Questions about T3

[Lao Tzu]

This is what i understand about T3:

10 hour half life

body needs 35-50mcg of T3 a day for 'normal' functioning

dieting causes the enzyme that converts T4 into T3 to not work as well

Hypothyroidism is not due to 0% T3 production, but production that is only about 60% as high as it should be


alright. Im going to increase calories on my diet to about 3200, but i dont think it will be enough. And i dont have alot of faith in stuff like selenium to compensate fully so i want to start augmenting with T3. HOWEVER, i do not want to shut my own thyroid down and i do not want to supercharge my metabolism. I just want my metabolic rate to be normal, even 90% of normal is acceptable.

Since it takes 35-50mcg a day for normal metabolic functions, and i assume i am making 25-35mcg a day, would a 12.5mcg dose combined with thyroid meds like selenium cause any shutdown of my own thyroid? I would assume those 2 combinations (12.5mcg T3 and selenium) might bring my T3 levels up to about 45mcg a day, which is essentially normal. However i am pretty sure ive heard from people knowledgable about T3 that 12.5mcg doesn't do anything. Maybe they said 12.5 doesnt shut down the thyroid. i dont know.

Also, would i need to taper up and down if i used 12.5mcg? Like would i need 6.25mcg for a week before and after i do the T3 or would the changes be negligible enough to not matter?

Also, due to the 10 hour half life do you dose twice daily or just once in the morning?

i dont know if my thyroid is screwing up or not, but i figure its better to experiment and see than to do nothing.

 

[Lao Tzu]

odd

http://www.rxlist.com/cgi/generic3/liothyronine_cp.htm

That site says a 2.5 day half life. Shit. dosing based on a 10 hour half life if the drugs has a 2.5 day half life could lead to an extremely high dosage.

 

[Lao Tzu]

http://www.t-mag.com/html/body_117chem.html

Personally, I radically advocate going in the opposite direction — I like to see doses as low as 12.5 mcg/day. Here, natural thyroid production isn't reduced much. You get most of the benefits, and almost none of the adverse effect. Using this dosage, you should be able to lose 3 lb of fat per week, or close to it, with no problem… if all else in the diet and exercise program is good.

Taking the 12.5 mcg/day dose level actually results in about 50 mcg of drug in your system, because T3 (Cytomel) has a long half life and your system doesn't contain just the amount you took today, but also about three times more than that left over from previous days. For this reason, I'd take a 50 mcg loading dose the first day (if I knew I handled T3 well), and then maintain that level with 12.5 mcg/day after that. If it were my first use, though, I'd let levels build up slowly instead of taking the loading dose.


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So maybe i can try either a 50mcg loading dose and 12.5mcg subsequent daily dose, or a 37.5:9.375, or a 25:6.25 doseage schedule

 

[OXANDRIN]

I used T3 to help treat my borderline personality disorder...... The shit worked well at 50mcg ED

 

[Deleted member 33117]

I would actually start at 12.5 mcg every day (that is what I've been prescribed) and see if it does the trick before increasing to 25 mcg. 50 mcg a day is not what is needed for normal function unless you had a sever thyroid problem. People given those type of doses weigh 350 ibs on a 1500 calories diet prior to treatment.

 

[Fonz]

http://www.t-mag.com/html/body_117chem.html

Personally, I radically advocate going in the opposite direction — I like to see doses as low as 12.5 mcg/day. Here, natural thyroid production isn't reduced much. You get most of the benefits, and almost none of the adverse effect. Using this dosage, you should be able to lose 3 lb of fat per week, or close to it, with no problem… if all else in the diet and exercise program is good.

Taking the 12.5 mcg/day dose level actually results in about 50 mcg of drug in your system, because T3 (Cytomel) has a long half life and your system doesn't contain just the amount you took today, but also about three times more than that left over from previous days. For this reason, I'd take a 50 mcg loading dose the first day (if I knew I handled T3 well), and then maintain that level with 12.5 mcg/day after that. If it were my first use, though, I'd let levels build up slowly instead of taking the loading dose.


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So maybe i can try either a 50mcg loading dose and 12.5mcg subsequent daily dose, or a 37.5:9.375, or a 25:6.25 doseage schedule

Thats the best option. That dosage will only slightly reduce TSH levels. Therefore, if you come off T3, you won't get any kind of rebound effect.

 

[Lao Tzu]

Thats the best option. That dosage will only slightly reduce TSH levels. Therefore, if you come off T3, you won't get any kind of rebound effect.

Yeah, plus i will take tyrosine, guggulsterones & selenium, so my normal thyroid will hopefully be more able to cope with the influx of artificial thyroid.

 

[Slyder190]

Fonz you look SICK bro!

 

[Fonz]

Fonz you look SICK bro!

Apparently that pic is photoshopped too.....lol

I would pay $1000 if all the guys bashing me(about 30) about how small I am...lol would all line up and take pics. I want to see just how "jacked", and "Buff" they really are....lol Most likely never seen the under-side of 15% BF.

 

[Fonz]

Lets see if I can finally post a pic:

 

[Lao Tzu]

nice that you've managed to keep your weight training & diet in order while doing a Ph.D. in a hard subject. Alot of people end up gaining alot of weight when they go to grad school.

how is that working out? You still passing? How many more years you got, 4.5?

 

[Fonz]

nice that you've managed to keep your weight training & diet in order while doing a Ph.D. in a hard subject. Alot of people end up gaining alot of weight when they go to grad school.

how is that working out? You still passing? How many more years you got, 4.5?

Done right, bodybuilding gives you a great degree of discipline that transfers over to almost all areas of your life. Its a 24/7 endeavour...you need to be consistent and very determined to succed...which applies to everything in life.

I have 3 more years for my grad degree. I'm going to take an off year to really concentrate on my thesis. So total 4. I want to write a really good original thesis. Hard to do, specially in the Nuclear field. And is going to require a lot of research and special permits to access documents that are restricted to normal people. (Its like a very in depth background check that is performed on you and you get a security clearance,the lowest actually..lol) I just want access to documents regarding tests(fusion bombs) done in the 50's and 60's and 70's regarding ) Its definately going to be a challenge to say the least.

After that...I'm undecided if I want to get into the university environment again (Ph. D) or just get to wotk. Probably The Department of Energy, Nuclear Energy Division.

 

[Deleted member 33117]

Hmmmm.... I'm reasonably big and am on the underside of 15%. Then again, I really don't give you a hard time either. Oh well. Two out of three isn't bad though. Anywho when I finish up my masterone/tren/winstrol stack (I'll start it in about 2 weeks) I'll snap pics this summer.