol intake was consistent at 75mg per day but the Enanthate was injected on a weekly basis. I took blood samples EOD for the duration of the 6-week cycle. I'll look and ask around and see if there's any documented information.

 

[The Iron Game]

Thanks 21inch_arms as you mentioned this was more likely the result of the dbol but so far I have seeb numerous people say inject more frequently and keep the side effects down. Bumping for them to chime in

 

[needleboy]

IG-

I inject numerous times, cause I'd have to inject around 6-7ccs at once if I didn't. 3 s quite enough thank you. AS for keeping levels stabil, I have made great gains on low dose cycles shooting 1 time per week!!!

Hell my first cycle was 200mg/wk Prop & 100 mg/wk deca and I gained 25 lb shooting 1 time per week.

 

[JG1]

Bump

 

[The Iron Game]

Andy13, Stew Meat ?

 

[The Iron Game]

Needleboy, I hear what you are saying, right now I just wanna get to the bottom of this inject more frequently = less sides issue

Peace

 

[micke]

yea thats tru iron i inj 3-4 times a day...lol whit awsame results.

 

[The Iron Game]

Micke does your Turkish friend help you hahaha

 

[micke]

ha ha ha thats funny shit,you make me cry

 

[CONTRACTION]

I inject sust eod, I'm on week 5 and I have no sides...no signs of gyno, acne, etc.

I know that doesnt prove anything, but just to add in my experience to your post...

 

[CONTRACTION]

Oh and on top of that spacing my dbol every 4 hrs for these first 5 weeks.

 

[The Iron Game]

Who started this rumour or maybe not but no one has spoken?

Contraction I can see where you are coming from but you cannot really say sust eod instead of 500mgs every 4th day will give you any less sides

Peace

 

[CONTRACTION]

Nope, it's not evidence, just input.

 

[The Iron Game]

I know thanks

 

[zen42]

Iron,

I'm surprised at you...Don't you know the biggest guy in the gym is always right? What more evidence do you need? After all, he wouldn't be so big if he didn't know what he was doing!

Oh... if you're asking online it's the person with the most posts, too.


Zen

 

[Andy13]

IG- I'm doubt if there is any "clinical" evidence about this..

But you do agree that more frequent injections= more even blood concentration, right?

Well look at drugs like test suspesion compared to test enanthate.. MOst will tell you that there are many more sides that come with suspension. That is because, even if it is injected ED, blood levels fluctuate wildly.

A rational theory for fluctuating blood levels=more sides my be the "spillover theory"

That says that spikes in blood levels are more than what the present ARs can "handle" and more spillover into other receptors and enzymes happens.

THis is the likely cause of excess sides with suspension...

Say for instance you inject 500mg/week of test enanthate.. After enough injections have accumulated, you max out to between 50-90mg of test being through the system per day. This degree of variation decreases as the injections are made more frequent (as I have shown in my mathematical look at injection frequency thread).

When someone injects 100mg of suspension, a much, much greater amount of test goes through the system in one day as compared with 500mg/week enanthate. This amount is less than what the AR's are able to be saturated with and more test is available to bind other enzymes (aromatase) and receptors PR's.

With enanthate, It is very likely that up-regulation happens, at least transietly with the slow duration of enanthate. This is initially due to the increased half life of the AR as a result of a bound substrate.

This is not the case with suspension.. The saturation happens so fast and is gone quickly that it does not yeild nearly the same transcriptional upregulation of the AR gene as a longer acting test does.

these are just my thoughts.. hope this helps shed some light on it..

Andy

 

[Andy13]

I'd like to hear some more thoughts...

 

[The Iron Game]

Andy, thanks for your input. I can see where you are coming from but also see a few flaws in what you have said. I havent got much spare time right now but no doubt in the near future you will be hearing from me on this subject.

Peace