Question on receptors

[mytmo]

I was wondering if our bodies have diferent receptors for diferent AS. Ive only done 5 cycles and in this time when ever I get to about week 7-8 I feel as if Im no longer feeling it as much as say in week 3-5. So in all if I were to switch gear at week 7 say from fina to test or deca are their receptors still available to accept this new AS. Dont mean to sound ignorant, Ive just been listening to what my body has been telling me and I would likee to run something a little longer than 8 weeks and still reep the benefits. Once again this is just how my body is reacting. Thanks again for all your help.

 

[Beezers]

All anabolic steroids use the same receptor...the Androgen Receptor. However the differences in AS are due to non-androgen receptor mediated effects. Testosterone, for example, is an antagonist of glucocorticoid receptors and thus interferes with cortisol induced catabolism. EQ seems to stimulate erithropyoyesis(sp) better that others. Different AS have different effects on blood glucose and glycogen synthesis. This is where the differences between different steroids come from, not from the receptor they use.

 

[djdjdjddjon]

uh, i dunno there. various compounds do fit in various receptors,(yes they are all androgen receptors but their not identical) different testosterone derivitives are different molecules completely, how can one fit in anothers receptor? it makes no sense, so roughly around weeks 6-8 in theory you could switch up the test or its derivitive and fresh receptors would be free...from my understanding. $.02

 

[lawnsaver]

uh, i dunno there. various compounds do fit in various receptors,(yes they are all androgen receptors but their not identical) different testosterone derivitives are different molecules completely, how can one fit in anothers receptor? it makes no sense, so roughly around weeks 6-8 in theory you could switch up the test or its derivitive and fresh receptors would be free...from my understanding. $.02

Absolutelty incorrect. Why would an ester have anything to do with the base of test??

There is only the A/R and there are billions of them!

 

[lawnsaver]

Repost-Stacking opposing classes of anabolics for maximum efficiency... (post #1)

For all my brotha's getting ready to put together those winter bulking regimens,thought this might come in handy for you...

Anabolic Steroids achieve their effects on hypertrophy through different mechanisms,and as such are classified into two different categories,class-I and class-II compounds.I will explain which ones work through which pathway,and how to effectively combine opposing groups to maximize potentiation of one another for explosive growth....

Class-I-These are steroids who's primary influence on anabolism is achieved through aggressive binding and activation of the androgen receptor...Examples of potent class-I's are-Deca-durabolin,primobolan,equipoise,oxandrolone...

Class-II-These are compounds with potent activity independent of A/R binding/activation,and their activity has been monitored in neuron's,microsomes,mitochondria,etc...Examples of potent class-II's are-Anadrol,Dianabol,winstrol,Fluoxymesterone...

Then we have steroids that are potent combination steroids all by themselves(meaning they display influences on growth through both class-I and II activity,and thus are very effective as'stand-alone'anabolic agents as well as forming the 'base' of most steroid stacks)....Two compounds possess this unique characteristic-Trenbelone and Testosterone.Either of these two steroids should form the base of most users stacks,as the cover both A/R and non-A/R mediated mechanisms,and adding to them with either a class-I or II will only potentiate that particular mechanism towards muscular hypertrophy...

Now that we're aware of which compounds work through which mechanism,how do we combine them effectively to maximize each one's potential?As explained above,Testosterone and trenbelone should form the base of any serious steroid stack,but great effects can be had by combining single mechanism steroids from opposing classes....Examples of this type of synergistic combining could be(but are not limited to)

*CUTTING*
Winstrol & Equipoise
Winstrol & Primobolan
Fluoxymesterone & Equipoise or Primobolan

*BULKING*
Deca & Dianabol
Anadrol & Equipoise or Primobolan
Winstrol & deca

And of course,using test or tren as the base compound for either cutting or bulking will only make results that much more explosive.If using test for cutting,an anti-aromitase should be incorporated...