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Renewtrient are they around again?
- Thread starter bilpax
- Start date
From http://www.renewtrient.com
Finally Renewtrient II is here and now called Tranquili-G- for the ultimate in relaxation and sleep choose Renewtrient II.
Distributor's or Retailer's Please Email [email protected] for Pricing and More Information.
Renewtrient II (Tranquili-G)
Regular price: $79.99
Sale price: $69.99
This is what I found, don't really know if it the same...
Finally Renewtrient II is here and now called Tranquili-G- for the ultimate in relaxation and sleep choose Renewtrient II.
Distributor's or Retailer's Please Email [email protected] for Pricing and More Information.
Renewtrient II (Tranquili-G)
Regular price: $79.99
Sale price: $69.99
This is what I found, don't really know if it the same...
Tranquili-G (patent pending) is a breakthrough sleep-aid/mood-enhancer, which, upon ingestion, is converted by the body into a GHB analogue that has been found to bind to the receptor with 15% greater affinity than GHB itself. And, unlike 1,4 butanediol, it is perfectly legal for human consumption. It is also naturally occurring and on the FDA's "Generally Regarded as Safe (G.R.A.S.) list.
Tranquili-G is the tradename for 4-pentanolide (patent pending). Upon ingestion, Tranquili-G is converted via lactonase catalyzed hydrolysis -- the same mechanism by which GBL is converted to GHB (1) -- to the potent GHB analogue, 4-methyl-GHB . 4-methyl-GHB has been found to bind to the GHB receptor with 15% GREATER affinity than GHB itself . Gamma-hydroxybutyrate exerts its effects through specific GHB receptors , thus consumption of a precursor to a compound which binds to the GHB receptor would be expected to result in physiological and psychological effects quite similar to those produced by GHB, such as sedation, reduction of anxiety, and stimulation of growth hormone release.
Tranquili-G is a naturally occurring compound -- -- found in such things as beef, beer, cocoa, coffee, mushrooms, peaches, peanuts, wheat bread, heated butter, and honey. It is perfectly legal for sale and human consumption and already enjoys widespread use as a flavoring agent in candy, meat products, and baked goods. It is on both the FDA's and the Flavor and Extract Manufacturers Association's (FEMA) Generally Regarded as Safe (G.R.A.S) lists. In addition, it is extremely non-toxic, with an LD50 (the dose that kills 50% of subjects) of 8.8g/kg (4) - this is 200-300 times the effective dose. For comparison, GBL, which is also quite non-toxic, has an LD50 of less than 2g/kg .
Tranquili-G is the tradename for 4-pentanolide (patent pending). Upon ingestion, Tranquili-G is converted via lactonase catalyzed hydrolysis -- the same mechanism by which GBL is converted to GHB (1) -- to the potent GHB analogue, 4-methyl-GHB . 4-methyl-GHB has been found to bind to the GHB receptor with 15% GREATER affinity than GHB itself . Gamma-hydroxybutyrate exerts its effects through specific GHB receptors , thus consumption of a precursor to a compound which binds to the GHB receptor would be expected to result in physiological and psychological effects quite similar to those produced by GHB, such as sedation, reduction of anxiety, and stimulation of growth hormone release.
Tranquili-G is a naturally occurring compound -- -- found in such things as beef, beer, cocoa, coffee, mushrooms, peaches, peanuts, wheat bread, heated butter, and honey. It is perfectly legal for sale and human consumption and already enjoys widespread use as a flavoring agent in candy, meat products, and baked goods. It is on both the FDA's and the Flavor and Extract Manufacturers Association's (FEMA) Generally Regarded as Safe (G.R.A.S) lists. In addition, it is extremely non-toxic, with an LD50 (the dose that kills 50% of subjects) of 8.8g/kg (4) - this is 200-300 times the effective dose. For comparison, GBL, which is also quite non-toxic, has an LD50 of less than 2g/kg .
Here is some info that I found:Tranquili-G is the tradename for 4-pentanolide (patent pending). Upon ingestion, Tranquili-G is converted via lactonase catalyzed hydrolysis -- the same mechanism by which GBL is converted to GHB (1) -- to the potent GHB analogue, 4-methyl-GHB (see *). 4-methyl-GHB has been found to bind to the GHB receptor with 15% GREATER affinity than GHB itself (2). Gamma-hydroxybutyrate exerts its effects through specific GHB receptors (3), thus consumption of a precursor to a compound which binds to the GHB receptor would be expected to result in physiological and psychological effects quite similar to those produced by GHB, such as sedation, reduction of anxiety, and stimulation of growth hormone release.
Tranquili-G is a naturally occurring compound -- -- found in such things as beef, beer, cocoa, coffee, mushrooms, peaches, peanuts, wheat bread, heated butter, and honey. It is perfectly legal for sale and human consumption and already enjoys widespread use as a flavoring agent in candy, meat products, and baked goods. It is on both the FDA's and the Flavor and Extract Manufacturers Association's (FEMA) Generally Regarded as Safe (G.R.A.S) lists. In addition, it is extremely non-toxic, with an LD50 (the dose that kills 50% of subjects) of 8.8g/kg (4) - this is 200-300 times the effective dose. For comparison, GBL, which is also quite non-toxic, has an LD50 of less than 2g/kg (5).
Real World Effects
As we are getting more feedback, it is becoming apparent that the subjective effects of Tranquili-G and GHB/GBL are not identical. It seems that this product does not produce a "high" quite the way GBL and GHB do -- particularly that weird feeling in the front of the head. Instead, it seems to be more of a mental and physical anxiolytic effect (basically, you feel very relaxed and happy, but not "fucked up" -- kind of like with Xanax or Valium). There also seems to be a definite plateau -- meaning 2.5 to 5ml produces as much of an effect as 10-15ml, and it seems to last longer than GHB or GBL. I am not completely certain why this is -- perhaps absorbtion or transport accross the blood brain barrier becomes saturated (this is the case for GHB, though apparently at a higher dose). This lack of ups and downs has its advantages and disadvantages. At this point, I consider it superior as an anxiolytic/anti-depressant -- one could truly take it throughout the day and just feel relaxed and pleasant, but quite functional as you do not get trashed and you do not crash. I consider it superior as a night time sleep aid because it lasts longer -- you do not jolt awake at 4:00 in the morning from a dopamine rush like with GHB. However, because the effects plateau, this will not knock you out, which could be considered as a negative. I have to say that, though I personally like it better, I think most people will consider it inferior as a "party drug", because, as I mentioned before, you do not get wasted from it. However, early reports are that, in combination with alcohol, you can become quite enebriated. Each 4oz bottle contains 24-48 servings.
Tranquili-G is a naturally occurring compound -- -- found in such things as beef, beer, cocoa, coffee, mushrooms, peaches, peanuts, wheat bread, heated butter, and honey. It is perfectly legal for sale and human consumption and already enjoys widespread use as a flavoring agent in candy, meat products, and baked goods. It is on both the FDA's and the Flavor and Extract Manufacturers Association's (FEMA) Generally Regarded as Safe (G.R.A.S) lists. In addition, it is extremely non-toxic, with an LD50 (the dose that kills 50% of subjects) of 8.8g/kg (4) - this is 200-300 times the effective dose. For comparison, GBL, which is also quite non-toxic, has an LD50 of less than 2g/kg (5).
Real World Effects
As we are getting more feedback, it is becoming apparent that the subjective effects of Tranquili-G and GHB/GBL are not identical. It seems that this product does not produce a "high" quite the way GBL and GHB do -- particularly that weird feeling in the front of the head. Instead, it seems to be more of a mental and physical anxiolytic effect (basically, you feel very relaxed and happy, but not "fucked up" -- kind of like with Xanax or Valium). There also seems to be a definite plateau -- meaning 2.5 to 5ml produces as much of an effect as 10-15ml, and it seems to last longer than GHB or GBL. I am not completely certain why this is -- perhaps absorbtion or transport accross the blood brain barrier becomes saturated (this is the case for GHB, though apparently at a higher dose). This lack of ups and downs has its advantages and disadvantages. At this point, I consider it superior as an anxiolytic/anti-depressant -- one could truly take it throughout the day and just feel relaxed and pleasant, but quite functional as you do not get trashed and you do not crash. I consider it superior as a night time sleep aid because it lasts longer -- you do not jolt awake at 4:00 in the morning from a dopamine rush like with GHB. However, because the effects plateau, this will not knock you out, which could be considered as a negative. I have to say that, though I personally like it better, I think most people will consider it inferior as a "party drug", because, as I mentioned before, you do not get wasted from it. However, early reports are that, in combination with alcohol, you can become quite enebriated. Each 4oz bottle contains 24-48 servings.
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