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Question about green tea (maybe Macro knows the awnser)
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macrophage69alpha
New member
very small amount typically less than 3% of weight and bioavailability will be poor. You are better of drinking green tea
bicepts101
New member
ohashi said:
exactly...
SUNDAY...do a search on green tea
i did a search on greentea and it gave me some information about it but i still dont kno enuf bout it.
is it good whilst on a bulking cycle?? (when i did the search it 1s said dat its good for loosing weight) I dont wanna loose weight, i wanna put some on,, so pls tell me if i shall drink it bcause, my mom buys it all da time and if im gna loose fat or weight then im not gna drink it.
tanx
is it good whilst on a bulking cycle?? (when i did the search it 1s said dat its good for loosing weight) I dont wanna loose weight, i wanna put some on,, so pls tell me if i shall drink it bcause, my mom buys it all da time and if im gna loose fat or weight then im not gna drink it.
tanx
bodytemple75
New member
Although mine had loads of sugar and crap in it, I like the "4c Green Tea" you can find in the supermarket. Far from supplement grade, I'm sure,... but between that and "Crystal Light" I enjoy drinking at home. Actually from what I am told the "Crystal Light" is not that bad for you. You don't digest it (sugar free) and has x amount of many calories which come out to some very small amount per serving. Almosy like drinking flavored water.
Sunday said:
Here you go, about 40% of my research on Green Tea. I've been compiling it:
Green tea works through BAT thermogenesis. Beta-3 adrenoreceptor activation. It has no effect on the thyroid.
Posted by BrooklynJuice: Long read...but well worth it.
The color (green, oolong, and black) of tea (Camellia sinensis) is determined by how it is manufactured. Green tea is prepared in such a way as to avoid the oxidation of the polyphenols; oolong tea is partially oxidized; black tea is largely oxidized.
The composition of tea is determined by soil conditions, the season the leaves are harvested, and the method used to process the tea. As a rough guide, green tea contains 2.9 to 4.2% caffeine, 0.02 to 0.04% theophylline, and 0.15 to 0.2% theobromine. Green tea also contains theanine, an important water-soluble amino acid that is converted to catechin by sun light. The greatest theanine content is found in the highest grade green tea, Gyokuro, which is cultivated without direct sunlight.
Green tea also contains a number of polyphenolic compounds. The catechin epigallocatechin gallate (EGCG) is the most abundant (> 50% of total tea catechins). It is also believed to be the most pharmacologically active. The other main catechins are epicatechin (EC), epicatechin gallate (ECG), and epigallocatechin (EGC). You can view the chemical structures in a new window.
In addition to stimulating thermogenesis, green tea has a variety of well documented health benefits. Green tea is an antioxidant that has a strong anticancer effects in skin, stomach, colon, etc. Green tea protects against free radicals and it is a logical addition to any supplement program designed to prevent heart disease. In fact, green tea has so many health benefits that this post will have to focus on its ability to stimulate thermogenesis.
Quick facts: The Dulloo et al. studies (1, 2) used an alcohol extract of green tea that is sold in capsule form under the name EXOLISE (Arkopharma Laboratories, Nice, France). This extract is standardized to 24.7% catechins (70% as EGCG), and 8.35% caffeine.
How Powerful Is Green Tea Thermogenesis?
Scientists have found that green tea stimulates thermogenesis and this effect cannot be completely attributed to its caffeine content because the thermogenic effect of green tea is greater than an equivalent amount of caffeine. An in vitro study by Dulloo et al (2) found that a catechin that is abundant in green tea, EGCG, increased the respiration rate of brown fat (stimulated thermogenesis). Dulloo et al. have also done an in vivo study (1) that involved "10 healthy men" who received (with each meal during a 24 hour test period) on three separate occasions:
Test 1: 50 mg caffeine and 90 mg EGCG (total catechins: 125 mg).
Test 2: 50 mg caffeine.
Test 3: Placebo.
There was a "5-10 day interval between successive 24-h trials for each subject." The conditions were controlled and the study was double blind. However, given the fact that obese people respond differently to sympathetic stimuli, it is unfortunate that these tests were performed on "healthy" subjects. The study accepted people described as ranging from "lean to mildly obese" (8-30% bodyfat). But the responses varied widely nonetheless: 24 hour energy expenditure increased "in 6 of the 10 subjects after treatment with the green tea extract, ranging from 266 to 836 kJ" They did not find a correlation between the magnitude of thermogenic response and the degree of fatness of the subjects. That's not too surprising given the number of subjects and the selection criteria. It's a shame that they didn't include more subjects and some fat people in these tests.
Energy Expenditure
Diurnal and 24 hour energy expenditure was increased significantly during treatment with green tea extract. Nocturnal energy expenditure increased, but not significantly. Here's the numbers:
Diurnal: Green tea 4.5% > placebo; Green tea 3.2% > caffeine.
24 hour: Green tea 3.5 % > placebo; Green tea 2.8 % > caffeine.
Perhaps even more interesting is the fact that the green tea extract produced lower respiratory quotients (helped normalize FAT burning):
"Significant differences across treatments were found during the diurnal, nocturnal, and 24-h periods . . . The contribution of fat oxidation [fat burning] to 24-h EE [energy expenditure] during treatment with the green tea extract (41.5%) was significantly higher (p<0.001) than during placebo [31.6%] treatment" (1).
In addition, urinary nitrogen losses showed no significant differences across treatments during all three periods. Clearly, the increased energy expenditure reflects increased FAT burning. This is worth exploring in greater detail.
Written
Dec 2000
Last Update
Dec 2000
Respiratory Quotient
Now we are getting to the interesting stuff. The lower the respiratory quotient, the more fat you are burning. You will often see this referred to as substrate utilization, substrate oxidation (burning), or fuel mix. It is very encouraging that such a small dose of green tea had such an impressive effect on the RQ: The contribution of fat oxidation [fat burning] to 24-h EE [energy expenditure] during treatment with the green tea extract (41.5%) was significantly higher (p<0.001) than during placebo [31.6%] treatment" [emphasis added] (1). Outside of medical journals, fat oxidation and the respiratory quotient are usually only discussed in relation to aerobic exercise (I'm sure you have been told to do low intensity aerobics to burn more fat). However, as usual, the interesting stuff (the stuff that proves obesity is a REAL disease) is ignored. You see, obese people tend to burn more carbohydrate (glucose) and less fat (fatty acids) than normal people. The Astrup/Toubro team of obesity researchers have studied this defect (4-NA, 5-NA). In fact, a growing number of scientists believe that this part of the thermogenic defect may be more important than energy expenditure. Why do we burn relatively less fat? This is caused be a number of genetic (22) and biochemical defects including insufficient release of noradrenaline and adrenaline. Arne Astrup et al. (5-NA, 22) have written about this genetic defect:
"Direct evidence for a genetic influence on RQ [respiratory quotient] was delivered by Deriaz et al., who studied the relationship between DNA variation at the genes coding for the Na,K-ATPase peptides, RQ, and body fat. Postabsorptive [after a meal] RQ was found to be associated with the alpha2-gene and linked with the beta-gene of the Na,K-ATPase, which suggests that these, or neighboring genes, influence RQ. Twin studies also support the heritability of RQ." [emphasis added] (5-NA).
Based on this study by Dulloo et al. (1), it looks like green tea can help correct this respiratory quotient defect. Of course, ephedrine/caffeine normalizes the release of noradrenaline and adrenaline and corrects the respiratory quotient:
"The respiratory quotient (RQ) indicate that relatively more lipid [fat] was oxidized during chronic ephedrine treatment than in the control study. This change was observed in the fasting state as well as after glucose administration. Certain effects of ephedrine seems to be appropriate to a thermogenic drug for the treatment of obesity: A single dose of ephedrine stimulates thermogenesis, an effect that is enhanced during chronic treatment; Chronic treatment elevates the metabolic rate; and the substrate utilization is changed in favor of lipid [fat] oxidation" [emphasis added] (6).
Is it not curious that doctors tell obese people to eat an abnormally small amount of fat rather than tell us to take thermogenic supplements to correct this genetic fat burning defect? I mean, imagine if your car was having engine trouble and your mechanic refused to fix it and told you to "just drive less." Of course, you would immediately realize that this was a bogus 'solution' and go to another mechanic. But what if they ALL ignored the problem and told you to change your driving habits? Eventually you would realize that you need to read some repair manuals so you can fix the car yourself, right? Fortunately, there is no FDA-type organization trying to pass laws against nonprofessional car repairs.
Obese people who do not want to be mislead by prejudice, ignorance, or political/financial agendas should keep this fuel mix defect in mind when they hear "experts" questioning the importance of thermogenesis. Typically, these "experts" will rattle off a bunch of energy expenditure numbers and tell you that thermogenesis is not very important and thermogenic supplements don't do much. If you want to have some fun, remind the "expert" that there is direct evidence for a genetic influence on respiratory quotient and one of the ways that thermogenic supplements help obese people is by normalizing their defective substrate utilization. Ask the "expert" if he is aware of the fact that a growing number of obesity scientists believe correcting this genetic fat burning defect is more important than those archaic energy expenditure numbers. After all, if you don't BURN fat, you BECOME fat.
Noradrenaline Storage & Release
In order to understand how green tea works we need to take a quick look at noradrenaline storage, release, and metabolism. Noradrenaline is synthesized in the sympathetic nerves and stored in storage vesicles. When sufficiently stimulated, the vesicles migrate to the end of the nerve and release noradrenaline into the synaptic cleft. As you probably already know, the noradrenaline binds to the adrenergic receptors and stimulates thermogenesis. Next in the chain of events is noradrenaline metabolism, which involves two uptake mechanisms.
General references for Noradrenaline Storage, Release, and Metabolism: 3-BK, 20-BK, 21-BK.
Advanced readers should check out "Principles of Neuropsychopharmacology" (3-BK) -- it's an excellent book!
Noradrenaline Metabolism
Uptake 1: After stimulating the adrenergic receptors, 85-90% of the noradrenaline is taken back up into the sympathetic nerves (uptake 1) and stored in vesicles or metabolized by monoamine oxidase (specifically, MAO-A) in the mitochondria. The importance of uptake 1 (neuronal uptake) is reflected by the warnings against combining sympathomimetics (ephedrine, phentermine, etc.) that increase noradrenaline release with MAO inhibitors -- the risk of overstimulation would be much too high.
Uptake 2: Some of the noradrenaline diffuses away from the receptors and is transported by extra-neuronal cells (uptake 2) and metabolized by catechol-O-methyl-transferase (COMT). Green tea increases noradrenaline in the synaptic cleft and safely increases thermogenesis because of its ability to prevent COMT from metabolizing noradrenaline. This is safe because COMT plays a much smaller role in catecholamine dynamics than MAO.
COMT exists in both a soluble and a membrane-bound form. The soluble form of COMT is found in organs and it does not have as high of an affinity for catecholamines as the membrane-bound form.
Quick facts: Uptake 1 of noradrenaline is blocked by cocaine, amphetamines, and tricyclic antidepressants. Progesterone increases MAO and estrogen inhibits MAO.
* There is more information on how caffeine enhances thermogenesis in the following posts: How ECA Works has illustrations and there is referenced information in The "A" in ECA and my Thermogenic FAQ.
How Green Tea Stimulates Thermogenesis
The thermogenic effect of green tea involves two mechanisms: I.) green tea contains a catechin, EGCG, which inhibits catechol O-methyltransferase (COMT), an enzyme that degrades noradrenaline II.) the caffeine in green tea increases intracellular cAMP accumulation by inhibiting the enzyme, phosphodiesterase. See "How ECA Works" for more info on the importance of caffeine.
I have already discussed the effects of caffeine in several posts, so I will focus on COMT. Interestingly, the medical literature showing that green tea inhibits COMT dates back over two decades (7-NA). By inhibiting COMT, green tea prolongs the life of noradrenaline in the synaptic cleft. (This lets noradrenaline stimulate the receptors for a longer time before it is metabolized). The in vivo (human) study by Dulloo et al. (1) found that, compared to placebo and caffeine, green tea significantly increased total 24 hour urinary noradrenaline excretion. The researchers commented on the significance of this:
"This observation is consistent with the inhibiting effect of green tea on COMT, the consequential reduction in norepinephrine [noradrenaline] degradation, and hence, the spillover of norepinephrine into circulation, thereby accounting for the higher urinary excretion of norepinephrine. Such effects, resulting in a prolonged life of norepinephrine in the sympathetic synaptic cleft, could explain the observed effects of the extract in stimulating thermogenesis and fat oxidation" (1).
Written
Dec 2000
Last Update
Dec 2000
Discussion
Although this research is exciting, the fact remains that green tea does NOT normalize the release of noradrenaline (the primary obesity-causing defect) -- it prolongs the action of whatever amount of noradrenaline that your body is able to release. For this reason, Dulloo concluded that the thermogenic effect of green tea is "likely to be highly dependent upon the release of endogenous NA [noradrenaline]." Clearly, green tea (by itself) is going to be a "your mileage may vary" situation. However, tissue studies performed by Dulloo et al. showed that green tea produced a significant synergistic effect when it was combined with ephedrine or ephedrine/caffeine (2).
Since green tea prolongs the action of noradrenaline, you would think that it would have a stimulatory effect. However, Dulloo et al. noted that green tea caused no significant differences in heart rate. The most logical explanation for this is that the stimulatory effect of increased noradrenaline action is being countered by other mechanisms. For example, green tea contains the amino acid, theanine, which has been found to lower blood pressure (. Green tea also has a vasorelaxing effect (9, 10). One recent study found that regular tea consumption had no significant effect on blood pressure (11), but it is difficult to achieve a therapeutic dose without taking concentrated supplements. Further complicating the picture, however, is the fact that they also found that green and black tea caused a short term increase in blood pressure (11).
I hope there will be further research aimed at determining the optimal dosage for the ephedrine/caffeine/green tea combination. It seems likely that the addition of green tea will make it possible to normalize sympathetic tone with a less stimulating stack. In addition, green tea (without ephedrine/caffeine) may permit people with hypertension to obtain a mild increase in fat oxidation and thermogenesis. Clearly, additional research is needed to expand our understanding of the effect of green tea on blood pressure. Hypertensives that want to take green tea should definitely work with a doctor and monitor their blood pressure.
Green tea is an extremely logical supplement for obese people. In addition to its weight loss effect, green tea protects against a number of conditions that are VERY common among the obese:
Green tea has been found to reduce the risk of having a stroke (12, 13).
Green tea has anti-cancer and anti-tumor effects (14, 15).
Green tea can improve glucose/insulin levels and your blood lipid profile (16, 17, 18-NA, 19).
However, it is difficult to obtain all of these health benefits if one does not take green tea supplements -- without supplements, you would have to drink at least ten cups of green tea every day!
Green Tea Products
Green tea has so many health benefits that it's impossible to pick a single best product. The only logical way to evaluate green tea products is to separate them according to their suitability for specific purposes such as weight loss, blood pressure reduction, etc. If you are interested in green tea for cancer prevention and health enhancement, I would shoot for at least 10 cups of tea per day. That's a lot of tea! Perhaps a combination of supplements and drinking tea is the easiest way to consume enough tea.
For the price comparison, whenever possible, I calculated the price per 100 mg of polyphenols and the price per 100 mg of EGCG. These calculations make it easy to compare products with different size capsules and extracts that are standardized to different potencies. I was surprised to find that, based on polyphenol and EGCG content, there were huge price differences between products. For example, Natrol Green Tea Extract is only 3.6 cents per 100 mg of polyphenols; Natures Way Green Tea Extract is a whopping 28.21 cents.
Green Tea For Weight Loss
Research suggests that EGCG is the most important catechin for weight loss. Although most products specify the amount of polyphenols, only a few list the EGCG content. For weight loss purposes, the most powerful Green Tea extract is the standardized Green Tea Extract by NSI -- it contains a whopping 220 mg of EGCG per capsule. The second most powerful green tea extract is the Life Extension Super Green Tea Extract, which contains 122 mg of EGCG per capsule.
Apparently, all of these green tea extracts that are standardized to extremely high levels of EGCG contain very little caffeine. This is good if you are adding green tea to win ECA stack; however, if you are interested in using one of these high EGCG green tea supplements by itself, you'll get much better results if you take some caffeine with it.
Dulloo AG, Duret C, Rohrer D, Girardier L, Mensi N, Fathi M, Chantre P, Vandermander J "Efficacy of a green tea extract rich in catechin polyphenols and caffeine in increasing 24-h energy expenditure and fat oxidation in humans" Am J Clin Nutr 1999, Vol 70 (6), Pg 1040-5. PMID: 0010584049.
2.) Dulloo AG, Seydoux J, Girardier L, Chantre P, Vandermander J "Green tea and thermogenesis: interactions between catechin-polyphenols, caffeine and sympathetic activity" Int J Obes Relat Metab Disord 2000, Vol 24 (2), Pg 252-8. PMID: 0010702779.
3-BK.) Feldman, RS; Meyer, JS, and Quenzer, LF "Principles of Neuropsychopharmacology" Sinauer Associates, Inc. 1997.
4-NA.) Astrup A, Buemann B, Toubro S, Raben A "Defects in substrate oxidation involved in the predisposition to obesity" Proc Nutr Soc 1996, Vol 55 (3), Pg 817-28. PMID: 0009004326.
5-NA.) Astrup A, Raben A, Buemann B, Toubro S "Fat metabolism in the predisposition to obesity" Ann N Y Acad Sci 1997, Vol 827 Pg 417-30. PMID: 0009329772.
6.) Astrup A, Madsen J, Holst JJ, Christensen NJ "The effect of chronic ephedrine treatment on substrate utilization, the sympathoadrenal activity, and energy expenditure during glucose-induced thermogenesis in man" Metabolism 1986, Vol 35 (3), Pg 260-5. PMID: 0003512957.
7-NA.) Borchardt RT and Huber JA "Catechol O-methyltransferase. 5. Structure-activity relationships for inhibition by flavonoids" J Med Chem 1975, Vol 18 (1), Pg 120-2. PMID: 0001109569.
8.) Yokogoshi H, Kato Y, Sagesaka YM, Takihara-Matsuura T, Kakuda T, Takeuchi N "Reduction effect of theanine on blood pressure and brain 5- hydroxyindoles in spontaneously hypertensive rats" Biosci Biotechnol Biochem 1995, Vol 59 (4), Pg 615-8. PMID: 0007539642.
9.) Huang Y, Zhang A, Lau CW, Chen ZY "Vasorelaxant effects of purified green tea epicatechin derivatives in rat mesenteric artery" Life Sci 1998, Vol 63 (4), Pg 275-83. PMID: 0009698036.
10.) Huang Y, Chan NW, Lau CW, Yao XQ, Chan FL, Chen ZY "Involvement of endothelium/nitric oxide in vasorelaxation induced by purified green tea (-)epicatechin" Biochim Biophys Acta 1999, Vol 1427 (2), Pg 322-8. PMID: 0010216249.
11.) Hodgson JM, Puddey IB, Burke V, Beilin LJ, Jordan N "Effects on blood pressure of drinking green and black tea" J Hypertens 1999, Vol 17 (4), Pg 457-63. PMID: 0010404946.
12.) Sato Y, Nakatsuka H, Watanabe T, Hisamichi S, Shimizu H, Fujisaku S, Ichinowatari Y, Ida Y, Suda S, Kato K and others. "Possible contribution of green tea drinking habits to the prevention of stroke" Tohoku J Exp Med 1989, Vol 157 (4), Pg 337-43. PMID: 0002741170.
13.) Uchida S, Ozaki M, Akashi T, Yamashita K, Niwa M, Taniyama K "Effects of (-)-epigallocatechin-3-O-gallate (green tea tannin) on the life span of stroke-prone spontaneously hypertensive rats" Clin Exp Pharmacol Physiol Suppl 1995, Vol 1 Pg S302-3. PMID: 0009072402.
14.) Kono S, Ikeda M, Tokudome S, Kuratsune M "A case-control study of gastric cancer and diet in northern Kyushu, Japan" Jpn J Cancer Res 1988, Vol 79 (10), Pg 1067-74. PMID: 0003143695.
15.) Ruch RJ, Cheng SJ, Klaunig JE "Prevention of cytotoxicity and inhibition of intercellular communication by antioxidant catechins isolated from Chinese green tea" Carcinogenesis 1989, Vol 10 (6), Pg 1003-8. PMID: 0002470525.
16.) Karawya MS, Abdel Wahab SM, El-Olemy MM, Farrag NM "Diphenylamine, an antihyperglycemic agent from onion and tea" J Nat Prod 1984, Vol 47 (5), Pg 775-80. PMID: 0006512531.
17.) Muramatsu K, Fukuyo M, Hara Y "Effect of green tea catechins on plasma cholesterol level in cholesterol-fed rats" J Nutr Sci Vitaminol (Tokyo) 1986, Vol 32 (6), Pg 613-22. PMID: 0003585557.
18-NA.) Chisaka T, Matsuda H, Kubomura Y, Mochizuki M, Yamahara J, Fujimura H "The effect of crude drugs on experimental hypercholesteremia: mode of action of (-)-epigallocatechin gallate in tea leaves" Chem Pharm Bull (Tokyo) 1988, Vol 36 (1), Pg 227-33. PMID: 0003378286.
19.) Yokozawa T and Dong E "Influence of green tea and its three major components upon low-density lipoprotein oxidation" Exp Toxicol Pathol 1997, Vol 49 (5), Pg 329-35. PMID: 0009455677.
20-BK.) Greenspan, FS and Gardner, DG "Basic & Clinical Endocrinology" Lange Medical Books/McGraw-Hill 2000.
21-BK.) Munson, PL; Mueller, RA, and Breese, GR "Principles of Pharmacology. Basic Concepts & Clinical Applications." Chapman & Hall 1996.
22.) Deriaz O, Dionne F, Perusse L, Tremblay A, Vohl MC, Cote G, Bouchard C "DNA variation in the genes of the Na,K-adenosine triphosphatase and its relation with resting metabolic rate, respiratory quotient, and body fat" J Clin Invest 1994, Vol 93 (2), Pg 838-43. PMID: 0007509349.
bicepts101
New member
awsome info....thats what u do best....its better to stay out of those catsfights
karma
karma
slat1
New member
Here is some more info:
What is Green Tea Extract?
When we first learned of the incredible new discoveries concerning green tea, we thought we were in for a long and tedious education on teas (we're all devoted coffee drinkers!). But we were pleasantly surprised (and our science writer quit coffee in favor of green tea!). Don't be daunted by the apparent myriad varieties of tea; by "tea" we mean the leaf of the plant, Camellia sinensis - other so-called "herbal teas" (a misnomer because Camellia sinensis is an herb) are meant to be any infusion other than that of Camellia sinensis. There are really only three categories of teas: green, oolong, and black. Each of these is the leaf of Camellia sinensis and differs only in duration of fermentation: "black" is fully fermented, "oolong" is partially fermented, and "green" is not fermented at all, only steamed. Types of tea such as Ceylon and Darjeeling refer to the region in which they are grown.
For What, and How is Green Tea Extract Used?
What is amazing about green tea is its reported ability to ward off many types of cancer. Much of the initial evidence that green tea is anti-carcinogenic is based on epidemiological studies which show lower rates of many types of cancer among populations such as Japan and China that drink green tea as part of a daily cultural habit. Recently, however, controlled studies on green tea extract have yielded impressive results, identifying the polyphenol (-)-epigallocatechin gallate (EGCG) as the responsible component. EGCG is able to force certain cancer cells into a situation in which, incredible as it may seem, they must die or be killed; the cancer cells die in a sort of cellular suicide, a condition scientists call "apoptosis". Further evidence shows EGCG as having an inhibitory effect on the enzyme, urokinase, which is required for tumor formation, thus preventing the formation of tumors in the first place.3,4,8-11,14-20,22-27,35
Not only are the polyphenols in green tea protective against certain cancers, but they are also potent antioxidants. Green tea's antioxidants have been shown to be highly beneficial to the heart - they help prevent the oxidation of LDL cholesterol.29-33
Things to know about Green Tea:
Epidemiological studies have examined green tea drinkers; controlled studies have largely been done on the extract of green tea. Both are beneficial.
One cup of green tea contains from 100-200mg of EGCG.
Green tea should not be steeped in boiling water, but hot water (around 160-200 degrees). Use 1 Teaspoon of loose tea per cup, and a little more than 1 cup of water.
Decaffeinated green tea does not show the same benefits as green tea left in its natural state.
Adding milk negates green tea's beneficial properties.
Black tea may increase the incidence of certain cancers. Don't drink it.
More than 5 cups a day may increase your odds for pancreatic cancer; 1-4 cups shows only benefits, so 1 or 2 cups a day is probably just right.
Green Tea References / Additional Resources
Annabi, B., M. P. Lachambre, N. Bousquet-Gagnon, M. Page, D. Gingras and R. Beliveau (2002). "Green tea polyphenol (-)-epigallocatechin 3-gallate inhibits MMP-2 secretion and MT1-MMP-driven migration in glioblastoma cells." Biochim Biophys Acta 1542(1-3): 209-20.
Aucamp, J., A. Gaspar, Y. Hara and Z. Apostolides (1997). "Inhibition of xanthine oxidase by catechins from tea (Camellia sinensis)." Anticancer Res 17(6D): 4381-5.
Brown, M. D. (1999). "Green tea (Camellia sinensis) extract and its possible role in the prevention of cancer." Altern Med Rev 4(5): 360-70.
Higashi-Okai, K. and Y. Okai (1998). "Potent suppressive activity of chlorophyll a and b from green tea (Camellia sinensis) against tumor promotion in mouse skin." J Uoeh 20(3): 181-8.
Jodoin, J., M. Demeule and R. Beliveau (2002). "Inhibition of the multidrug resistance P-glycoprotein activity by green tea polyphenols." Biochim Biophys Acta 1542(1-3): 149-59.
Kapadia, G. J., B. D. Paul, E. B. Chung, B. Ghosh and S. N. Pradhan (1976). "Carcinogenicity of Camellia sinensis (tea) and some tannin-containing folk medicinal herbs administered subcutaneously in rats." J Natl Cancer Inst 57(1): 207-9.
Katiyar, S. K., R. Agarwal, Z. Y. Wang, A. K. Bhatia and H. Mukhtar (1992). "(-)-Epigallocatechin-3-gallate in Camellia sinensis leaves from Himalayan region of Sikkim: inhibitory effects against biochemical events and tumor initiation in Sencar mouse skin." Nutr Cancer 18(1): 73-83.
Katiyar, S. K. and H. Mukhtar (1997). "Tea antioxidants in cancer chemoprevention." J Cell Biochem Suppl 27: 59-67.
Kavanagh, K. T., L. J. Hafer, D. W. Kim, K. K. Mann, D. H. Sherr, A. E. Rogers and G. E. Sonenshein (2001). "Green tea extracts decrease carcinogen-induced mammary tumor burden in rats and rate of breast cancer cell proliferation in culture." J Cell Biochem 82(3): 387-98.
Mukhtar, H., Z. Y. Wang, S. K. Katiyar and R. Agarwal (1992). "Tea components: antimutagenic and anticarcinogenic effects." Prev Med 21(3): 351-60.
Okai, Y. and K. Higashi-Okai (1997). "Potent suppressive activity of nonpolyphenolic fraction of green tea (Camellia sinensis) against genotoxin-induced umu C gene expression in Salmonella typhimurium (TA 1535/pSK 1002), tumor promotor-dependent ornithine decarboxylase induction of BALB/c 3T3 fibroblast cells, and chemically induced mouse skin tumorigenesis." Teratog Carcinog Mutagen 17(6): 305-12.
Sakamoto, K. (2000). "Synergistic effects of thearubigin and genistein on human prostate tumor cell (PC-3) growth via cell cycle arrest." Cancer Lett 151(1): 103-9.
Weisburger, J. H. (1997). "Tea and health: a historical perspective." Cancer Lett 114(1-2): 315-7.
Shim, J. S., M. H. Kang, Y. H. Kim, J. K. Roh, C. Roberts and I. P. Lee (1995). "Chemopreventive effect of green tea (Camellia sinensis) among cigarette smokers." Cancer Epidemiol Biomarkers Prev 4(4): 387-91.
Valcic, S., B. N. Timmermann, D. S. Alberts, G. A. Wachter, M. Krutzsch, J. Wymer and J. M. Guillen (1996). "Inhibitory effect of six green tea catechins and caffeine on the growth of four selected human tumor cell lines." Anticancer Drugs 7(4): 461-8.
Yang, C. S., J. Y. Chung, G. Yang, S. K. Chhabra and M. J. Lee (2000). "Tea and tea polyphenols in cancer prevention." J Nutr 130(2S Suppl): 472S-478S.
Yang, C. S., S. Prabhu and J. Landau (2001). "Prevention of carcinogenesis by tea polyphenols." Drug Metab Rev 33(3-4): 237-53.
Hastak, K., S. Gupta, et al. (2003). "Role of p53 and NF-kappaB in epigallocatechin-3-gallate-induced apoptosis of LNCaP cells." Oncogene 22(31): 4851-9.
Rosengren, R. J. (2003). "Catechins and the treatment of breast cancer: Possible utility and mechanistic targets." IDrugs 6(11): 1073-8.
Pilorget, A., V. Berthet, et al. (2003). "Medulloblastoma cell invasion is inhibited by green tea (-)epigallocatechin-3-gallate." J Cell Biochem 90(4): 745-55.
Lambert, J. D. and C. S. Yang (2003). "Mechanisms of cancer prevention by tea constituents." J Nutr 133(10): 3262S-3267S.
Kemberling, J. K., J. A. Hampton, et al. (2003). "Inhibition of bladder tumor growth by the green tea derivative epigallocatechin-3-gallate." J Urol 170(3): 773-6.
Einspahr, J. G., G. T. Bowden, et al. (2003). "Skin cancer chemoprevention: strategies to save our skin." Recent Results Cancer Res 163: 151-64; discussion 264-6.
Adhami, V. M., N. Ahmad, et al. (2003). "Molecular targets for green tea in prostate cancer prevention." J Nutr 133(7 Suppl): 2417S-2424S.
Ahn, W. S., S. W. Huh, et al. (2003). "A major constituent of green tea, EGCG, inhibits the growth of a human cervical cancer cell line, CaSki cells, through apoptosis, G(1) arrest, and regulation of gene expression." DNA Cell Biol 22(3): 217-24.
Morre, D. J., D. M. Morre, et al. (2003). "Tea catechin synergies in inhibition of cancer cell proliferation and of a cancer specific cell surface oxidase (ECTO-NOX)." Pharmacol Toxicol 92(5): 234-41.
Fujiki, H., M. Suganuma, et al. (2003). "New TNF-alpha releasing inhibitors as cancer preventive agents from traditional herbal medicine and combination cancer prevention study with EGCG and sulindac or tamoxifen." Mutat Res 523-524: 119-25.
Katiyar, S. K. (2003). "Skin photoprotection by green tea: antioxidant and immunomodulatory effects." Curr Drug Targets Immune Endocr Metabol Disord 3(3): 234-42.
Raederstorff, D. G., M. F. Schlachter, et al. (2003). "Effect of EGCG on lipid absorption and plasma lipid levels in rats." J Nutr Biochem 14(6): 326-32.
Miura, Y., T. Chiba, et al. (2001). "Tea catechins prevent the development of atherosclerosis in apoprotein E-deficient mice." J Nutr 131(1): 27-32.
Osada, K., M. Takahashi, et al. (2001). "Tea catechins inhibit cholesterol oxidation accompanying oxidation of low density lipoprotein in vitro." Comp Biochem Physiol C Toxicol Pharmacol 128(2): 153-64.
Miura, S., J. Watanabe, et al. (1995). "Effects of various natural antioxidants on the Cu(2+)-mediated oxidative modification of low density lipoprotein." Biol Pharm Bull 18(1): 1-4.
Miura, S., J. Watanabe, et al. (1994). "The inhibitory effects of tea polyphenols (flavan-3-ol derivatives) on Cu2+ mediated oxidative modification of low density lipoprotein." Biol Pharm Bull 17(12): 1567-72.
Double-Blind Placebo-Controlled Trials
Dulloo, A. G., C. Duret, D. Rohrer, L. Girardier, N. Mensi, M. Fathi, P. Chantre and J. Vandermander (1999). "Efficacy of a green tea extract rich in catechin polyphenols and caffeine in increasing 24-h energy expenditure and fat oxidation in humans." Am J Clin Nutr 70(6): 1040-5.
Placebo-Controlled Trials
Stratton, S. P., R. T. Dorr, et al. (2000). "The state-of-the-art in chemoprevention of skin cancer." Eur J Cancer 36(10): 1292-7.
I love the stuff. One to two cups in the morning. I don't drink the java so this is a good replacement. Seems to help me lose fat too.
What is Green Tea Extract?
When we first learned of the incredible new discoveries concerning green tea, we thought we were in for a long and tedious education on teas (we're all devoted coffee drinkers!). But we were pleasantly surprised (and our science writer quit coffee in favor of green tea!). Don't be daunted by the apparent myriad varieties of tea; by "tea" we mean the leaf of the plant, Camellia sinensis - other so-called "herbal teas" (a misnomer because Camellia sinensis is an herb) are meant to be any infusion other than that of Camellia sinensis. There are really only three categories of teas: green, oolong, and black. Each of these is the leaf of Camellia sinensis and differs only in duration of fermentation: "black" is fully fermented, "oolong" is partially fermented, and "green" is not fermented at all, only steamed. Types of tea such as Ceylon and Darjeeling refer to the region in which they are grown.
For What, and How is Green Tea Extract Used?
What is amazing about green tea is its reported ability to ward off many types of cancer. Much of the initial evidence that green tea is anti-carcinogenic is based on epidemiological studies which show lower rates of many types of cancer among populations such as Japan and China that drink green tea as part of a daily cultural habit. Recently, however, controlled studies on green tea extract have yielded impressive results, identifying the polyphenol (-)-epigallocatechin gallate (EGCG) as the responsible component. EGCG is able to force certain cancer cells into a situation in which, incredible as it may seem, they must die or be killed; the cancer cells die in a sort of cellular suicide, a condition scientists call "apoptosis". Further evidence shows EGCG as having an inhibitory effect on the enzyme, urokinase, which is required for tumor formation, thus preventing the formation of tumors in the first place.3,4,8-11,14-20,22-27,35
Not only are the polyphenols in green tea protective against certain cancers, but they are also potent antioxidants. Green tea's antioxidants have been shown to be highly beneficial to the heart - they help prevent the oxidation of LDL cholesterol.29-33
Things to know about Green Tea:
Epidemiological studies have examined green tea drinkers; controlled studies have largely been done on the extract of green tea. Both are beneficial.
One cup of green tea contains from 100-200mg of EGCG.
Green tea should not be steeped in boiling water, but hot water (around 160-200 degrees). Use 1 Teaspoon of loose tea per cup, and a little more than 1 cup of water.
Decaffeinated green tea does not show the same benefits as green tea left in its natural state.
Adding milk negates green tea's beneficial properties.
Black tea may increase the incidence of certain cancers. Don't drink it.
More than 5 cups a day may increase your odds for pancreatic cancer; 1-4 cups shows only benefits, so 1 or 2 cups a day is probably just right.
Green Tea References / Additional Resources
Annabi, B., M. P. Lachambre, N. Bousquet-Gagnon, M. Page, D. Gingras and R. Beliveau (2002). "Green tea polyphenol (-)-epigallocatechin 3-gallate inhibits MMP-2 secretion and MT1-MMP-driven migration in glioblastoma cells." Biochim Biophys Acta 1542(1-3): 209-20.
Aucamp, J., A. Gaspar, Y. Hara and Z. Apostolides (1997). "Inhibition of xanthine oxidase by catechins from tea (Camellia sinensis)." Anticancer Res 17(6D): 4381-5.
Brown, M. D. (1999). "Green tea (Camellia sinensis) extract and its possible role in the prevention of cancer." Altern Med Rev 4(5): 360-70.
Higashi-Okai, K. and Y. Okai (1998). "Potent suppressive activity of chlorophyll a and b from green tea (Camellia sinensis) against tumor promotion in mouse skin." J Uoeh 20(3): 181-8.
Jodoin, J., M. Demeule and R. Beliveau (2002). "Inhibition of the multidrug resistance P-glycoprotein activity by green tea polyphenols." Biochim Biophys Acta 1542(1-3): 149-59.
Kapadia, G. J., B. D. Paul, E. B. Chung, B. Ghosh and S. N. Pradhan (1976). "Carcinogenicity of Camellia sinensis (tea) and some tannin-containing folk medicinal herbs administered subcutaneously in rats." J Natl Cancer Inst 57(1): 207-9.
Katiyar, S. K., R. Agarwal, Z. Y. Wang, A. K. Bhatia and H. Mukhtar (1992). "(-)-Epigallocatechin-3-gallate in Camellia sinensis leaves from Himalayan region of Sikkim: inhibitory effects against biochemical events and tumor initiation in Sencar mouse skin." Nutr Cancer 18(1): 73-83.
Katiyar, S. K. and H. Mukhtar (1997). "Tea antioxidants in cancer chemoprevention." J Cell Biochem Suppl 27: 59-67.
Kavanagh, K. T., L. J. Hafer, D. W. Kim, K. K. Mann, D. H. Sherr, A. E. Rogers and G. E. Sonenshein (2001). "Green tea extracts decrease carcinogen-induced mammary tumor burden in rats and rate of breast cancer cell proliferation in culture." J Cell Biochem 82(3): 387-98.
Mukhtar, H., Z. Y. Wang, S. K. Katiyar and R. Agarwal (1992). "Tea components: antimutagenic and anticarcinogenic effects." Prev Med 21(3): 351-60.
Okai, Y. and K. Higashi-Okai (1997). "Potent suppressive activity of nonpolyphenolic fraction of green tea (Camellia sinensis) against genotoxin-induced umu C gene expression in Salmonella typhimurium (TA 1535/pSK 1002), tumor promotor-dependent ornithine decarboxylase induction of BALB/c 3T3 fibroblast cells, and chemically induced mouse skin tumorigenesis." Teratog Carcinog Mutagen 17(6): 305-12.
Sakamoto, K. (2000). "Synergistic effects of thearubigin and genistein on human prostate tumor cell (PC-3) growth via cell cycle arrest." Cancer Lett 151(1): 103-9.
Weisburger, J. H. (1997). "Tea and health: a historical perspective." Cancer Lett 114(1-2): 315-7.
Shim, J. S., M. H. Kang, Y. H. Kim, J. K. Roh, C. Roberts and I. P. Lee (1995). "Chemopreventive effect of green tea (Camellia sinensis) among cigarette smokers." Cancer Epidemiol Biomarkers Prev 4(4): 387-91.
Valcic, S., B. N. Timmermann, D. S. Alberts, G. A. Wachter, M. Krutzsch, J. Wymer and J. M. Guillen (1996). "Inhibitory effect of six green tea catechins and caffeine on the growth of four selected human tumor cell lines." Anticancer Drugs 7(4): 461-8.
Yang, C. S., J. Y. Chung, G. Yang, S. K. Chhabra and M. J. Lee (2000). "Tea and tea polyphenols in cancer prevention." J Nutr 130(2S Suppl): 472S-478S.
Yang, C. S., S. Prabhu and J. Landau (2001). "Prevention of carcinogenesis by tea polyphenols." Drug Metab Rev 33(3-4): 237-53.
Hastak, K., S. Gupta, et al. (2003). "Role of p53 and NF-kappaB in epigallocatechin-3-gallate-induced apoptosis of LNCaP cells." Oncogene 22(31): 4851-9.
Rosengren, R. J. (2003). "Catechins and the treatment of breast cancer: Possible utility and mechanistic targets." IDrugs 6(11): 1073-8.
Pilorget, A., V. Berthet, et al. (2003). "Medulloblastoma cell invasion is inhibited by green tea (-)epigallocatechin-3-gallate." J Cell Biochem 90(4): 745-55.
Lambert, J. D. and C. S. Yang (2003). "Mechanisms of cancer prevention by tea constituents." J Nutr 133(10): 3262S-3267S.
Kemberling, J. K., J. A. Hampton, et al. (2003). "Inhibition of bladder tumor growth by the green tea derivative epigallocatechin-3-gallate." J Urol 170(3): 773-6.
Einspahr, J. G., G. T. Bowden, et al. (2003). "Skin cancer chemoprevention: strategies to save our skin." Recent Results Cancer Res 163: 151-64; discussion 264-6.
Adhami, V. M., N. Ahmad, et al. (2003). "Molecular targets for green tea in prostate cancer prevention." J Nutr 133(7 Suppl): 2417S-2424S.
Ahn, W. S., S. W. Huh, et al. (2003). "A major constituent of green tea, EGCG, inhibits the growth of a human cervical cancer cell line, CaSki cells, through apoptosis, G(1) arrest, and regulation of gene expression." DNA Cell Biol 22(3): 217-24.
Morre, D. J., D. M. Morre, et al. (2003). "Tea catechin synergies in inhibition of cancer cell proliferation and of a cancer specific cell surface oxidase (ECTO-NOX)." Pharmacol Toxicol 92(5): 234-41.
Fujiki, H., M. Suganuma, et al. (2003). "New TNF-alpha releasing inhibitors as cancer preventive agents from traditional herbal medicine and combination cancer prevention study with EGCG and sulindac or tamoxifen." Mutat Res 523-524: 119-25.
Katiyar, S. K. (2003). "Skin photoprotection by green tea: antioxidant and immunomodulatory effects." Curr Drug Targets Immune Endocr Metabol Disord 3(3): 234-42.
Raederstorff, D. G., M. F. Schlachter, et al. (2003). "Effect of EGCG on lipid absorption and plasma lipid levels in rats." J Nutr Biochem 14(6): 326-32.
Miura, Y., T. Chiba, et al. (2001). "Tea catechins prevent the development of atherosclerosis in apoprotein E-deficient mice." J Nutr 131(1): 27-32.
Osada, K., M. Takahashi, et al. (2001). "Tea catechins inhibit cholesterol oxidation accompanying oxidation of low density lipoprotein in vitro." Comp Biochem Physiol C Toxicol Pharmacol 128(2): 153-64.
Miura, S., J. Watanabe, et al. (1995). "Effects of various natural antioxidants on the Cu(2+)-mediated oxidative modification of low density lipoprotein." Biol Pharm Bull 18(1): 1-4.
Miura, S., J. Watanabe, et al. (1994). "The inhibitory effects of tea polyphenols (flavan-3-ol derivatives) on Cu2+ mediated oxidative modification of low density lipoprotein." Biol Pharm Bull 17(12): 1567-72.
Double-Blind Placebo-Controlled Trials
Dulloo, A. G., C. Duret, D. Rohrer, L. Girardier, N. Mensi, M. Fathi, P. Chantre and J. Vandermander (1999). "Efficacy of a green tea extract rich in catechin polyphenols and caffeine in increasing 24-h energy expenditure and fat oxidation in humans." Am J Clin Nutr 70(6): 1040-5.
Placebo-Controlled Trials
Stratton, S. P., R. T. Dorr, et al. (2000). "The state-of-the-art in chemoprevention of skin cancer." Eur J Cancer 36(10): 1292-7.
I love the stuff. One to two cups in the morning. I don't drink the java so this is a good replacement. Seems to help me lose fat too.
MassiveG300
New member
A lot of people report superior anti-inflammatory results with green tea use.slat1 said:
MassiveG300 said:A lot of people report superior anti-inflammatory results with green tea use.
That's most likely due to the Catechin content of the Green tea.
The Polyphenol content protects against virus's, mutations etc...
The ECGCG componenent is the thermogenic component.
So, if it's joint pain reduction you're after try to get a GT that's standardized for the highest possible % of catechins.
bicepts101
New member
awsome supp
1 year ago..if someone asked me to try green tea, i would have been like wtf is that?...lol
1 year ago..if someone asked me to try green tea, i would have been like wtf is that?...lol
Fonz said:
First off ... very good info Fonz! Unreal. K to you my bro!
So has anyone actually tried the NSI stuff?
http://www.vitacost.com/Store/Products/ProductDescription.cfm?SKUNumber=0145
Looking for some feedback.
Cheers,
Mavy
Bumparoni - anyone try the NSI Stuff??
The more I read about green tea, it seems to be like a miracle drug with all of its benefits. Sounds like something I may add to my arsenal of dailly vitamins. Thats the reason why those chinese guys live to be 120 years old.
Mavy
BUMP!
The more I read about green tea, it seems to be like a miracle drug with all of its benefits. Sounds like something I may add to my arsenal of dailly vitamins. Thats the reason why those chinese guys live to be 120 years old.
Mavy
BUMP!
bicepts101
New member
Mavy said:
exaclty bro
read up on some of their liver cleansing methods
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