Science says it´s possible to treat gynecomastia with tamoxifen PO and DHT gel with success. Not everybody will benefit, but I really think tamoxifen worths a shot. If lypomastia is a part of the problem, then maybe some yohimbine gel would help.
Comparison of tamoxifen with danazol in the management of idiopathic gynecomastia.
Ting AC - Am Surg - 01-JAN-2000; 66(1): 38-40
From NIH/NLM MEDLINE
Authors:
Ting AC; Chow LW; Leung YF
Abstract:
Idiopathic gynecomastia, unilateral or bilateral, is a common physical finding in normal men.
Successful treatment using tamoxifen (antiestrogen) and danazol (antiandrogen) has recently been reported. We compared the efficacy of tamoxifen and danazol in the treatment of idiopathic gynecomastia.
Medical treatment with either tamoxifen (20 mg/d) or danazol (400 mg/d) was offered and continued until a static response was achieved. The treatment response was compared. Sixty-eight patients with idiopathic gynecomastia were seen in the Breast Clinic. The median age was 39.5 years (range, 13-82), with a median duration of symptoms of 3 months (range, 1-90). The median size was 3 cm (range, 1-7).
Complete resolution of the gynecomastia was recorded in 18 patients (78.2%) treated with tamoxifen , whereas only 8 patients (40%) in the danazol group had complete resolution. Five patients, all from the tamoxifen group, developed recurrence of breast mass.
. In conclusion, hormonal manipulation is effective in the treatment of patients with idiopathic gynecomastia.
Although the effect is more marked for tamoxifen compared with danazol, the relapse rate is higher for tamoxifen. Further prospective randomized studies would be useful in defining the role of these drugs in the management of patients with idiopathic gynecomastia.
DHT :
1-Eberle A, Sparrow J, Keenan B. 1986 Treatment of persistent pubertal gynecomastia with dihydrotestosterone heptanoate. J Pediatr. 109-144.
2- Kuhn JM, Roca R, Laudat MH, Rieu M, Luton JP, Bricaire H. 1983 Studies on the treatment of ideopathic gynecomastia with percutaneous dihydrotestosterone. Clin Endocrinol (Oxf). 19:513-520.
3-Successful percutaneous dihydrotestosterone treatment of gynecomastia occurring during highly active antiretroviral therapy: four cases and a review of the literature.
Benveniste O - Clin Infect Dis - 15-Sep-2001; 33(6): 891-3
From NIH/NLM MEDLINE