Question about r-ALA.......

[emptywallet]

Im currently using 60g of dextrose post workout. If I took say 300mgs of r-ALA with that could shoudl I increase the amount of dextrose any?

 

[macrophage69alpha]

Im currently using 60g of dextrose post workout. If I took say 300mgs of r-ALA with that could shoudl I increase the amount of dextrose any?

yes or use less r-ala

btw-

age?

and current insulin resistance. ie do you deal well with carbs, do you get big insulin spikes, lethargy, do carbs make you fat?

 

[emptywallet]

Re: Re: Question about r-ALA.......

yes or use less r-ala

btw-

age?

and current insulin resistance. ie do you deal well with carbs, do you get big insulin spikes, lethargy, do carbs make you fat?

After I have any big meal, I tend to get tired. This is only with large meals though. I'm not sure if its carb dependant or not, since I get little sleep at night because of school, it is possible that I'm just tired from that. Actaully now that I think of it I was sleeping good this summer, ate quite a few carbs then and I never really felt lethargic. So no I dont think I get lethargic from them. If I drop the carbs to far though I tend to feel like complete crap, but thats only for a little while and then I get used to it. I'm 22 right now. I'm sure carbs at some point will make me fat, if I consume to many of them.

 

[macrophage69alpha]

with people in your age group r-ala effects and dosages are less well defined.. you will have to play around a bit to see what works..

vary the post workout carbs as well as the r-ala dosages to see what you respond best too.

 

[macrophage69alpha]

 

[Frackal]

Macro, the more insulin sensitive you are...woudl that mean you would need to add MORE r-ala to see a difference or you dont need as much because you are already fairly sensitive?

 

[TraxZBT]

Re: Re: Question about r-ALA.......

yes or use less r-ala

btw-

age?

and current insulin resistance. ie do you deal well with carbs, do you get big insulin spikes, lethargy, do carbs make you fat?

I don't understand. Carbs make me EXTREMELY lethargic, almost to the point of passing out. Does this mean i'm sensitive or insensitive? Can R-ALA help this in any way? Sorry for asking a question within your post EmptyWallet, but this has been bothering me for some time and just need a quick answer.

BTW i'm 20 years old if it matters.

 

[macrophage69alpha]

Macro, the more insulin sensitive you are...woudl that mean you would need to add MORE r-ala to see a difference or you dont need as much because you are already fairly sensitive?

it depends.. a lot... there are a lot of factors to take into account.. will post something more comprehensive when time permits..

 

[macrophage69alpha]

Re: Re: Re: Question about r-ALA.......

I don't understand. Carbs make me EXTREMELY lethargic, almost to the point of passing out. Does this mean i'm sensitive or insensitive? Can R-ALA help this in any way? Sorry for asking a question within your post EmptyWallet, but this has been bothering me for some time and just need a quick answer.

BTW i'm 20 years old if it matters.

you are insensitive.. but you are, at least likely from your pic, what is called "androgen insensitive".. this is one of the factors mentioned above.. in your case higher end dosages 600mg to 1g PER DAY may be necessitated.

yes.. it is very likely that r-ala will help considerably..

 

[Frackal]

Just as a personal note, when using your ala I find that anything over 300mg and I go hypo even if taking in 600 calories of carbs (potato flakes, 2% cottage cheese)

 

[macrophage69alpha]

btw- a GREAT investment is a glucometer.. particularly if you have glucose problems.. that way you can measure what dosages (as well as meals, food , etc) are best for you..

its not essential but it is something that can be quite helpful..

 

[macrophage69alpha]

Just as a personal note, when using your ala I find that anything over 300mg and I go hypo even if taking in 600 calories of carbs (potato flakes, 2% cottage cheese)

age again?
is that on or off cycle?
taking yohimburn? this can affect secretion
aromatase inhibitor?
bodyfat?

just curious as that is interesting..

note- this is new for everyone(r-ala use in the atheletic arena, with and without AS) and a very individual issue (though there are trends).. so trial and error is often the best way to determine what works best for you..

 

[macrophage69alpha]

 

[icelandic]

What exactly do you mean by the term "androgen insensitive"? Do androgens play an important role in carbohydrate metabolism?

 

[macrophage69alpha]

What exactly do you mean by the term "androgen insensitive"? Do androgens play an important role in carbohydrate metabolism?

hormones affect a variety of systems, one being insulin sensitivity.

 

[icelandic]

you are insensitive.. but you are, at least likely from your pic, what is called "androgen insensitive"..

The clinical manifestations of AIS are undermasculinization and sexually ambigous genitalia. That body depicted in that guy's avatar hardly shows any signs of androgen insensitivity. I'm not trying to be confrontational here, but what exactly are you referring to?

 

[macrophage69alpha]

The clinical manifestations of AIS are undermasculinization and sexually ambigous genitalia. That body depicted in that guy's avatar hardly shows any signs of androgen insensitivity. I'm not trying to be confrontational here, but what exactly are you referring to?

his insulin sensitivity problem is due to androgenic influence...

not that he is insensitive to androgens.. though could see how that might be inferred from post..

 

[icelandic]

This is really intriguing me. Is there a correlation between androgen levels and insulin sensitivty ? i.e. do higher androgen levels (either endo or exo) influence insulin sensitivty in a negative manner? Are there any studies?

 

[macrophage69alpha]

This is really intriguing me. Is there a correlation between androgen levels and insulin sensitivty ? i.e. do higher androgen levels (either endo or exo) influence insulin sensitivty in a negative manner? Are there any studies?

it appears to be the ratios (with high andogrens= impaired insulin).. though the mechanism is still being explored..
the use of progestins will likely, and seems to, have a different effect (win being at least slightly anti progestenic)..

J Clin Endocrinol Metab 1998 Dec;83(12):4420-5 Related Articles, Links


Effects of methyltestosterone on insulin secretion and sensitivity in women.

Diamond MP, Grainger D, Diamond MC, Sherwin RS, Defronzo RA.

Department Obstetrics and Gynecology, Hutzel Hospital/Wayne State University School of Medicine, Detroit, Michigan 48201, USA.

The frequent coexistence of hyperandrogenism and insulin resistance is well established; however, whether a cause and effect relationship exists remains to be established. In this study we tested the hypothesis that short-term androgen administered to women would induce insulin resistance. To test this hypothesis, regularly menstruating, nonobese women were studied before and during methyltestosterone administration (5 mg tid for 10-12 days) by the hyperglycemic (n=8) and euglycemic, hyperinsulinemic (n=7) clamp techniques. Short-term methyltestosterone administration had no significant effects on the fasting levels of glucose, insulin, c-peptide, glucagon, or glucose turnover. During the hyperglycemic clamp studies, the mean glucose level during the final hour was 203+/-2 and 201+/-1 mg/dL in the methyltestosterone and control studies, respectively. The insulin response to this hyperglycemic challenge was slightly but not significantly greater during methyltestosterone treatment (first phase 59+/-8 vs. 50+/-8 microU/mL in controls; second phase 74+/-9 vs. 67+/-9 microU/mL in controls; total insulin response 133+/-16 vs. 117+/-15 microU/mL in controls). In spite of this, glucose uptake was reduced from the control study value of 10.96+/-1.11 to 7.3+/-0.70 mg/kg/min by methyltestosterone (P < 0.05). The ratio of glucose uptake per unit of insulin was also significantly reduced from a control study value of 14.3+/-1.4 to 9.4+/-1.3 mg/kg/min per microU/mL x 100 during methyltestosterone administration. In the euglycemic hyperinsulinemic clamp studies, insulin was infused at rates of 0.25 and 1.0 mU/kg/min to achieve insulin levels of approximately 25 and 68 microU/mL, respectively. During low-dose insulin infusion, rates of endogenous hepatic glucose production were equivalently suppressed from basal values of 2.37+/-0.29 and 2.40+/-0.27 mg/kg/min to 0.88+/-0.25 and 0.77+/-0.26 mg/kg/min in the methyltestesterone and control studies respectively. Whole body glucose uptake during low-dose insulin infusion was minimally affected. During the high-dose insulin infusion, endogenous hepatic glucose production was nearly totally suppressed in both groups. However, whole body glucose uptake was reduced from the control value of 6.11+/-0.49 mg/kg/min to 4.93+/-0.44 mg/kg/min during methyltestosterone administration (P < 0.05). Our data demonstrate that androgen excess leads to the development of insulin resistance during both hyperglycemic and euglycemic hyperinsulinemia. These findings provide direct evidence for a relationship between hyperandrogenemia and insulin resistance, and its associated risk factors for cardiovascular disease.

 

[icelandic]

fascinating, thank you

 

[Frackal]

Ah lets see, I believe it was while I was off cycle, age is 20 years old, phenotype is Ectomorph with a hint of mesomorph, naturally very lean, hard to put on mass but not incredibly hard, started out at 6' 155 lean.

Was using liquidex at .25mg a day at the time

Never been sensitive to carbs, diet is 4 primarily carb/protein meals in early part of day, 2 (until you ruined my ignorant bliss lol ) protein flaxseed meals night time, r-ala with the first 5 meals.

Taking yohimburn but not within 12 hours of the r-ala .. I woudl awaken, take the r-ala, eat potato flakes and 2 percent cottage cheese and whey, lie down for a 30 min nap before getting ready to train, when taking 400mg of the r-ala, I woudl get excessively sleepy with that hypo feeling...kind of hard to explain but I am sure it was hypo becaues after I awoke and showered my sugar would further drop and hand tremors would start

My bodyfat was probably about 7.5-8 percent, still is, bodyfat doesnt go much higher than say 11-12 percent no matter what...the old pics I've posted in the pics of members forum if anyone has seen them is the fattest that I get, that was during my first bulking cycle, towards the end. It seems I get to a certain bodyfat while bulking and then it just stops....I guess my natural GH years are coming to a close now so I should enjoy it while it lasts

 

[Frackal]

BTW Note that it seemed that the 300mg to 400mg jump was the point in which the excessive hypo was experienced, at 300mg I would get tremors and sleepiness off and on but at 400mg it would impede my training because I'd have to down carbs like crazy to feel normal about 2 hours after the r-ala potato/Cott. cheese mea

 

[macrophage69alpha]

ineresting..??