Please Scroll Down to See Forums Below 
Burning_Inside
Elite Mentor
just wondering if any and if so how much
r-ala on refeed days?
- Thread starter Burning_Inside
- Start date
Ceebs
New member
Yes, yes, YES! R-ALA greatly improves glycogen storage, and diminishes bloat the day after. The formula for doses is generally 100mg per every 30 grams of carbs, although if you graze all day, you may want to take a specific amount every few hours regardless of what/how much you eat.
What works for me personally (female, 138 lbs, ~15% bodyfat) is to take 200mg every 3-4 hours. I tried doing smaller amounts more frequently, and larger amounts less frequently, and 200mg is my happy zone.
What works for me personally (female, 138 lbs, ~15% bodyfat) is to take 200mg every 3-4 hours. I tried doing smaller amounts more frequently, and larger amounts less frequently, and 200mg is my happy zone.
MrMakaveli
New member
this all makes sense but I was reading old posts by Par who said that refeeds at night would cause a better rise in leptin due to a greater nutrient flux through fat cells. Since R-ALA shuttles nutrients toward muscle does this at all decrease the desired leptin effects?
Senior Woonaki
New member
good question!
bump it up....
bump it up....
MrMakaveli
New member
bump for answers
Burning_Inside
Elite Mentor
Shinobi said:
according to the test by fonz "For meals with carb contents at of below 108 grams:
11.11mg of racemic ALA per 1 gram of carbohydrates
3.7mg of R-ALA per 1 gram of carbohydrates
If the carb content of the meal goes beyond 108g the R-ALA loses effectiveness at an ever-increasing rate, but still manages to be 55% more effective (mg per mg) than racemic ALA. To use an analogy, R-ALA is like a scalpel while ALA is like a kitchen knife. They will both work, but for cutting I would go with R-ALA, and for bulking I would consider racemic ALA if I could not afford R-ALA because of the cost."
The difference is that r-ALA works and the regular ALA doesn't unless you take big piles of it in order to get the a few minutes worth of benefit that comes from the r-ALA in it. Because r-ALA works 28 times faster you get a bump of r-ALA from the regular until the s-ALA in it starts to shut it down. There is a thread at the top of the board.
JJFigure
New member
I was doing my own r-ala research and came across the same study that's posted as a sticky. However, one of the negative effects is missing from the sticky:
Negative Results and Limitations
"For 6 wk, lean Zucker rats either remained sedentary, received R-ALA (30 mg. kg body wt(-1). day(-1)), performed exercise training (ET - treadmill running), or underwent both R-ALA treatment and ET. ET alone or in combination with R-ALA significantly increased (P < 0.05) peak oxygen consumption (28-31%) and maximum run time (52-63%). During an oral glucose tolerance test, ET alone or in combination with R-ALA resulted in a significant lowering of the glucose response (17-36%) at 15 min relative to R-ALA alone and of the insulin response (19-36%) at 15 min compared with sedentary controls. Insulin-mediated glucose transport activity was increased by ET alone in isolated epitrochlearis (30%) and soleus (50%) muscles, and this was associated with increased GLUT-4 protein levels. Insulin action was not improved by R-ALA alone, and ET-associated improvements in these variables were not further enhanced with combined ET and R-ALA. Although ET and R-ALA caused reductions in soleus protein carbonyls (an index of oxidative stress), these alterations were not significantly correlated with insulin-mediated soleus glucose transport. These results indicate that the beneficial interactive effects of ET and R-ALA on skeletal muscle insulin action observed previously in insulin-resistant obese Zucker rats are not apparent in insulin-sensitive lean Zucker rats."R
"we only observed a beneficial effect of [RLA] only in old and not in young animals."R
"The decline observed in the plasma concentration was steep (t1/2, 0.5 h)"R. ie RLA or RSLA have short plasma half-lives.
RLA did not improve "longer-term memory ... in the habituation in the open field test at a dose of 100 mg/kg body weight for 15 days ... for young mice"R.
The last sentence of the first negative effect is the key one that made me rethink adding this supplement to my list:
Here's the link to the full article:
http://morelife.org/supplements/RLA.html
Negative Results and Limitations
"For 6 wk, lean Zucker rats either remained sedentary, received R-ALA (30 mg. kg body wt(-1). day(-1)), performed exercise training (ET - treadmill running), or underwent both R-ALA treatment and ET. ET alone or in combination with R-ALA significantly increased (P < 0.05) peak oxygen consumption (28-31%) and maximum run time (52-63%). During an oral glucose tolerance test, ET alone or in combination with R-ALA resulted in a significant lowering of the glucose response (17-36%) at 15 min relative to R-ALA alone and of the insulin response (19-36%) at 15 min compared with sedentary controls. Insulin-mediated glucose transport activity was increased by ET alone in isolated epitrochlearis (30%) and soleus (50%) muscles, and this was associated with increased GLUT-4 protein levels. Insulin action was not improved by R-ALA alone, and ET-associated improvements in these variables were not further enhanced with combined ET and R-ALA. Although ET and R-ALA caused reductions in soleus protein carbonyls (an index of oxidative stress), these alterations were not significantly correlated with insulin-mediated soleus glucose transport. These results indicate that the beneficial interactive effects of ET and R-ALA on skeletal muscle insulin action observed previously in insulin-resistant obese Zucker rats are not apparent in insulin-sensitive lean Zucker rats."R
"we only observed a beneficial effect of [RLA] only in old and not in young animals."R
"The decline observed in the plasma concentration was steep (t1/2, 0.5 h)"R. ie RLA or RSLA have short plasma half-lives.
RLA did not improve "longer-term memory ... in the habituation in the open field test at a dose of 100 mg/kg body weight for 15 days ... for young mice"R.
The last sentence of the first negative effect is the key one that made me rethink adding this supplement to my list:
Here's the link to the full article:
http://morelife.org/supplements/RLA.html
The studies on rats vary quite a bit. The studies on humans however do not vary. r-ALA is 6 rimes as potent and 28 times faster than s-ALA in studies done on human cells in vitro as well.
This study you posted used juvenile rats and it's results were already proven in other studies. Exo r-ALA doesn't have much affect on human children either, mainly because their bodies already make so much r-ALA already.
If you give a 2 years old a bowl of Ice Cream, the child will be bouncing off the walls in a short time. If you give the same bowl of Ice Cream to a 40 year old, the 40 year will be asleep on the couch in a short time. The 2 year old's producing much more r-ALA to begin with.
This study you posted used juvenile rats and it's results were already proven in other studies. Exo r-ALA doesn't have much affect on human children either, mainly because their bodies already make so much r-ALA already.
If you give a 2 years old a bowl of Ice Cream, the child will be bouncing off the walls in a short time. If you give the same bowl of Ice Cream to a 40 year old, the 40 year will be asleep on the couch in a short time. The 2 year old's producing much more r-ALA to begin with.
